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Basic fibroblast growth factor for stimulation of bone formation in osteoinductive and conductive implants

Popular Abstract in Swedish Basic Fibroblast Growth Factor (bFGF) är en av flera tillväxtfaktorer som finns lagrad i benvävnaden. bFGF framkallar celldelning och tillväxt hos många olika celltyper, däribland benceller (osteoblaster) och broskceller. bFGF kan stimulera till nybildning av blodkärl och även benvävnad. I denna avhandling undersökes om utifrån tillfört bFGF kan öka benbildning och vävnBasic Fibroblast Growth Factor (bFGF) is one of the endogenous factors found in bone matrix. bFGF is a mitogen for many cell types, including osteoblasts and chondrocytes. It can stimulate angiogenesis and osteoblast gene expression. The purpose of this study was to investigate whether exogenous bFGF can stimulate the formation of bone in bone grafts and in a bone graft substitute. All experiments

Overexpression of the Ca2+-binding protein calreticulin in the endoplasmic reticulum improves growth of tobacco cell suspensions (Nicotiana tabacum) in high-Ca2+ medium

Calreticulin (CRT) is a eukaryotic, highly conserved, Ca2+-binding protein predominantly located in the endoplasmic reticulum (ER) lumen. In addition to being involved in the regulation of cellular Ca2+, calreticulin is a key quality control element during protein folding in the ER lumen. Tobacco (Nicotiana tabacum L.) suspension cells overexpressing a maize CRT (CRT1a) were used here to examine t

Biskopen visiterar. Den kyrkliga överhetens möte med lokalsamhället 1650-1760

Popular Abstract in Swedish Syftet med denna avhandling är att undersöka mötet mellan den kyrkliga överheten och de olika lokalsamhällena sådant som det tog sig uttryck vid de kyrkliga visitationerna. I fokus står biskopsvisitationerna men även de visitationer som prostarna genomförde tas upp till behandling. Undersökningsområdet är Växjö stift och den tidsmässiga avgränsningen är 1650-1760. De frThe aim of this thesis is to investigate the encounter of the ecclesiastical authorities with the local community, as reflected in the church visitations. The focus is on the bishops' visitations, but there is also a brief examination of the deans' visitations, which are used for a comparison of the two types of inspections. The geographical limit of the study is the diocese of Växjö in southern S

Slagen dam och tystnaden

I samband med att Kvinnofridsreformen i Sverige 1998 uppdrog regeringen åt brottsoffermyndigheten att undersöka mörkertalet i fråga om mäns våld mot kvinnor som ett komplement till den officiella statistik som brottsförebyggande rådet normalt svarade för. Ansvaret för studien tilldelades Eva Lundgren, professor i sociologi och Gun Heimer, överläkare och chef för RiksKvinnoCentrum. Tillsammans med

Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden

Objectives. To estimate the point prevalence (p.p.) of Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), polyarteritis nodosa (PAN) and Churg-Strauss syndrome (CSS) within a defined population in southern Sweden. Method. A cross-sectional p.p. study using multiple sources for case identification. The study area, a healthcare district around the city of Lund in southern Sweden (Mellers

Reincentivizing- a new theory of work and work absence

Background: Work capacity correlates weakly to disease concepts, which in turn are insufficient to explain sick leave behavior. With data mainly from Sweden, a welfare state with high sickness absence rates, our aim was to develop an explanatory theory of how to understand and deal with work absence and sick leave. Methods: We used classic grounded theory for analyzing data from >130 interviews wi

Event texture search for critical fluctuations in Pb plus Pb collisions

NA44 uses a 512 channel Si pad array covering 1.5 < eta < 3.3 to study charged hadron production in 158 A GeV Pb+Pb collisions at the CERN SPS. We apply a multiresolution analysis, based on a Discrete Wavelet Transformation, to probe the texture of particle distributions event-by-event, by simultaneous localization of features in space and scale. Scanning a broad range of multiplicities, we look f

Lactobacilli express cell surface proteins which mediate binding of immobilized collagen and fibronectin

