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Multiple interferon regulatory factor and NF-κB sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells

CD83 is one of the best-known surface markers for fully mature dendritic cells (mature DCs), and its cell-type- and maturation-specific regulation makes the CD83 promoter an interesting tool for the genetic modulation of DCs. To determine the mechanisms regulating this DC- and maturation-specific CD83 expression, chromatin immunoprecipitation (ChIP)-on-chip microarray, biocomputational, reporter,

Late age at first full-term pregnancy as a risk factor for women with malignant lymphoma

Women with malignant lymphoma, non-Hodgkin's lymphoma and Hodgkin's disease were of a significantly later age at first full-term pregnancy (AFFP) than controls without malignant disorders. The odds ratio (OR) of having the first pregnancy at 30 years of fertility was 6.4 for women with malignant lymphoma. This ratio was higher than the ratio of 3.9 in a group of breast cancer patients. A low parit

Software-based data acquisition and processing for neutron detectors at European Spallation Source - Early experience from four detector designs

European Spallation Source (ESS) will deliver neutrons at high flux for use in diverse neutron scattering techniques. The neutron source facility and the scientific instruments will be located in Lund, and the Data Management and Software Centre (DMSC), in Copenhagen. A number of detector prototypes are being developed at ESS together with its European in-kind partners, for example: SoNDe, Multi-G

Heat production rate in blood lymphocytes as a prognostic factor in non‐Hodgkin's lymphoma

Abstract: The heat production rate in peripheral blood lymphocytes was evaluated by direct calorimetry in 76 untreated adults with non‐Hodgkin's lymphoma (NHL). Elevated values were recorded for 20 out of 54 patients with lymphomas of high or intermediate malignancy grade (37%) and for 1 out of 22 patients (5%) with low grade lymphomas (p = 0.01). Median survival was 39 months for patients with no

Country of ownership change in the premium segment : consequences for brand image

Purpose: This paper aims to explore how the ownership transfer from a highly industrialised country to less industrialised countries influences consumers’ brand perceptions. Design/methodology/approach: Three acquisition cases of premium car brands (Jaguar, Land Rover and Volvo) are investigated using qualitative data from online brand communities. Findings: When country of ownership (COOW) for br

Rising incidence of breast cancer among young women in Sweden

The national Swedish cancer registry was used to analyse the age-specific time trends in breast cancer incidence in Sweden from 1970 to 1984. The analysis included both a calendar year and a birth cohort approach to estimate time trends in disease occurrence. According to the birth cohort approach there was a statistically significant increase in the incidence with an average annual increase of th

Deletion of 14q in non‐Hodgkin's lymphoma

Abstract: 6 patients with non‐Hodgkin's lymphoma [3 with small cell lymphocytic lymphoma of B‐cell type (SL), and 1 each with follicular centroblastic/centrocytic, centroblastic, and immunoblastic lymphoma] and with the acquired cytogenetic abnormalities del(14) (q22) or del(14) (q24) are described. An evaluation of these 6 cases and 41 other lymphatic neoplasms with 14q deletion known from the li

A survey on the factors affecting horizontal assisted evacuation in hospitals

This paper presents the results of a survey on assisted evacuation conducted with 120 hospital staff members in Sweden. Staff members included people with different roles in the hospital (e.g. doctors, nurses, department heads, etc.). The survey consisted of a questionnaire aiming at investigating the factors which affect assisted evacuation in hospitals and the current status of assisted evacuati

Comparison of sprinkler activation times under flat and corrugated metal deck ceiling

The distance of sprinklers below ceiling is of fundamental importance since it has a great influence on activation time. Accepted distances are specified in different sprinkler standards such as NFPA 13, FM 2-0 and EN 12845 for different configurations. This distance is unambiguously defined for flat smooth ceilings, but for corrugated ceilings, such as corrugated metal deck ceilings found in many

Estrogen and progesterone receptor analyses in more than 4000 human breast cancer samples : A study with special reference to age at diagnosis and stability of analyses

Estrogen (ER) and progesterone receptors (PgR) were measured in the same laboratory in more than 4000 breast cancer biopsy samples obtained from 15 different hospitals during ten years. ER was measured with isoelectric focusing and PgR with the dextran-coated charcoal method and Scatchard analysis. The distribution pattern for both ER and PgR was during this time period and for the different hospi

Heat release and flame spread assessment of insulation in External Thermal Insulation Composite System (ETICS) facades

External Thermal Insulation Composite Systems (ETICS) represent a popular modern facade for reducing energy consumption, particularly in retrofit applications. Insulation - typically in the form of either EPS (expanded polystyrene) or mineral wool - is applied to the exterior of buildings using mortar adhesive, and then coated with a final layer of sand-cement render and glass fibre reinforcement.

Alternative Fuels for Particulate Control in CI Engines

It is widely known that diesel combustion in a compression ignition (CI) engine produces and emits a significant amount of particulate matter (PM) which contributes to degradation in both health and environment. The origin of the soot formation depends on several factors, however, the main source of the soot emissions is the combustion of the diesel fuel itself. To circumvent this issue, studies hIt is widely known that diesel combustion in a compression ignition (CI) engine produces and emits a significant amount of particulate matter (PM) which contributes to degradation in both health and environment. The origin of the soot formation depends on several factors, however, the main source of the soot emissions is the combustion of the diesel fuel itself. To circumvent this issue, studies h

Unifying first-principles and model approaches for strongly correlated materials : Interplay between long- and short-range correlations

Fysik handlar om att försöka förstå hur världen omkring oss fungerar utifrån vissa grundläggande principer. Fasta tillståndets fysik fokuserar på de fasta material vi har omkring oss. Dessa material har olika strukturer beroende på vilka grundämnen de är uppbyggda av och hur de har bildats. Om en gas av atomer kyls ner långsamt tenderar atomerna att ordna sig i specifika regelbundna mönster, så kaIn materials with open 3$d$ and 4$f$ shells the valence electrons are relatively localized around the atoms which leads to large electron-electron correlations. These, so called strongly correlated materials, exhibit many intriguing properties such as high $T_c$ superconductivity, colossal magneto-resistance and heavy fermion behaviour. The strong electron-electron correlations make these material