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Clinical Value of RNA Sequencing–Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network—Breast Initiative
PurposeIn early breast cancer (BC), five conventional biomarkers—estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), Ki67, and Nottingham histologic grade (NHG)—are used to determine prognosis and treatment. We aimed to develop classifiers for these biomarkers that were based on tumor mRNA sequencing (RNA-seq), compare classification performance, a
Production of deuterons, tritons, He 3 nuclei, and their antinuclei in pp collisions at s =0.9, 2.76, and 7 TeV
Invariant differential yields of deuterons and antideuterons in pp collisions at s = 0.9, 2.76 and 7 TeV and the yields of tritons, He3 nuclei, and their antinuclei at s = 7 TeV have been measured with the ALICE detector at the CERN Large Hadron Collider. The measurements cover a wide transverse momentum (pT) range in the rapidity interval |y|
Statsvetenskapliga perspektiv
Mutations in the gene of the Gα subunit of the heterotrimeric G protein are the cause for brachytic1 semi-dwarf phenotype in barley and applicable for practical breeding
Background: Short-culm mutants have been widely used in breeding programs to increase lodging resistance. In barley (Hordeum vulgare L.), several hundreds of short-culm mutants have been isolated over the years. The objective of thepresent study was to identify the Brachytic1 (Brh1) semi-dwarfing gene and to test its effect on yield and malting quality.Results: Double-haploid lines generated throu
Measurement of differential cross-sections of a single top quark produced in association with a W boson at √s=13TeV with ATLAS
The differential cross-section for the production of a W boson in association with a top quark is measured for several particle-level observables. The measurements are performed using 36.1fb-1 of pp collision data collected with the ATLAS detector at the LHC in 2015 and 2016. Differential cross-sections are measured in a fiducial phase space defined by the presence of two charged leptons and exact
Absence of paired crossing in the positive parity bands of Cs 124
High-spin states in Cs124 were populated in the Ni64(Ni64,p3n) reaction and the Gammasphere detector array was used to measure γ-ray coincidences. Both positive- and negative-parity bands, including bands with chiral configurations, have been extended to higher spin, where a shape change has been observed. The configurations of the bands before and after the alignment are discussed within the fram
Response of submerged macrophyte communities to external and internal restoration measures in north temperate shallow lakes
Submerged macrophytes play a key role in north temperate shallow lakes by stabilizing clear-water conditions. Eutrophication has resulted in macrophyte loss and shifts to turbid conditions in many lakes. Considerable efforts have been devoted to shallow lake restoration in many countries, but long-term success depends on a stable recovery of submerged macrophytes. However, recovery patterns vary w
Vetenskaplig kunskap i politiken : En breddad diskussion och användning är nödvändig
Den politiska kontexten
Stakeholder Interaction in Research Processes : A Guide for Researchers and Research Groups
Administrative Cooperation in the Assessment and Recovery of Direct Tax Claims
The Outsider: your average Yakuza wouldn’t recognise himself in this movie
Perceptions of the EU’s Role in the Ukraine-Russian and the Israeli-Palestinian conflicts: A biased mediator?
This article focuses on how the European Union's (EU) mediation activities during the Russia-Ukraine and Israel-Palestine conflicts are perceived by local elites. Our analysis is based on recent interviews with decision makers in Ukraine, Israel and Palestine. Consistent with this special issue, we investigate perceptions of EU roles, strategies and effectiveness. We suggest that the EU's relation
On a journey with uncertain destination: Metaphors and images of the eu in russian and ukrainian media after brexit vote
The outcome of the British Brexit referendum sent shockwaves across Europe. It sent signals about the future of the European Union (EU), not only to the Member States but also to the surrounding world. How to characterize the EU after Brexit? We address this problematic by investigating the metaphors applied to the EU in the Russian and Ukrainian press in the first week after the referendum. We fi
The Role of Sparsely Distributed Representations in Familiarity Recognition of Verbal and Olfactory Materials
We present the generalized signal detection theory (GSDT), where familiarity is described by a sparse binomial distribution of binary node activity rather than by normal distribution of familiarity. Items are presented in a distributed representation, where each node receives either noise only, or signal and noise. An old response (i.e., a ‘yes’ response) is made if at least one node receives sign
Wide temperature range testing with sonoclot plateletfunction and ROTEM EXTEM/FIBTEM/APTEM test
Journal of Thrombosis and Haemostasis DOI: 10.1111/j.1538-7836.2011.04380
Barnet och Frälsningen : Rapport från ett forskningsprojekt på IPS 2011–2012
En populär-teologisk bearbetning av frågor som rör frälsning, försoning, tro, dop och pånyttfödelse ur ett klassiskt pentekostalt/baptistiskt perspektiv och med särskilt fokus på barn och barn-teologi.
Integrated Modelling of the Global Cobalt Extraction, Supply, Price and Depletion of Extractable Resources Using the WORLD6 Model
The global cobalt cycle in society was modelled using an integrated systems dynamics model, WORLD6, integrating several earlier system dynamics models developed by the authors. The COBALT sub-model was used to assess the long-term sufficiency of the available extractable cobalt and address the effect of different degrees of recycling on cobalt supply. The extraction of cobalt is mostly dependent o
A Simple System Dynamics Model for the Global Production Rate of Sand, Gravel, Crushed Rock and Stone, Market Prices and Long-Term Supply Embedded into the WORLD6 Model
A model for global supply of sand, gravel and cut stone for construction based on a system dynamics model was developed for inclusion in the WORLD6 model. The Sand-Gravel-Stone model simulates production and market supply, demand and price for natural sand and gravel, sand and gravel from crushed rock and cut stone. The model uses market mechanisms where the demand is depending on population size,