The etiology of idiopathic scoliosis remains unknown, but growth is a risk factor for progression. Growth pattern differs in children with and without scoliosis. Cartilage oligomeric matrix protein (COMP) may be associated with scoliosis and growth. We, therefore, studied COMP in children with and without idiopathic scoliosis. We included 105 children, with mean age 14.4 years (range 10-16), under

1. Self-medication is an ability to consume or otherwise contact biologically active organic compounds specifically for the purpose of helping to clear a (parasitic) infection or reduce its symptoms. Consumption of these compounds may either take place before the infection is contracted (prophylactic consumption) or after the infection is contracted (therapeutic consumption). 2. An important insig

Detection of C2H2 via UV photo-fragmentation, followed by monitoring the C(2)d(3)Pi(g)-a(3)Pi(u) fluorescence, is explored at atmospheric pressure and at temperatures of 295 K, 600 K, and 800 K, for excitation wavelengths 210 to 240 am using a broadband laser source (similar to 3 cm(-1) fwhm). At the lower temperature, C-2 emissions correlate closely with C2H2 (A) over tilde

Aim: To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias. Methods: A secondary analysis of a randomized controlled study in 70 patients with Parkinson's disease dementia (PDD) or dementia with Lewy bodies (DLB) over 24 weeks using caregiver-rated QOL-Alzheimer's disease (AD) in domains according to the WHO's classification of health. Resu

Purpose of review: We review recent evidence regarding risk factors for childhood posttraumatic stress disorder (PTSD) and treatment outcome studies from 2010 to 2012 including dissemination studies, early intervention studies and studies involving preschool children.Recent findings: Recent large-scale epidemiological surveys confirm that PTSD occurs in a minority of children and young people expo

In the past, ABO incompatibility was considered an absolute contraindication to heart transplantation (HT) in adults. Advances in ABO-incompatible HT in pediatric patients and ABO-incompatible abdominal transplantation in adult patients have led to clinical exploration of intentional ABO-incompatible HT in adults. However, it is not well known how outcomes in ABO-incompatible adult heart transplan

The aim of this article is to reveal how care managers handle the process when older people consider relocation to a residential home in a Swedish context. The article is based on vignette-based interviews with seven care managers. The main findings in the article are that the care managers assist older people in their decisions by turning ageing in place and relocation respectively into seemingly

The molecular background of the Ca2+-sensitizing effect of levosimendan relates to its specific interaction with the Ca2+-sensor troponin C molecule in the cardiac myofilaments. Over the years, significant preclinical and clinical evidence has accumulated and revealed a variety of beneficial pleiotropic effects of levosimendan and of its long-lived metabolite, OR-1896. First of all, activation of

Apolipoprotein M (ApoM) protects against atherosclerosis; however, it is unknown whether it also protects against recurrent venous thromboembolism (VTE).

It has been shown that organized screening decreases prostate cancer (PC) mortality, but the effect of opportunistic screening is largely unknown.

A structural affinity between republican freedom as non-domination and human rights claims accounts for the relevance of republicanism for cosmopolitan concerns. Central features of republican freedom is its institution dependence and the modal aspect it adds to being free. Its chief concern is not constraint, but the way in which an agent is constrained or not. To the extent I am vulnerable to so

In this work we have used simple microfabrication techniques and chemical de-alloying of co-sputtered AgAu alloys to create nanoporous gold (np-Au) electrodes. The physical properties of the np-Au electrodes were investigated using scanning electron microscopy with energy dispersive X-ray analysis, X-ray photo-electron spectroscopy and profilometer. The electrochemical performance of the np-Au ele

P>Lilja M. School attainment of children who had a single umbilical artery at birth. Paediatric and Perinatal Epidemiology 2010; 24: 166-170. To the best of our knowledge, this is the first registry study of school achievements among children born with a single umbilical artery (SUA). A total of 1600 infants born with SUA during 1983-86 were studied. We linked the Swedish Medical Birth Registry wi

We discovered a symbiotic lactic acid bacterial (LAB) microbiota in the honey stomach of the honeybee Apis mellifera. The microbiota was composed of several phylotypes of Bifidobacterium and Lactobacillus. 16S ribosomal ribonucleic acid (rRNA) gene analyses and phenotypic and genetic characteristics revealed that the Lactobacillus phylotypes isolated represent seven novel species. One is grouped w

In this paper, we present geochronological, geochemical and palaeomagnetic results from the Hlagothi Complex and a NW-trending dolerite dyke swarm on the southeastern region of the Kaapvaal Craton in northern KwaZulu-Natal, South Africa. The Hlagothi Complex consists of layered sills of meta-peridotite, pyroxenite and gabbro intruding into the Pongola Supergroup. U-Pb baddeleyite ages on the Hlago

HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) kills tumor cells broadly suggesting that conserved survival pathways are perturbed. We now identify nucleotide-binding proteins as HAMLET binding partners, accounting for about 35% of all HAMLET targets in a protein microarray comprising 8000 human proteins. Target kinases were present in all branches of the Kinome tree, including 26 tyr

The growth of Fe nanoclusters on the Ge(001) and MoO2/Mo(110) surfaces has been studied using low-temperature scanning tunneling microscopy (STM) and X-ray magnetic circular dichroism (XMCD). STM results indicate that at low coverage Fe atoms self-assemble on both surfaces into well-separated nanoclusters, which nucleate at equivalent surface sites. Their size, shape, and the observed spatial sepa

Background: Cyclosporine (CsA) or infliximab (IFX) are used as rescue therapies in steroid-refractory, severe attacks of ulcerative colitis (UC). There are no data comparing the efficacy of these two alternatives. Methods: Outcome of rescue therapy was retrospectively studied in two cohorts of patients hospitalized due to steroid-refractory moderate to severe UC: 1) a Swedish-Danish cohort (n 49)