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Comparison of EASI-derived 12-lead electrocardiograms versus paramedic-acquired 12-lead electrocardiograms using Mason-Likar limb lead configuration in patients with chest pain

Introduction: Monitoring of serial 12-lead electrocardiogram (ECG) recordings is the accepted requirement for prehospital data acquisition in patients with chest pain. The purpose of this study was to determine whether waveforms and clinical triage decisions are similar for EASI-derived ECGs and paramedic-acquired 12-lead ECGs using Mason-Likar limb lead configuration when compared with standard 1

C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1 alpha gene define HIF-1 alpha protein expression in non-small cell lung cancer

Objectives: In this study, we investigated whether polymorphisms of the HIF-1 alpha gene may account for the patterns of HIF-1 alpha protein expression in non-small cell lung carcinomas (NSCLC) and the expression of HIF-1 alpha down-stream proteins. Methods: Specific HIF-1 alpha polymorphisms were assessed in a series of patients with NSCLC: (a) the C to T transition at nucleotide 1744 (position 2

Nonionic polymers and surfactants: Temperature anomalies revisited

In view of a rapidly increasing importance in applications, as well as significant fundamental observations, the temperature anomalies displayed by several oxyethylene compounds, including poly(ethylene glycol), and oxyethylene surfactants and copolymers continue to create interest but also controversies. Here we review a wide range of experimental observations and present the different theoretica

Annual screening detects celiac disease in children with type 1 diabetes

Objective: To investigate the prevalence of celiac disease (CD) in a cohort of type 1 diabetes mellitus (T1DM) children and adolescents at the time of clinical diagnosis and to evaluate the screening procedure and possible role of human leukocyte antigen (HLA)-DQ during a 5-yr follow-up. Research design and methods: The study group was a cohort of 300 newly diagnosed T1DM children and youths young

Short-term dynamics of abiotic and biotic soil (CO2)-C-13 effluxes after in situ (CO2)-C-13 pulse labelling of a boreal pine forest

P>Physical diffusion of isotopic tracers into and out of soil pores causes considerable uncertainty for the timing and magnitude of plant belowground allocation in pulse-labelling experiments. Here, we partitioned soil CO2 isotopic fluxes into abiotic tracer flux (physical return), heterotrophic flux, and autotrophic flux contributions following (CO2)-C-13 labelling of a Swedish Pinus sylvestris f

Testing hypotheses of trophic level interactions: a boreal forest ecosystem

Models of community organization involve variations of the top-down (predator control) or bottom-up (nutrient limitation) hypotheses. Verbal models, however, can be interpreted in different ways leading to confusion. Therefore, we predict from first principles the range of possible trophic level interactions, and define mathematically the instantaneous effects of experimental perturbations. Some o

Glucose-stimulated insulin secretion correlates with beta-cell lipolysis.

Background and aims: Lipids are needed for optimal glucose-stimulated insulin secretion (GSIS), and long-chain acyl-CoA (LC-CoA) has been suggested as one candidate molecule active as a lipidic coupling factor. LC-CoAs may be available to the beta-cell via uptake of circulating free fatty acids or from hydrolysis of intracellularly stored triglycerides. Inhibition of lipolysis in rat islets using

In vivo visualization of displacement-distribution-derived parameters in q-space imaging.

Objective This study aimed to explore the potential of in vivo q-space imaging in the differentiation between different cerebral water components. Materials and Methods Diffusion-weighted imaging was performed in six directions with 32 equally spaced q values and a maximum b value of 6600 s/mm2. The shape of the signal-attenuation curve and the displacement propagator were examined and compared

Array-based genotype-phenotype correlation in a case of supernumerary ring chromosome 12

Supernumerary ring chromosomes (SRC) account for approximately 10% of prenatal marker chromosomes and 60% of these SRCs are associated with an abnormal phenotype of the patient carrying them. SRCs have, with few exceptions, not been characterized at the molecular genetic level. Here, we present the first case of a SRC 12 thoroughly investigated with tiling resolution array-based comparative genomi

The added value of PMS2 immunostaining in the diagnosis of hereditary nonpolyposis colorectal cancer.

dentification and characterization of the genetic background in patients with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome is important since control programmes can in a cost-effective manner prevent cancer development in high-risk individuals. HNPCC is caused by germline mismatch repair (MMR) gene mutations and the genetic analysis of HNPCC therefore includes assessment of micro

The monarchy as a corporate brand - Some corporate communications dimensions

Purpose - The purpose of this paper is to examine the role of corporate communications on behalf of the monarchy as a corporate brand. Design/methodology/approach - Draws on the preliminary findings of a major study on monarchies. Findings - Argues that corporate communications is an important aspect of corporate brand management (especially in relation to constitutional monarchies). Research impl

The self-reported health condition of women after their participation in a stress management programme: a pilot study

From a public health perspective, it is important to develop effective measures to deal with stress which are based on the individual's participation, such as stress management provided in group sessions. Therefore, the aim of the present study was to compare and evaluate the self-reported health condition of women in terms of their general symptoms, stress and sense of coherence (SOC) after parti

Management of extra-articular disease manifestations in rheumatoid arthritis

Purpose of review To discuss the rationale for various treatment strategies in rheumatoid arthritis with extra-articular manifestations, and to review advances in understanding the impact of extra-articular rheumatoid arthritis and its management. Recent findings Recent epidemiologic studies of extra-articular rheumatoid arthritis manifestations have emphasized their major role as predictors of pr