Objective Women with SLE face an increased risk of adverse pregnancy outcomes compared with healthy women, but the underlying immunological mechanisms are unknown. Given the recognised association of neutrophil activation with SLE pathogenesis, we examined whether there is increased neutrophil activation and inflammation in blood and placenta in SLE relative to healthy pregnancy. Methods At delive

BACKGROUND AND PURPOSE: To date, large studies comparing mortality and functional outcome of intracerebral hemorrhage (ICH) during oral anticoagulant (OAC), antiplatelet, and nonantithrombotic use are few and show discrepant results. METHODS: We used data on 13 291 patients with ICH registered in Riksstroke between 2012 and 2016 to compare 90-day mortality and functional outcome following OAC-rela

Intralocus sexual conflict arises when the expression of shared alleles at a single locus generates opposite fitness effects in each sex (i.e. sexually antagonistic alleles), preventing each sex from reaching its sex-specific optimum. Despite its importance to reproductive success, the relative contribution of intralocus sexual conflict to male pre- and post-copulatory success is not well-understo

This study focus on digital tools and software programmes used in SI. It combines a case study for the SI programme at Lund University with an international overview. The digital tools are divided in categories based on where they are used in SI. Digital tools for SI leaders are usually tools for communication with participants between sessions (Facebook, Messenger, WhatsApp, etc.); sharing good p

Modern agricultural production typically requires large quantities of chemical pesticides, a potential source of both environmental and human harm. Previous social science research has suggested that environmental problems such as those associated with pesticide use may begin to decline at higher levels of economic development. Using fixed effects models, we examine whether this possible relations

We develop the theory of modulated operators in general principal ideals of compact operators. For Laplacian modulated operators we establish Connes' trace formula in its local Euclidean model and a global version thereof. It expresses Dixmier traces in terms of the vector-valued Wodzicki residue. We demonstrate the applicability of our main results in the context of log-classical pseudo-different

Country case study for an international report on the COVID-19 management in 16 countries with a focus on health, economic, and political dimensions and outcomes.

Venous thromboembolism constitutes a major medical problem afflicting millions of individuals worldwide each year. Its pathogenesis is multifactorial, involving both environmental and genetic risk factors. The most common genetic risk factor known to date is a mutation in the factor V (FV) gene (R506Q or FV Leiden), which impairs the normal regulation of FV by activated protein C (APC). APC is an

Background: Previous studies have shown that copy number variation (CNV) in the alpha (α)-amylase gene (AMY1A) is associated with body mass index, insulin resistance, and blood glucose levels, factors also shown to increase the risk of Alzheimer’s dementia (AD). We have previously demonstrated the presence of α-amylase in healthy neuronal dendritic spines and a reduction of the same in AD patients

This past Friday, the architect of the Iranian nuclear program, Mohsen Fakhrizadeh, was assassinated in a well-organized raid 70 km outside the city of Tehran. A commander of the Islamic Revolutionary Guard Corps (IRGC), Fakhrizadeh headed the important Organization of Defensive Innovation and Research of the Ministry of Defense, which conducted nuclear weapons research. His killing reflects a maj

The largest part of this collection is linguistic material, including video-recorded conversations and narratives, elicited words and sentences, a lexicon, and recordings of people interacting with different stimulus materials like picture books or short video clips. A large part of the audiovisual and elicited material is translated into English and Papuan Malay and analysed at morpheme level. In

This is a small collection of linguistic materials in Geser-Gorom (ISO639-3:ges), a language spoken in eastern Seram and on the islands off the eastern Seram coast, Seram Bagian Timur regency, Maluku province, Indonesia (-3.717798, 130.767276).All recordings were made in Mas village, Karas islands, Fakfak regency, West Papua province, Indonesia, which has several Geser-Gorom speakers and at the ti

Purpose: For exercise testing of COPD patients, a standard endurance test (ET) with constant workload is recommended. The test suffers from large inter-individual variability and need for large sample sizes in order to evaluate treatment effects. Methods: A new protocol for ET in COPD was designed. In contrast to the standard ET, the new ET involved an increasing workload in order to reduce the st

Neuroscience of the self has focused on high-level mechanisms related to language, memory or imagery of the self. However, recent evidence suggests that low-level mechanisms such as multisensory and sensorimotor integration may play a fundamental role in self-related processing. Here we used virtual reality technology and visuo-tactile conflict to study such low-level mechanisms and manipulate whe