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Environmental and anthropogenic correlates of migratory speeds among Atlantic salmon smolts

Dams, weirs, and hydropower facilities are often cited as migratory barriers which impart significant reductions in fitness among migratory fish species. Even where upstream and downstream passage options are available, barrier passage can still often result in energetic or physical costs which compound delays or cause mortality. Past studies have identified variables associated with such fitness

Australian Bogong moths Agrotis infusa (Lepidoptera : Noctuidae), 1951–2020: decline and crash

The Bogong moth Agrotis infusa is well known for its remarkable long-distance migration – a return journey from the plains of southeast Australia to the Australian Alps – as well as for its cultural significance for Indigenous Australians. Each Spring, as many as four billion moths are estimated to arrive in the Australian Alps to aestivate in cool mountain caves and in boulder fields, bringing wi

The changing marketing orientation within the business model of an international retailer–IKEA in China over 10 years

The paper reports an interview-based study that considers market driving and market-driven activities within the disaggregated components of the business model. The empirical study is of IKEA in China over a 10 year period. Market orientation is considered as a position on a continuum rather than as binary positions. The components of the business model are developed from the Osterwalder and Pigne

Autoimmune disease is associated with a lower risk of progression in monoclonal gammopathy of undetermined significance

Objectives and methods: We conducted a population-based study including 19 303 individuals diagnosed with MGUS in Sweden from 1985 to 2013, with the aim to determine whether a prior history of autoimmune disease, a well-described risk factor for MGUS is a risk factor for progression of MGUS to multiple myeloma (MM) or lymphoproliferative diseases (LPs). Using the nationwide Swedish Patient registr

Apolipoprotein E interferes with IAPP aggregation and protects pericytes from IAPP-Induced Toxicity

Apolipoprotein E (ApoE) has become a primary focus of research after the discovery of its strong linkage to Alzheimer’s disease (AD), where the ApoE4 variant is the highest genetic risk factor for this disease. ApoE is commonly found in amyloid deposits of different origins, and its interaction with amyloid-β peptide (Aβ), the hallmark of AD, is well known. However, studies on the interaction of A

Functional outcomes associated with varying levels of targeted temperature management after out-of-hospital cardiac arrest — An INTCAR2 registry analysis

Introduction: Targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) has been recommended in international guidelines since 2005. The TTM-trial published in 2013 showed no difference in survival or neurological outcome for patients randomised to 33 °C or 36 °C, and many hospitals have changed practice. The optimal utilization of TTM is still debated. This study aimed to

A systemic overreaction to years versus decades of warming in a subarctic grassland ecosystem

Temperature governs most biotic processes, yet we know little about how warming affects whole ecosystems. Here we examined the responses of 128 components of a subarctic grassland to either 5–8 or >50 years of soil warming. Warming of >50 years drove the ecosystem to a new steady state possessing a distinct biotic composition and reduced species richness, biomass and soil organic matter. However,

Obstacle Comparisons to Achieving Distance Learning and Applying Electronic Exams during COVID-19 Pandemic

This study aims to identify obstacles and barriers to achieving quality distance learning and the use of electronic exams, comparing them to pursue success in the distance education system during the coronavirus pandemic (COVID-19). It also aimed to determine the similarity and differences between the two main components of distance education. This is based on a sample of evaluations from professo

Incidence of distal radius fracture in a general population in southern Sweden in 2016 compared with 2001

Summary: In this population-based study, we compared the incidence of distal radius fracture in 2016 with that in the same region’s adult general population in 2001 using radiographs to identify fracture cases. We showed that the incidence decreased by 24% in 2016 compared with 2001 indicating an important development. Introduction: We conducted an epidemiological study on residents of northeaster

Processes of ‘hummocky moraine’ formation in the Gaick, Scotland : insights into the ice-marginal dynamics of a Younger Dryas plateau icefield

Younger Dryas ice-marginal (‘hummocky’) moraines in Scotland represent valuable terrestrial archives that can be used to obtain important information on ice-marginal dynamics and glacier thermal regimes during a period of rapid climatic change. In this paper, we present detailed sedimentological studies of Younger Dryas ice-marginal moraines in the Gaick, central Scotland, the former site of a spa

EpilepsyGAN : Synthetic Epileptic Brain Activities with Privacy Preservation

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can also be life-threatening. Modern systems monitoring elec-troencephalography (EEG) signals are being currently developed with the view to detect epileptic seizur

Resonant inelastic x-ray scattering on CO2 : Parity conservation in inversion-symmetric polyatomics

Resonant inelastic x-ray scattering (RIXS) spectra excited at the oxygen K edge of CO2 are presented and discussed. Although excitation from a gerade initial state to the intermediate 1s-1π∗ state breaks the inversion symmetry due to strong vibronic coupling, RIXS excited at the corresponding resonance exclusively populates gerade vibrations in the gerade electronic ground state. This observation

What do we want to know about reshoring? Towards a comprehensive framework based on a meta-synthesis

This study aims to develop a framework for reshoring research, specifying the aspects encompassing a full case description. The article reports an analysis of existing case-based research focusing on manufacturing reshoring and the previous offshoring events, with the aim to advance the knowledge within the field through an accumulation process. The selected methodology to achieve this purpose is

Experiences of participation in supervised group exercise among pregnant women with depression or low psychological well-being : A qualitative descriptive study

Objective: To explore experiences with supervised group exercise during pregnancy in women with depression or low psychological well-being. Design: A qualitative descriptive study based on semi-structured, individual, in-depth interviews analyzed by means of thematic analysis. Setting: The Department of Obstetrics, Rigshospitalet, Copenhagen University Hospital, Denmark. Participants: Through a pu

Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug

Human exposure to carbamates and organophosphates poses a serious threat to society and current pharmacological treatment is solely targeting the compounds' inhibitory effect on acetylcholinesterase. This toxicological pathway, responsible for acute symptom presentation, can be counteracted with currently available therapies such as atropine and oximes. However, there is still significant long-ter

Developing ActivABLES for community-dwelling stroke survivors using the Medical Research Council framework for complex interventions

Background: Novel technical solutions are called for to promote home-based exercise among community-dwelling stroke survivors supported by their caregivers. Lack of resources and knowledge about how to accomplish it, has been demonstrated. The objective of this study is to describe in detail the development of ActivABLES, a technical intervention to promote home-based exercise and physical activit

The social context of nearest neighbors shapes educational attainment regardless of class origin

We study the association between sociospatial neighborhood conditions throughout childhood and educational attainment in adulthood. Using unique longitudinal microdata for a medium-sized Swedish town, we geocode its population at the address level, 1939 to 1967, and link individuals to national registers, 1968 to 2015. Thus, we adopt a long-term perspective on the importance of nearby neighbors du

Unity Makes Strength : Exploring Intraspecies and Interspecies Toxin Synergism between Phospholipases A2 and Cytotoxins

Toxin synergism is a complex biochemical phenomenon, where different animal venom proteins interact either directly or indirectly to potentiate toxicity to a level that is above the sum of the toxicities of the individual toxins. This provides the animals possessing venoms with synergistically enhanced toxicity with a metabolic advantage, since less venom is needed to inflict potent toxic effects

Pre-treatment allostatic load and metabolic dysregulation predict SSRI response in major depressive disorder : A preliminary report

BackgroundMajor depressive disorder (MDD) is associated with increased allostatic load (AL; a measure of physiological costs of repeated/chronic stress-responding) and metabolic dysregulation (MetD; a measure of metabolic health and precursor to many medical illnesses). Though AL and MetD are associated with poor somatic health outcomes, little is known regarding their relationship with antidepres