Parkinson's disease (PD) patients display motor symptoms, e.g. tremor, rigidity and bradykinesia, largely due to a dramatic loss of dopaminergic neurons in the substantia nigra. Grafts of human embryonic dopamine neurons can survive in the striatum and reduce several of the motor symptoms. Several lines of evidence suggest that a crucial threshold of surviving dopaminergic neurons must be exceeded

The effects of varying extracellular concentrations of K+ and Ca2+ [K+]o and [Ca2+]o on force development and membrane potential were investigated in the guinea-pig mesotubarium. At [K+]o up to 40 mM, spontaneous action potentials were present, while higher [K+]o gave sustained contractures at a stable membrane potential (-24 to -12 mV for [K+]o from 60 to 120 mM). Tension decreased successively w

Parabolic planar compound refractive lenses (CRLs) made from glassy carbon by means of laser ablation are presented. They have radii of curvatures of 5 and 200 mu m and geometric apertures of 40 and 900 mu m, respectively. The numbers of biconcave elements in the CRLs were 4, 7, and 200. The planar lenses allow formation of a linear focus of length comparable with the depths of their profiles. Usa

A fully integrated 0.6 V VCO for the GPS L1 band is realized in a 90 nm RF-CMOS process. The purpose of the design is to demonstrate how suitable deep submicron CMOS transistors are for ultra low voltage, low power oscillator design. The VCO operates at 6.3 GHz and a divide-by-four circuit buffer provide the wanted 1575.42 MHz signal. Measured phase noise is for a 0.6 V supply voltage and bias cur

This paper presents application of sustainable tourism practices by leading tour operators in international ecotourism supply chains. Observations of actions implemented by the inbound and outbound operators creating the ecotourism experience are drawn from two case studies – one of trips to Peru and the other of trips to Nepal-Bhutan - both available on the Swedish market. The cases explore how s

High-spin states in Mo-88 were studied using the GAMMASPHERE germanium detector array in conjunction with the MICROBALL CsI(TI) charged-particle detector system. Three gamma-ray cascades with dynamic moments of inertia showing similar characteristics to superdeformed rotational bands observed in the neighbouring A = 80 region have been identified and assigned to the nucleus Mo-88. The quadrupole m

Popular Abstract in Swedish Ultraljud används inte bara som ett diagnostiskt hjälpmedel utan också som en behandlingsmetod. De terapeutiska områden som utforskas idag är destruktion av cancertumörer, behandling av diskbråck, ökning av antibiotikaeffekter, ökning av cellgiftseffekter och som i detta arbete, ökning av effekterna av propplösande läkemedel. Det görs även försök där ultraljud används fThe aim of this study was to further clarify the pro-fibrinolytic effects, and to explore the possible non-beneficial effects in ischemic organs, during exposure to pulsed ultrasound. This was accomplished by studies of the effects of different intensities of pulsed ultrasound exposure on the fibrinolytic properties of streptokinase and reteplase. Measurements were performed both following pre-exp

The model presented in this paper has been used for predicting the slab core temperature in several applications at The Danish Steel Works Ltd. The model has the advantages that it is simple and only contains a minimum of physical parameters, which makes it easy use and adapt to slab temperature measurements. The model has been verified using 11 data sets covering three different slab thicknesses

The aim of this study was to determine the influence of alpha-ketoglutarate (AKG) on volumetric bone density, geometrical and mechanical properties of femur and tibia in farm turkeys. All animals were kept under standard rearing conditions with constant access to water and appropriate feed, supplied in accordance with the stage of production cycle. Bone samples were collected 14 weeks after beginn

The purpose of this study was to evaluate amplification of topoisomerase IIalpha (TOP2A) and HER2 genes as predictors of response to chemotherapy in advanced breast cancer. Gene copy number of TOP2A and HER2 were analysed with chromogenic in situ hybridization (CISH) on paraffin-embedded tissue sections from the primary tumour of 85 patients treated with anthracycline containing chemotherapy. TOP2

The aim of this thesis is to examine the relationship between writing and alterity in three recent novels written by J. M. G. Le Clézio, Désert (1980), Onitsha (1991) and La quarantaine (1995), which deal with the encounter between the so-called primitive cultures and Western society. The first chapter contains a more general discussion on the discourse of alterity in literature and the French exo

We describe two patients with Grisel syndrome (atlantoaxial dislocation) after velopharyngoplasty. One required open fixation, while the other was treated with closed reduction and skull traction. Both patients recovered well after long-term follow-up. Early detection and appropiate treatment improve the prognosis.

It has been proposed that the developmentally supportive care of very-low-birthweight (VLBW) infants provided by the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) can improve the infants' opportunities for rest and sleep. The aim of the present study was to determine whether quiet sleep (QS) in VLBW infants is affected by NIDCAP care. Twenty-two infants with a gestation

A brief overview is given of a non-associated plasticity theory developed for soils based on the concept of a characteristic stress state of vanishing incremental dilation, and a calibration procedure using only test data from a standard triaxial test. The capability of the model is illustrated by calibration examples and predictions made for standard triaxial tests at different confining stress l

Abstract in Undeterminedhe atJthor dlscusses the relalionship betwccn peaplc and animals in a lime perspective of millcllnia. The starting point is the pre-Chri stian. $can­ dinavl:m. animal graves ofJogs and hoJ'SCs. the Saami hear-graves, as wdl as animal burials urmodern time. TIle occurrence ofanimal graves In pre­ Christian time and the wide mnge ofways to dispose of human and animal bodics c