Binding of immobilized collagen-I (Cn-I) and fibronectin (Fn) by Lactobacillus acidophilus CRL 639 depends on cell-surface proteins. Capsule formation during the stationary growth phase has a negative effect on adherence of Cn-I and Fn. However, cells from the exponential growth phase. which produce no capsule, exhibit maximal binding. Binding is sensitive to trypsin, proteinase K, pronase E, and

Photoemission study of GaAs (100) grown at low temperature

GaAs(100) layers grown by low-temperature (LT) molecular beam epitaxy were studied by means of valence-band and core-level photoelectron spectroscopy. Small differences were found between valence-band spectra from the LT layers and corresponding layers grown at high temperature. In the Ga 3d spectra a new component was found in the LT-GaAs. The relative intensity of this component was found to be

Decision Analysis in Fire Safety Engineering - Analysing Investments in Fire Safety

The application of decision analytical methods to the evaluation of investments in fire safety was investigated, particularly with the aim of being able to suggest a method for analysing a specific investment in fire safety for a specific factory. Attention was directed above all at the handling of cases of large epistemic uncertainty regarding both probabilities and utilities, Bayesian decision t

Resolving isospectral 'drums' by counting nodal domains

Several types of systems have been put forward during the past few decades to show that there exist isospectral systems which are metrically different. One important class consists of Laplace-Beltrami operators for pairs of flat tori in R-n with n >= 4. We propose that the spectral ambiguity can be resolved by comparing the nodal sequences (the numbers of nodal domains of eigenfunctions, arranged

Non-invasive measurements of longitudinal strain of the arterial wall

We have recently shown that there is a previous unknown longitudinal movement present in the arterial wall. The aim is now to investigate whether the longitudinal movement is associated with longitudinal strain of the arterial wall. The objective of this paper was to describe a new non-invasive ultrasonic technique that measures the longitudinal strain of arteries in human in-vivo. Results indicat

Understanding adherence to official guidelines on statin prescribing in primary health care-a multi-level methodological approach.

Objective: The aim was to investigate the role that municipalities and out-patient health care centres (HCCs) have in understanding adherence to official guidelines on statin prescribing. Our hypothesis was that after guideline publication, adherence to recommended statin prescription would increase and variance among HCCs and municipalities would decrease. Since multi-level regression analysis (M

Att leva med cancer som äldre - livskvalitet och upplevelse av mening

Hur påverkas livssituationen för äldre som drabbas av cancer? Oftast blir sjukdomen ytterligare en belastning i en redan komplex situation. I denna artikel sammanfattas resultat från en undersökning av en grupp äldre (över 75 år) personer med cancer. Livskvaliteten påverkades mest hos yngre äldre, men gruppen är heterogen och personerna kräver ett individuellt bemötande.

Diabetic retinopathy, visual acuity, and medical risk indicators: a continuous 10-year follow-up study in Type 1 diabetic patients under routine care

The objective of this study was to describe incidence and progression of diabetic retinopathy in relation to medical risk indicators as well as visual acuity outcome after a continuous follow-up period of 10 years in a Type 1 diabetic population treated under routine care. The incidence and progression of retinopathy and their association to HbA(1c), blood pressure, urinary albumin, serum creatini

Skuld och oskuld : barnamord och barnkvävning i rättslig diskurs och praxis omkring 1680–1800

Syftet med denna avhandling är att analysera hur berättelser om skyldiga och oskyldiga mödrar konstruerades under perioden ca. 1680-1800. De två brottskategorierna barnamord och barnkvävning har undersökts. Källmaterialet har huvudsakligen bestått av protokoll från hovrätten, underrätter och sockenstämmor. Jag har klarlagt vilka omständigheter som utreddes vid brottsutredningarna och fick betydelsThe objective of this thesis is to analyse how judicial texts concerning guilty and innocent mothers were constructed during the period of c. 1680-1800. The two crimes of infanticide and overlaying have been examined. Source materials have primarily consisted of proceedings from the appeals court, courts of first instance, and parish meetings. The aim has been to survey the judicial discourse, tha