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The micrometeorite flux to Earth during the Frasnian–Famennian transition reconstructed in the Coumiac GSSP section, France
We have reconstructed the distribution of extraterrestrial chrome spinels in a marine limestone section across the Frasnian–Famennian stratotype section at Coumiac in southern France, providing the first insights on the types of micrometeorites and meteorites that fell on Earth at this time. The data can test whether the small cluster of roughly coeval, large impact structures is related to an ast
Green industry development in different types of regions
At the regional level, the imperative of sustainable development often manifests itself in an emphasis on developing green industries. However, regions vary in their preconditions for achieving this. In this paper we link regional preconditions to various pathways for green industry development. This provides the foundation for identifying place-based policy implications for growing green industri
RIFM fragrance ingredient safety assessment, 4,8-dimethyl-4,9-decadienal, CAS Registry Number 71077-31-1
Polygenetic risk for coronary artery disease increases hospitalization burden and mortality
Background: Coronary artery disease (CAD) is a leading cause of death worldwide and increasing cost for society. Genome wide association studies (GWAS) have identified common variants associated with CAD. Combining single nucleotide polymorphisms (SNPs) into a genetic risk score (GRS) can estimate an individual's genetic burden. Objectives: To investigate whether GRS for CAD can predict hospitaliz
Missense mutations in the C-terminal portion of the B4GALNT2-encoded glycosyltransferase underlying the Sd(a−) phenotype
Sda is a high-frequency carbohydrate histo-blood group antigen, GalNAcβ1-4(NeuAcα2-3)Galβ, implicated in pathogen invasion, cancer, xenotransplantation and transfusion medicine. Complete lack of this glycan epitope results in the Sd(a−) phenotype observed in 4% of individuals who may produce anti-Sda. A candidate gene (B4GALNT2), encoding a Sda-synthesizing β-1,4-N-acetylgalactosaminyltransferase
Mapping spatio-temporal patterns and detecting the factors of traffic congestion with multi-source data fusion and mining techniques
The study focuses on mapping spatiotemporal patterns and detecting the potential drivers of traffic congestion with multi-source data. First, based on real-time traffic data retrieved from an online map, the k-means clustering algorithm was applied to classify the spatiotemporal distribution of congested roads. Then, we applied a geographical detector (Geo-detector) to mine the potential factors f
The mineralo-sphere – Succession and physiology of bacteria and fungi colonising pristine minerals in grassland soils under different land-use intensities
The mineralo-sphere is an important micro habitat in terrestrial ecosystems. How different groups of microorganisms colonise mineral surfaces and whether the level of grassland land-use intensity (LUI) modifies this micro-habitat is not well known, however. We exposed mesh containers filled with pristine soil minerals (illite/goethite) mixed with 13C labelled root litter of Dactylis glomerata and
Sex-specific difference in migration schedule as a precursor of protandry in a long-distance migratory bird
Protandry, the earlier arrival of males at the breeding grounds relative to females, is common in migratory birds. However, due to difficulties in following individual birds on migration, we still lack knowledge about the spatiotemporal origin of protandry during the annual cycle, impeding our understanding of the proximate drivers of this phenomenon. Here, we use full annual cycle tracking data o
Potential pitfalls of the early-time dynamics in two-dimensional electronic spectroscopy
Two-dimensional electronic spectroscopy, and especially the polarization-controlled version of it, is the cutting edge technique for disentangling various types of coherences in molecules and molecular aggregates. In order to evaluate the electronic coherences, which often decay on a 100 fs time scale, the early population times have to be included in the analysis. However, signals in this region
Hand fracture epidemiology and etiology in children - Time trends in Malmö, Sweden, during six decades
Background: The aim of this study was to describe hand fracture epidemiology/etiology in city children and describe time trend during six decades. Patients and methods: A single hospital serves the entire city population of 271,271 (year 2005). Through the hospital medical and radiological archives, we collected epidemiology and etiology data concerning pediatric (age < 16 years) hand fractures in
ESD Reviews : Climate feedbacks in the Earth system and prospects for their evaluation
Earth system models (ESMs) are key tools for providing climate projections under different scenarios of human-induced forcing. ESMs include a large number of additional processes and feedbacks such as biogeochemical cycles that traditional physical climate models do not consider. Yet, some processes such as cloud dynamics and ecosystem functional response still have fairly high uncertainties. In t
Preferences in regional public transport: a literature review
The purpose of this article is to analyse quality attributes of regional public transport and their influence on modal choice, demand, and customer satisfaction through a literature review. The review is based on a working definition of regional public transport with boundaries toward local as well as interregional public transport: Regional public transport (i) targets passengers travelling betwe
A new finger-preserving procedure as an alternative to amputation in recurrent severe Dupuytren contracture of the small finger
Background: Recurrent severe Dupuytren contracture of the small finger's proximal interphalangeal (PIP) joint is a difficult problem. Further surgery carries high risk of complications and poor outcome. Patients are often offered finger amputation. We have devised a novel surgical procedure consisting of middle phalanx monoblock resection and ligament reconstruction to create a new functioning int
Evidence of Augmented Intrarenal Angiotensinogen Associated With Glomerular Swelling in Gestational Hypertension and Preeclampsia : Clinical Implications
Background AGT (angiotensinogen) synthesis occurs in renal proximal tubular epithelial cells, independent from systemic AGT , as a component of the intrarenal renin-angiotensin system. We investigated urinary AGT , as a biomarker for renin-angiotensin system activation, and electrolyte concentrations, in relation to glomerular volume, as a proxy for glomerular endotheliosis in renal biopsy tissue
Capacity Development Guide
The Capacity Development Guide is a monograph produced for MSB the purpose of which is to provide necessary guidance and tools to those who are tasked with conceptualizing, designing and implementing capacity development initiatives, programs and projects. It is designed to enable professionals with adequate knowledge of capacity development to organize their thinking and plan processes in a more
Bioactive adrenomedullin, proenkephalin A and clinical outcomes in an acute heart failure setting
Objectives In an acute heart failure (AHF) setting, proenkephalin A 119-159 (penKid) has emerged as a promising prognostic marker for predicting worsening renal function (WRF), while bioactive adrenomedullin (bio-ADM) has been proposed as a potential marker for congestion. We examined the diagnostic value of bio-ADM in congestion and penKid in WRF and investigated the prognostic value of bio-ADM a
A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease
AIMS: Although the epidemiological association between Type 2 diabetes and congestive heart failure (CHF) as well as cardiovascular disease (CVD) is well established, associations between diabetes-related single-nucleotide polymorphisms (SNPs), CHF, and CVD have been surprisingly inconclusive. Our aim is to examine if 43 diabetes-related SNPs were associated with prevalent diastolic dysfunction as
Increased pulmonary blood volume variation in patients with heart failure compared to healthy controls; a non-invasive, quantitative measure of heart failure
Variation of the blood content of the pulmonary vascular bed during a heartbeat can be quantified by pulmonary blood volume variation (PBVV) using magnetic resonance imaging (MRI). The aim was to evaluate if PBVV differs in patients with heart failure compared to healthy controls and investigate the mechanisms behind the PBVV. Forty-six patients and 10 controls underwent MRI. PBVV was calculated f
Credo – en svensk-nordisk katolsk tidskrift i den katolska aktionen tjänst
För hundra år sedan började den katolska tidskriften Credo, föregångaren till dagens Signum, utkomma. Den var på många sätt typisk för sin tid och för de strömningar som då gjorde sig gällande i den katolska världen. I denna artikel analyseras Credo under pionjärtiden de första tolv åren och sätts in i sitt samtida katolska sammanhang.