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Maintenance and Commitment of Hematopoietic Progenitors: Role of flt3, c-kit and c-mpl

The need for red blood cells to transport oxygen and CO2, blood platelets to stop bleedings, and neutrophils, macrophages, B- and T-cells for host defense, is a prerequisite for life. These mature blood cells have a limited life span and are thus constantly replenished by an enormous cell production (estimated to 1012 cells per day) which primarily takes place in the bone marrow (BM). Mature blood

How much PAR to bring to the party?

Reducing Peak-to-Average power Ratios (PAR) is an established research topic that has now begun to find its way into products. This gives rise to new questions of dimensioning. Here we address how much PAR reduction that should be applied in a practical system. We demonstrate that the amount of PAR reduction can be found with the appropriate system models. This is applied to the tonereservation PA