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HvPIP1;6, a barley (Hordeum vulgare L.) plasma membrane water channel particularly expressed in growing compared with non-growing leaf tissues

The aim of the present study was to identify water channel(s) which are expressed specifically in the growth zone of grass leaves and may facilitate growth-associated water uptake into cells. Previously, a gene had been described (HvEmip) which encodes a membrane intrinsic protein (MIP) and which is particularly expressed in the base I cm of barley primary leaves. The functionality of the encoding

Co-ordination of spontaneous swallowing with respiratory airflow and diaphragmatic and abdominal muscle activity in healthy adult humans

Co-ordination of breathing and swallowing is essential for normal pharyngeal function and to protect the airway. To allow for safe passage of a bolus through the pharynx, respiration is interrupted (swallowing apnoea); however, the control of airflow and diaphragmatic activity during swallowing and swallowing apnoea are not fully understood. Here, we validated a new airflow discriminator for detec

Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival

Interleukin-6 (IL6) is a growth and survival factor in human prostate cancer (PCa) cells with aggressive phenotypes and has been implicated in the progression of hormone refractory PCas. In the present study, we characterized the IL6-triggered PI3K/Akt and MAPK/Erk signaling. We identified the A-type cyclin, cyclin A1 as an important downstream target of PI3K/Akt. Treatment of cells with PI3K inhi

High resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes

The rat Natural Killer cell gene Complex (NKC) encodes molecules that can regulate immunity. It is located within an interval on DA rat chromosome 4 (RNO4) that is linked to immune-mediated inflammatory joint diseases, including oil-induced arthritis (OIA). We aimed to test the hypothesis that NKC regulates arthritis, by performing advanced mapping of arthritis and additional phenotypes induced by

Cancer risk among patients hospitalized for Type 1 diabetes mellitus: a population-based cohort study in Sweden

P>Aims Type 1 diabetes mellitus (T1DM) is an autoimmune disease with potential mechanistic links to immune-related cancers. We aimed at examining the overall and specific cancer risks among hospitalized T1DM patients from the national registers in Sweden. Methods A T1DM research cohort was created by identifying T1DM patients from the Hospital Discharge Register and linking them with the Cancer Re

Sex differences in learning ability in a common songbird, the great tit-females are better observational learners than males

In mammals, including humans, the most consistent cognitive sex difference appears to be a male advantage in spatial ability. Usually, some sex-correlated selective advantage is inferred to explain this, for example, the need for males to navigate over large territories. In birds, sex differences in learning abilities are rare. Here, we show that females of a common European songbird, the great ti

Traditional Farming Landscapes for Sustainable Living in Scandinavia and Japan : Global Revival Through the Satoyama Initiative

Traditional, pre-industrial farming was adapted to the natural environment-topography, geology, hydrology, climate, and biota. Traditional land use systems are still to be traced in Scandinavia as an "infield/outland landscape", and in Japan as a "Satoyama landscape." There are obvious similarities and differences in land use-the main difference being that pasturing of cattle and sheep has been le

Serotonin uptake into cerebrovascular nerve fibers of rat, visualization by immunohistochemistry, disappearance following sympathectomy, and release during electrical stimulation

Immunohistochemistry as well as in vitro uptake and release of [3H]5-HT were performed on pial arteries of rat to investigate the nature of 5-HT containing nerve fibers. Immunoreactive fibers were constantly found only in the basilar, vertebral and superior cerebellar arteries, while in the other parts of the circle of Willis, 5-HT immunofluorescent fibers were absent. After systemic treatment wit

The Quantitative Relationship between Longitudinal and Radial Function in Left, Right and Total Heart Pumping in Humans.

The total heart volume variation (THVV) during systole has been proposed to be caused by radial function of the ventricles, but definitive data for both ventricles have not been presented. Furthermore, the right ventricle (RV) has been suggested to have a greater longitudinal pumping component than the left ventricle (LV). Therefore, we aimed to compare the stroke volume (SV) generated by radial f

Lifetime calculations for the 5s5p P-3(2) metastable level of Sr-88 I

We report on a large scale calculation concerning the 5s(2) S-1 and 5s5p P-1,P-3 levels in Sr-88 I, using multiconfiguration Dirac-Fock methods. Our focus is on the P-3(2) meta-stable level, which has been shown to be extremely useful in atom cooling and trapping experiments. The lifetime for this level from our work (1071 s) agrees very well with a previous theoretical value, but not with the ava

Probing doubly excited ionic states of N-2(+) via a triple excitation above the N 1s threshold in the N-2 molecule

Angle-resolved resonant Auger-electron spectroscopy has been carried out on the nitrogen molecule at selected photon energies around 419 eV, where a 1s core electron and two valence electrons are promoted into the lowest unoccupied molecular orbital 1pi(g). Significant enhancement of a specific band, which cannot be disentangled in direct photoionization, is observed at a binding energy of 37.6 eV

Impulse oscillometry may be of value in detecting early manifestations of COPD.

BACKGROUND: Spirometry is used to diagnose chronic obstructive pulmonary disease (COPD). The Impulse oscillometry system (IOS) allows determination of respiratory impedance indices, which might be of potential value in early COPD, although previous experience is limited. We examined pulmonary resistance and reactance measured by IOS in subjects with or without self-reported chronic bronchitis or

The effects of salt-curing and salting procedures on the microstructure of cod (Gadus morhua) muscle

The aim of this study was to investigate the effects of salting and different pre-salting procedures (injection and brining versus brining only) on the microstructure and water retention of heavy salted cod products. Salting resulted in shrinkage of fibre diameter and enlargement of inter-cellular space. Water was expelled from the muscle and a higher fraction became located in the extra-cellular

Temporal cultural landscape dynamics in a marginal upland area: agricultural expansions and contractions inferred from palynological evidence at Yttra Berg, southern Sweden

Agrarian history and local cultural landscape dynamics have been documented through pollen analysis of a peat core within the hamlet of Yttra Berg, which is situated in an upland area of southwest Sweden. The sequence covers the last 5,000 years, from Neolithic to modern time. Wood pasturing started at 2000 b.c., followed by grazing and small-scale cultivation with 500 year cycles from 650 b.c., a

Does Victim Age Differentiate Between Perpetrators of Sexual Child Abuse? A Study of Mental Health, Psychosocial Circumstances, and Crimes

To test the theory that sexual offenders who abuse very young children (0-5 years) have more severe mental health and psychosocial problems than those who victimize older children, authors compared psychiatric diagnoses, social circumstances, and crime-related data in all sexual offenders against minors referred to forensic psychiatric investigation in Sweden during a 5-year period. Thirty-one men

Isomeric Mirror States as Probes for Effective Charges in the Lower pf Shell

Following the fragmentation of a 550 MeV u(-1)primary beam of Ni-58, time-and energy-correlated gamma decays from isomeric states in neutron-deficient nuclei in the 1f(7/2) shell have been identified using the GSI fragment separator in combination with the RISING Ge-detector array. The results on isomers in the mirror pairs Ti-43(22)21-Sc-43(21)22 (I-pi = 3/2(+) and 19/2(-)), Cr-45(24)21-Sc-45(21)