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The history of scatter hoarding studies.

In this review, I will present an overview of the development of the field of scatter hoarding studies. Scatter hoarding is a conspicuous behaviour and it has been observed by humans for a long time. Apart from an exceptional experimental study already published in 1720, it started with observational field studies of scatter hoarding birds in the 1940s. Driven by a general interest in birds, sever

Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia

Background High-resolution genomic microarrays enable simultaneous detection of copy-number aberrations such as the known recurrent aberrations in chronic lymphocytic leukemia [del(11q), del(13q), del(17p) and trisomy 12], and copy-number neutral loss of heterozygosity. Moreover, comparison of genomic profiles from sequential patients' samples allows detection of clonal evolution. Design and Metho

Rat Multipotent Mesenchymal Stromal Cells Lack Long-Distance Tropism to 3 Different Rat Glioma Models

BACKGROUND: Viral gene therapy of malignant brain tumors has been restricted by the limited vector distribution within the tumors. Multipotent mesenchymal stromal cells (MSCs) and other precursor cells have shown tropism for gliomas, and these cells are currently being explored as potential vehicles for gene delivery in glioma gene therapy. OBJECTIVE: To investigate MSC migration in detail after i

Who leads research productivity growth? Guidelines for R&D policy-makers

This paper evaluates to what extent policy-makers have been able to promote the creation and consolidation of comprehensive research groups that contribute to the implementation of a successful innovation system. Malmquist productivity indices are applied in the case of the Spanish Food Technology Program, finding that a large size and a comprehensive multi-dimensional research output are the key

Pressure Plate - för bestämning av kapillär stighöjd, porstorlek och kornstorlek hos porösa material

Med en s.k. Pressure Plate utrustning kan porstukturen hos porösa material undersökas. För grovporösa material, t.ex. olika jordarter, kan även kapillära stighöjden -”sugförmågan”- och kornstorleken bestämmas på ett enkelt sätt. Metoden går ut på att man gradvis pressar ut vatten ur ett vattenmättat prov genom att utsätta detta för stegvis ökat tryck. Det finns ett enkelt samband -Laplace´s lag- m

Coherence as a heuristic

The impossibility results of Bovens and Hartmann (2003) and Olsson (2005) call into question the strength of the connection between coherence and truth. As part of the inquiry into this alleged link, I define a notion of degree of truth-conduciveness, relevant for measuring the usefulness of coherence measures as rules-of-thumb for assigning probabilities in situations of partial knowledge. I use

Does spatial employment density spur inter-firm job switching?

Inter-firm job switching of workers is a much cited but seldom measured source of the productivity advantages of spatial employment density. It has been advanced as a conduit for localized knowledge flows as well as labor market matching efficiency. Using a matched employer-employee dataset for Sweden, we estimate the influence spatial employment density has on the probability of inter-firm job sw

Evaluation of the aldose reductase inhibitor fidarestat on ischemia-reperfusion injury in rat retina

This study evaluated the effects of retinal ischemia-reperfusion (IR) injury and pre-treatment with the potent and specific aldose reductase inhibitor fidarestat on apoptosis, aldose reductase and sorbitol dehydrogenase expression, sorbitol pathway intermediate concentrations, and oxidative-nitrosative stress. Female Wistar rats were pre-treated with either vehicle (N-methyl-D-elucamine) or fidare

Effects of Salts on Internal DNA Pressure and Mechanical Properties of Phage Capsids.

Based on atomic force microscopy nanoindentation measurements of phage λ, we previously proposed a minimal model describing the effect of water hydrating DNA that strengthens viral capsids against external deformation at wild-type DNA packing density. Here, we report proof of this model by testing the prediction that DNA hydration forces can be dramatically decreased by addition of multivalent ion

The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length

Telomere length has been associated with risk of many cancers, but results are inconsistent. Seven single nucleotide polymorphisms (SNPs) previously associated with mean leukocyte telomere length were either genotyped or well-imputed in 11 108 case patients and 13 933 control patients from Europe, Israel, the United States and Australia, four of the seven SNPs reached a P value under .05 (two-side

A Radio Frequency Single-Electron Transistor Based on an InAs/InP Heterostructure Nanowire.

We demonstrate radio frequency single-electron transistors fabricated from epitaxially grown InAs/InP heterostructure nanowires. Two sets of double-barrier wires with different barrier thicknesses were grown. The wires were suspended 15 nm above a metal gate electrode. Electrical measurements on a high-resistance nanowire showed regularly spaced Coulomb oscillations at a gate voltage from -0.5 to

FDG-PET in Cervical Cancer - Translational Studies

Popular Abstract in Swedish Livmoderhalscancer är den näst vanligaste cancerformen att drabba kvinnor. Behandlingen baseras på vilket stadium sjukdomen befinner sig i och innebär en avsevärd risk för biverkningar. FDG-PET är en undersökningsmetod som kan visualisera områden i kroppen med ökat sockerupptag. Cancerceller har en kraftigt ökad omsättning av socker och därmed kan tumörer avbildas med FCervical cancer is the second most common cancer in females. The treatment, based on clinical FIGO stage, carries a significant risk of side effects. FDG-PET enables non-invasive studies of glucose metabolism. Cancer cells show an increased glucose uptake and metabolism that can be visualised and further analysed. The aims of this thesis were to evaluate FDG-PET in the clinical management of cerv

D-arabinitol in the diagnosis of invasive candidiasis

Popular Abstract in Swedish Invasiv candidiasis är en allvarlig jästsvampinfektion hos redan svårt sjuka patienter och denna infektion har ökat under de senaste årtiondena. Blododling, som ärreferensdiagnostisk metod för denna infektion, har relativt låg känslighet liksom detektion av Candidaspecifika antikroppar och antigener. Utvecklingen av PCR baserade diagnostik går långsamt och det saknas stInvasive candidiasis (IC) is a serious condition and timely diagnosis with early initiation of antifungal therapy is imerative for improving outcomes. Arabinitol is a sugar alcohol with two stereoisomers, D-arabinitol (DA) and L-arabintiol (LA). Several pathogenic Candida species produce DA in vitro and high DA levels have been detected in serum and urine in patients with IC. Renal dysfunction aff

Why do Manduca sexta feed from white flowers? Innate and learnt colour preferences in a hawkmoth

Flower colour is an important signal used by flowering plants to attract pollinators. Many anthophilous insects have an innate colour preference that is displayed during their first foraging bouts and which could help them locate their first nectar reward. Nevertheless, learning capabilities allow insects to switch their colour preferences with experience and thus, to track variation in floral nec