Sökresultat

Filtyp

Din sökning på "*" gav 531169 sökträffar

Is the subarctic landscape still a carbon sink? Evidence from a detailed catchment balance

Climate warming raises the question whether high-latitude landscape still function as net carbon (C) sinks. By compiling an integrated C balance for an intensely studied subarctic catchment, we show that this catchment's C balance is not likely to be a strong current sink of C, a commonly held assumption. In fact, it is more plausible (71% probability) that the studied catchment functions as a C s

KIF5C S176 phosphorylation regulates microtubule binding and transport efficiency in mammalian neurons

Increased phosphorylation of the KIF5 anterograde motor is associated with impaired axonal transport and neurodegeneration, but paradoxically also with normal transport, though the details are not fully defined. JNK phosphorylates KIF5C on S176 in the motor domain; a site that we show is phosphorylated in brain. Microtubule pelleting assays demonstrate that phosphomimetic KIF5C (1-560)S176D associ

Investigation of ionization-induced electron injection in a wakefield driven by laser inside a gas cell

Ionization-induced electron injection was investigated experimentally by focusing a driving laser pulse with a maximum normalized potential of 1.2 at different positions along the plasma density profile inside a gas cell, filled with a gas mixture composed of 99%H2+1%N2. Changing the laser focus position relative to the gas cell entrance controls the accelerated electron bunch properties, such as

An information-based neural approach to constraint satisfaction

A novel artificial neural network approach to constraint satisfaction problems is presented. Based on information-theoretical considerations, it differs from a conventional mean-field approach in the form of the resulting free energy. The method, implemented as an annealing algorithm, is numerically explored on a testbed of K-SAT problems. The performance shows a dramatic improvement over that of

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases including cardiovascular diseases, diabetes, and cancer. Through genomewide association study of up to 30 884 adults of European ancestry from 21 studies, w

N-Ethylmaleimide Sensitive Factor (NSF) Inhibition Prevents Vascular Instability following Gram-Positive Pulmonary Challenge

BACKGROUND: The Acute Respiratory Distress Syndrome (ARDS), remains a significant source of morbidity and mortality in critically ill patients. Pneumonia and sepsis are leading causes of ARDS, the pathophysiology of which includes increased pulmonary microvascular permeability and hemodynamic instability resulting in organ dysfunction. We hypothesized that N-ethylmaleimide sensitive factor (NSF) r

Disturbance from roads negatively affects Andean condor habitat use

Human disturbance can be a severe problem for some animal species. Behavioural ecology theory predicts that sensitivity to mortality risks, and thereby to disturbance, will be related to life-history characteristics. Long-lived species with low reproductive rates are expected to have a high cost of predation and therefore avoid risks strongly. In this paper we quantify the effect of roads on the A

Identification of the MMRN1 binding region within the C2 domain of human factor V

In platelets, coagulation cofactor V is stored in complex with multimerin 1 in alpha-granules for activation- induced release during clot formation. The molecular nature of multimerin 1 factor V binding has not been determined, although multimerin 1 is known to interact with the factor V light chain. We investigated the region in factor V important for multimerin 1 binding using modified enzyme-li

Ru II wavelengths and energy levels derived by Fourier transform spectroscopy

The RuII spectrum emitted from a hollow cathode discharge has been recorded in the region 12500-55500cm(-1) (8000-1800Angstrom) using a Fourier transform spectrometer. 538 RuII lines have been measured with high accuracy (+/- 0.003-0.020cm(-1)). Improved energy level values have been derived from the lines and 17 new even levels have been found. The level structure has been interpreted by means of

Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions.

In vitro, expanded neurospheres exhibit multipotent properties and can differentiate into neurons, astrocytes and oligodendrocytes. In vivo, cells from neurospheres derived from mouse fetal forebrain have previously been reported to predominantly differentiate into glial cells, and not into neurons. Here we isolated stem/progenitor cells from E13.5 lateral ganglionic eminence (LGE), medial ganglio

Theoretical Atomic Spectroscopy of Earthbound and Stellar Plasma

Ljus är verkligen fantastiskt. Det kan ge oss känslomässiga upplevelser, som när det faller genom en trädkrona i en skog eller vid en blodröd fullmåne, men det gör det också möjligt för oss att uppfatta och förstå vår omgivning. Majoriteten av den information vi kan tillgodogöra oss om Universum, får vi genom det ljus som atomer och joner i olika kosmiska objekt sänder ut. Varje foton - den minstaMotivated by spectroscopic analysis of astrophysical and laboratory plasma, this thesis concerns the fundamental structure and spectral properties of atoms and their ions. The multiconfiguration Dirac-Hartree-Fock (MCDHF) method is used to predict the emission or absorption of radiation, by atomic systems in general, and of heavy and highly charged ions in particular.The first set of publications,

Adsorption studies of interaction between water-extractable nonstarch polysaccharides and prolamins in cereals

Adsorption of cereal storage protein and nonstarch polysaccharides onto methylated silica surfaces, as measured by ellipsometry, was used to study possible interactions between those components. All fractions, rye secalin, wheat gliadin, rye arabinoxylan, and wheat arabinogalactan peptide, were surface- oxylan and wheat arabinogalactan peptide on top of gliadin and secalin, respectively, indicated

Destroy what destroys the planet : Steering creative destruction in the dual crisis

In the contemporary dual crisis, economic crisis policies cannot be dealt with in isolation from the rampant and acute ecological crisis – and vice versa. In this article, we challenge the hegemonic positions in purported attempts to solve the crises so far: in the economic realm, the Keynesian episode of 2008–2009 as well as austerity policies, and with regard to the ecological crisis, ecologicalIn the contemporary dual crisis, economic crisis policies cannot be dealt with in isolation from the rampant and acute ecological crisis – and vice versa. In this article, we challenge the hegemonic positions in purported attempts to solve the crises so far: in the economic realm, the Keynesian episode of 2008–2009 as well as austerity policies, and with regard to the ecological crisis, ecological

Photoexcitation of excitons in self-assembled quantum dots

Using an approach of combining Fourier transform infrared spectroscopy with resonant illumination from a secondary external light source, we have measured the photocurrent (PC) for multiple layers of self-assembled InAs dots embedded in a matrix of InP. Without external illumination, we observe photoexcitation of electrons from bound states in the dots to the InP barrier. By additional illuminatio

A broadband laser plasma X-ray source for application in ultrafast chemical structure dynamics

A plasma source free from characteristic emission lines is described, based on laser irradiation of a water jet in a helium atmosphere. Various key aspects of the laser interaction are presented along with practical characterization of the observed isotropic ~4–10 keV x-ray emissions, measurements of which indicate subpicosecond duration. Observations are consistent with a vacuum heating plasma me

Optical monitoring of volcanic sulphur dioxide emissions - comparison between four different remote-sensing spectroscopic techniques

The emissions of sulphur dioxide from the Italian volcanoes Mt. Etna and Stromboli were studied in ship-borne underpasses of their plumes. Four different optical spectroscopy techniques were used and inter-compared. All techniques utilise the absorption signature of the gas in the wavelength region of around 300 nm. A differential absorption lidar was employed in active gas concentration assessmen

Landmark-Based Software for Anatomical Measurements: A Precision Study

The aim of this study was to develop a software program, called Landmarker, which would aid studies of complex anatomical morphometry by simplifying the manual identification of landmarks in 3D images. We also tested its precision on routine magnetic resonance imaging (MRI) scans. To understand human biological variation, there is a need to identify morphological characteristics from the exterior