Laschiatrion (1), a new antifungal antibiotic, was isolated from fermentations of Favolaschia sp. 87129. (1) exhibits broad in vitro activity against several human pathogens while no antibacterial and cytotoxic activities could be detected. The structure was elucidated by spectroscopic techniques. As to our knowledge laschiatrion possesses a new steroid skeleton.

The burden of caregivers of patients suffering from of Alzheimer type dementia (DAT) and vascular dementia (VD) was analysed at the critical time, the “breaking-point”, when home care becomes insufficient and/or inadequate and the caregiver burden has probably reached its upper limit. Primary family caregivers of 39 DAT and 40 VD patients who were being considered for relocation into group-living

Objectives. To investigate whether any variables in a health-screened population study were associated with later developnent of large abdominal aortic aneurysms (AAA). Setting. Malmo, Southern Sweden. Material and methods. Within the Malmo Preventive Study 22,444 men and 10,982 women were investigated between 1974 and 1991. The mean age at the health screening was 43.7 years. Results. After a med

Here, we review the use of actin-based motors, (myosins; e.g., the molecular motor of muscle) in. nanotechnology. The review starts from the viewpoints of the molecular motors as being important devices responsible of cargo transportation in the cell and end in discussions about their employment in nanotechnological applications. First, we describe basic biophysics of the myosin motors with focus

Hip fracture is the most serious and resource consuming consequence of osteoporosis. All patients need operation and hospital treatment which gives a great health economic impact. The two main types of hip fracture are cervical (femoral neck, intracapsular) and trochanteric (extra capsular). For the displaced cervical fractures the blood circulation to the femoral head is more or less damaged whic

The aim of the present study was to develop a method for generation of dimethylbenzylamine (DMBA) atmospheres in an exposure chamber and to investigate the possibility of using urinary DMBA metabolites for biological monitoring of exposure to DMBA. A DMBA atmosphere was generated by use of the gas-permeation principle. Six healthy male volunteers were exposed for 8 h to DMBA at air levels of 20, 4

Popular Abstract in Swedish Denna doktorsavhandling i ämnet pedagogik utgör en analys av effekter av den pågående kulturella globaliseringen genom att granska två internationella magisterprogram vid Lunds universitet. Studiens syfte är att spåra mönster i en bärande pedagogisk idé för överföring av ett interkulturellt tänkande i tvärkulturella möten genom att utforska, beskriva och försöka förstå The present study is designed to analyze the effects of the ongoing cultural globalization. It utilizes as its empirical setting two special programmes called the International Master's Programme (the IMP,) directed by Lund University in Sweden. The aim of the study is to infer a pedagogic idea for intercultural transmission through cross-cultural encounters by exploring, describing, and comprehen

For the purpose of this deactivation study, Pt- and vanadia supported catalysts were used. The catalysts have been exposed to aerosol particles of inorganic salts, with high- or low melting points. The average diameter of the generated salt particle was kept constant at around 70 nm. The aerosol particle penetration depth for the samples exposed to potassium salt, was 1 μm as measured by scanning

Infection with Vibrio cholerae is a significant problem in manydeveloping countries. Cultivation of Vibrio cholerae is used inproduction of CTB, which is a component in a cholera vaccine. Fed - batch cultivations with V. cholerae in defined mediahave been conducted and reproducible results were obtained. A probing feeding strategy developed by Åkessonfor E. coli cultivations has been tested.The pr

Objective-The neuropeptide substance P (SP) is an inducer of neurogenic inflammation and bone resorption in the middle ear. Resorption of the bone tissue structures surrounding the middle ear cavity is a distinct feature of the initial stage of acute otitis media (AOM), which may be due to nerve fiber release of SP. Material and Methods-To investigate possible release of SP in the middle ear mucos

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In vitro tests are commonly employed to assess nebulizer performance. Whether the square or sine waveforms employed during in vitro tests could alter the nebulizer performance compared to that observed when a patient breathes through the nebulizer is debatable. Accordingly, the aim of this in vitro study was to compare the rates of delivery from nebulizers with simulated human breathing patterns t

Popular Abstract in Swedish De skånska godsen har genom århundradena inte bara utgjort ett spektakulärt inslag i landskapsbilden, de har också varit centrum för politisk maktutövning och jurisdiktion. I denna bok kartläggs och analyseras de skånska godsens ekonomiska och arbetsorganisatoriska utveckling från dansk tid till 1800-talets andra hälft. Utvecklingen vid nio gods uppmärksammas i fallstudThe aim of this study is to systematically survey and analyse the Scanian manors’ economic and labour organisational development from the province’s Danish times to the middle of the nineteenth century. In this thesis the various surveys provides some clear results that make it possible to generalise the Scanian estate development. Manors were generally large at the end of the the seventeenth cent

The thesis deals with determination of the post peak behaviour of wood in pure tension and pure shear. Furhermore, the "Fictitious Crack Model" (FCM), which is a nonlinear fracture mechanics model ; originally developed for description of crack propagation in concrete, is employed to demonstrate the advantages of non linear fracture mechanics. A testing arrangement is presented with which the comp

Two new vectors are described, the expression vector pB3 PGK and the CRE recombinase vector pCRE3. The pB3 PGK has a zeocin-selectable marker flanked by loxP sequences and an expression cassette consisting of the strong PGK1 promoter and the GCY1 terminator. The S. cerevisiae genes RKI1, RPE1, TAL1 and TKL1 were cloned in pB3 PGK and integrated in the locus of the respective gene, resulting in ove