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Angiogenesis is a prognostic indicator in primary breast cancer regulated by specific angiogenic factors and their receptors. Vascular endothelial growth factor-A (VEGF-A), so far considered the most important, acts through dimerization of the receptor VEGFR2/KDR within the receptor tyrosine kinase family of VEGF receptors. In order to study the interplay between VEGF-A and VEGFR2/KDR in breast ca
I rapporten beskrivs byggnadsfysikaliska mätningar i ett provhus med olika skalmurskonstruktioner. Mätningar har pågått under en 3-årsperiod och främst varit inriktade på fukt- och temperaturbetingelser i murverket, luftspalten, isoleringen och träreglarna.
Essä om författarens arbete med att restaurera och rekonstruera G W Pabsts stumfilmsklassiker Den glädjelösa gatan (Die Freudluse Gasse, 1925) och hur det påverkat synen på filmens historia och utveckling av berättartekniken.
The first results from the stopped beam RISING experimental campaign performed at the GSI laboratory in Darmstadt, Germany, are presented. RISING (Rare ISotope Investigations at GSI) constitutes a major new experimental program in European nuclear structure physics research aimed at using relativistic energy (typically around 1 GeV per nucleon) projectile fragmentation reactions to populate nuclei
OBJECTIVES: To analyse survival rates and the causes of death in a systemic sclerosis (SSc) population, and to evaluate the occurrence of fatal malignant neoplasms and their possible association with oral cyclophosphamide (CYC) treatment. METHODS: Survival was calculated for 249 SSc patients followed up for up to 13 years. Mean (SD) follow up was 5.8 (4.2) years. The 49 decreased patients were sub
Pancreatic islets have a central role in blood glucose homeostasis. In addition to insulin-producing beta-cells and glucagon-secreting alpha-cells, the islets contain somatostatin-releasing delta-cells(1). Somatostatin is a powerful inhibitor of insulin and glucagon secretion(2). It is normally secreted in response to glucose(3) and there is evidence suggesting its release becomes perturbed in dia
The thesis concerns risk and safety in manufacturing companies in a developing country. Risk and safety is viewed as integral to the social relations between management and labour. The Malaysian case presents a historical conjuncture of this conflict theme, which is very different from that of its Western genesis. On this basis, the primary objective of the thesis is defined as an effort to escape
The pheromone-mediated upwind flight of male turnip moths was observed in a flight tunnel at different times of day under conditions of a light-dark (LD) cycle, constant darkness (DD), and a shifted photoperiod. Under both LD and DD conditions, a significantly larger number of males flew to the pheromone during both the scotophase and the subjective scotophase than during the photophase and the su
The resonance lines of helium in the Sun are several times stronger than expected, relative to lines of other ions. To explore the origins of this "helium enhancement,'' we have studied data from the SUMER, CDS, MDI, and EIT instruments on the Solar and Heliospheric Observatory (SOHO). Time series data obtained in a quiet region and a coronal hole indicate that the spatio-temporal properties of th
Popular Abstract in Swedish Gastroesofageal refluxsjukdom innebär att maginnehåll backar (reflux) upp från magsäcken till matstrupen på ett onormalt sätt. Hos den friska individen finns flera mekanismer som skyddar matstrupen från reflux, vilket tydligt åskådliggörs av att man efter en måltid kan ställa sig upp och ner utan att föda backar upp i matstrupen. Vid refluxsjukdom föreligger defekter inEsophageal pH monitoring is important in the clinical management of patients with symptoms suggestive of gastroesophageal reflux disease (GERD), and in research aiming to clarify the mechanisms involved in the development of GERD complications. Catheter-based techniques for pH recording are uncomfortable, not well tolerated by all patients and cannot reliably measure acid exposure in the most dist
This thesis investigates a set of degree modifiers of adjectives common in spoken British English. The main focus of the study is on generalizable semantic and intonational features, but attention is also given to the use of the modifiers in authentic speech in terms of frequency, collocability and intonation. The study explores the semantic constraints that govern the relationship between degree
BACKGROUND: Thrombosis is one of the most important causes of morbidity in the medical field. Several independent in vitro studies have shown that the fibrinolytic process may be enhanced by ultrasound, but the effect of ultrasound on thrombus formation in vivo is unexplored. The present study was designed to investigate this matter. METHODS: In a blind randomized study, standardized arteriotomies
