Protein C inhibitor (PCI) is a 57-kDa glycoprotein that exists in many tissues and secretions in human. As a member of the serpin superfamily of proteins it displays unusually broad protease specificity. PCI is implicated in the regulation of a wide range of processes, including blood coagulation, fertilization, prevention of tumors and pathogen defence. It has been reported that PCI isolated from

A coated hollow core microsphere is introduced as a novel target in ultra-intense laser-matter interaction experiments. In particular, it facilitates staged laser-driven proton acceleration by combining conventional target normal sheath acceleration (TNSA), power recycling of hot laterally spreading electrons and staging in a very simple and cheap target geometry. During TNSA of protons from one a

Cannulation of the papilla vateri represents an enigmatic first step in endoscopic retrograde cholangiopancreaticography (ERCP). In light of falling numbers of (diagnostic) ERCP and novel techniques, e. g. short-wire system, we were interested in the approach novice and experienced endoscopist are taking; especially, what makes a papilla difficult to cannulate and how to approach this. We devised

Utilizing semiconductor nanowires for (opto)- electronics requires exact knowledge of their current−voltage properties. We report accurate on-top imaging and I−V characterization of individual as-grown nanowires, using a subnanometer resolution scanning tunneling microscope with no need for additional microscopy tools, thus allowing versatile application. We form Ohmic contacts to InP and InAs nan

OBJECTIVE: To compare measurements of the arterial blood volume (aBV), a perfusion parameter calculated from arterial spin labelling (ASL), and cerebral blood volume (CBV), calculated from dynamic susceptibility contrast (DSC) MRI. In the clinic, CBV is used for grading of intracranial tumours. MATERIALS AND METHODS: Estimates of aBV from the model-free ASL technique quantitative STAR labelling of

Stable isotope analyses of tissues have been used to help delineate natal regions and routes of migratory animals. The foundations of such studies are isotopic gradients or differences representing geographic regions and habitat used by the organism that are retained in selected tissues. We sampled peacock butterflies Inachis io on a regional level in southern Sweden to study natural variation and

This article presents a research agenda about waste management from the perspective of management and organization studies. The agenda suggests that scholars should draw upon research on waste governance, lean management, the circular economy, and sustainable consumption. It also suggests, in a crossdisciplinary spirit, that scholars should heed research on waste within other social sciences and t

The discovery that paracetamol is metabolized to the potent TRPV1 activator N-(4-hydroxyphenyl)-5Z, 8Z, 11Z, 14Z-eicosatetraenamide (AM404) and that this metabolite contributes to paracetamol's antinociceptive effect in rodents via activation of TRPV1 in the central nervous system (CNS) has provided a potential strategy for developing novel analgesics. Here we validated this strategy by examining

In order to deliver innovative and cost-effective IP multimedia applications over mobile devices, there is a need to develop a unified service platform for the future mobile Internet referred as the Next Generation (NG) all-IP network. It is convincingly demonstrated by numerous recent studies that modern multimedia network traffic exhibits long-range dependence (LRD) and self-similarity. These ch

Activation of thrombin is a critical determinant in many physiological and pathological processes including haemostasis and inflammation. Under physiological conditions many of these functions are involved in wound healing or eradication of an invading pathogen. However, when activated systemically, thrombin can contribute to severe and life-threatening conditions by causing complications such as

Synthesis gas generated by the gasification of nitrogen-containing hydrocarbons will contain ammonia. This is a catalyst poison and elevated levels of nitrogen oxides (NOX) will be produced if the synthesis gas is combusted. This paper presents a study of the selective oxidation of ammonia in reducing environments. The concept is the same as in traditional selective catalytic reduction, where NOX

Electrical machines with distributed concentrated windings are challenging the selection of the soft magnetic materials due to stator design and power conversion efficiency. A shorter magnetisation path and relatively high magnetisation frequency establish a good potential for low permeability soft magnetic materials with low power losses in the core. The focus of this article is on the analysis o

Abstract in Undetermined A conceptually novel prosthesis consisting of a mechatronic hand, an electromyographic classifier, and a tactile display has been developed and evaluated by addressing problems related to controllability in prosthetics: intention extraction, perception, and feeling of ownership. Experiments have been performed, and encouraging results for a young transradial amputee are re

The evidence for the existence of a chemical mechanism in surface-enhanced resonance Raman scattering (SERRS) of rhodamine 6G (R6G) adsorbed on colloidal silver excited at 1064 nm is reported on the basis of experimental and theoretical analyses. A weak absorption peak at around 1060 nm for R6G-functionalized silver nanoparticles was observed, which is not present in the individual spectra of R6G

Lina Sandell-Berg. Hennes liv, tro, karriär och livsverk. Feminsitiskt symbolspråk i psalmerna.

Lipid A (a hexaacylated 1,4' bisphosphate) is a potent immune stimulant for TLR4/MD-2. Upon lipid A ligation, the TLR4/MD-2 complex dimerizes and initiates signal transduction. Historically, studies also suggested the existence of TLR4/MD-2-independent LPS signaling. In this article, we define the role of TLR4 and MD-2 in LPS signaling by using genome-wide expression profiling in TLR4- and MD-2-de

Context:The cardiac natriuretic peptides are involved in blood pressure regulation, and large cross-sectional studies have shown lower plasma levels of N-terminal pro-natriuretic peptide levels [N-terminal atrial natriuretic peptide (N-ANP) and N-terminal brain natriuretic peptide (N-BNP)] in patients with insulin resistance, obesity, and diabetes.Objective:In this study, we prospectively tested w