Introduction: Direct oral anticoagulants (DOACs) have been proven non-inferior or superior to warfarin in preventing stroke and systemic embolism, with a lower risk of major hemorrhage, in patients with non-valvular atrial fibrillation (NVAF). We sought to investigate whether effectiveness and safety differs among apixaban, rivaroxaban and dabigatran. Materials and methods: Patients with newly ini

Background: Endocrine disrupting chemicals (EDCs) are xenobiotics with the ability to interfere with hormone action, even at low levels. Prior environmental epidemiology studies link numerous suspected EDCs, including phthalates and bisphenol A (BPA), to adverse neurodevelopmental outcomes. However, results for some chemicals were inconsistent and most assessed one chemical at a time. Objectives:

With this special issue Seismograf introduce you to ten new audio papers developed for the journal. The 10 audio papers are published in two volumes: The first, #22 Sonic Argumentation I, gathers scholars from artistic research in music, and the second, #23 Sonic Argumentation II, presents papers by scholars from ethnography, literature and sound studies.

Background: Off-target [18F]flortaucipir (tau) PET binding in the choroid plexus causes spill-in into the nearby hippocampus, which may influence the correlation between [18F]flortaucipir binding and measures of cognition. Previously, we showed that partial volume correction (combination of Van Cittert iterative deconvolution and HYPR denoising; PVC HDH) and manually eroding the hippocampus result

With this special issue Seismograf introduces you to ten new audio papers developed for the journal. The 10 audio papers are published in two volumes: The first, #22 Sonic Argumentation I, gathers scholars from artistic research in music, and the second, #23 Sonic Argumentation II, presents papers by scholars from ethnography, literature and sound studies.

With this special issue we are delighted to introduce you to ten new audio papers developed for Seismograf. The 10 audio papers are published in two volumes: The first, #22 Sonic Argumentation I, gathers scholars from artistic research in music, and the second, #23 Sonic Argumentation II, presents papers by scholars from ethnography, literature and sound studies.

Modern emerging technologies, such as additive manufacturing, bioprinting, and new material production, require novel metrology tools to probe fundamental high-speed dynamics happening in such systems. Here we demonstrate the application of the megahertz (MHz) European X-ray Free-Electron Laser (EuXFEL) to image the fast stochastic processes induced by a laser on water-filled capillaries with micr

The new European X-ray Free-Electron Laser (European XFEL) is the first X-ray free-electron laser capable of delivering intense X-ray pulses with a megahertz interpulse spacing in a wavelength range suitable for atomic resolution structure determination. An outstanding but crucial question is whether the use of a pulse repetition rate nearly four orders of magnitude higher than previously possible

Vi bör hålla fast vid dagens överskottsmål ett tag till. Först när vi kommit ned till 25 procents offentlig skuld kan vi våga överge överskottsmålet, skriver ekonomerna Fredrik N G Andersson och Lars Jonung, Lunds universitet.

User generated content (UGC) makes up a significant portion of Internet traffic. As opposed to other content, UGC has so far been left outside over-the-top providing network operators content distribution networks (telco-CDN) due to the difficulty in determining optimised placement of such content. The side effect of this is that UGC content is not placed close to end users and therefore occupy un

In the last decade the Internet as we know it has developed rapidly. With it music has been spread, consumed and absorbed in manners that ultimately questions both its status as well as its possibilities. In a digital age, does it make sense to think of music as progressing after certain inherent logics? Is music not enmeshed in our digital doings to such a degree that the entire foundation for ho

There is widespread concern regarding declines in bee populations given their importance for the functioning of both natural and managed ecosystems. An increasing number of studies find negative relations between bee species richness and simplification of agricultural landscapes, but the role of land-use intensity and its relative importance compared to landscape simplification remain less clear.

BACKGROUND: Enthesitis is one of the psoriatic arthritis (PsA) domains. Patients with enthesitis are associated with worse outcomes than those without enthesitis. The effect of secukinumab on the resolution of enthesitis in patients with PsA was explored using pooled data from the FUTURE 2 and 3 studies. METHOD: Assessments of enthesitis through week 104 used the Leeds Enthesitis Index. These post

Flyktingar, speciellt de som varit utsatta för tortyr och annan form av organiserat våld, upplever ofta en rad olika svårigheter, inklusive posttraumatiskt stressyndrom (PTSD), depression och somatiska symtom, särskilt smärta. Multidisciplinär behandling har utvecklats för att handskas med denna komorbiditet hos flyktingar, som har påvisat medelhöga effekter.Det huvudsakliga syftet med denna avhanRefugees, particularly those exposed to torture and other forms of organized violence, often experience a wide range of difficulties, including posttraumatic stress disorder (PTSD), depression, and somatic disturbances, particularly pain. Multimodal treatments have been developed to target this comorbidity in refugees, with evidence suggesting they are moderately effective.The overall aim of this

Plants respond to insect infestation with defenses targeting insect eggs on their leaves and the feeding insects. Upon perceiving cues indicating imminent herbivory, such as damage-induced leaf odors emitted by neighboring plants, they are able to prime their defenses against feeding insects. Yet it remains unknown whether plants can amplify their defenses against insect eggs by responding to cues

Pseudomonas aeruginosa efficiently adheres to human tissues, including the lungs and skin, causing infections that are difficult to treat. Laminin is a main component of the extracellular matrix, and in this study we defined bacterial laminin receptors on P. aeruginosa. Persistent clinical P. aeruginosa isolates from patients with cystic fibrosis, wounds or catheter-related urinary tract infection

Extracellular vesicle release is a wide-spread and broadly important phenomenon in bacteria. However, not much is known about the mechanism of vesicle release in Gram-positive bacteria. Observations of polarly growing Streptomyces venezuelae by live cell time-lapse imaging reveal release of extracellular membrane vesicles from tips of vegetative hyphae. Vesicle extrusion is associated with spontan