Sökresultat

Filtyp

Din sökning på "*" gav 531351 sökträffar

RT-PCR analysis of the MOZ-CBP and CBP-MOZ chimeric transcripts in acute myeloid leukemias with t(8;16)(p11;p13)

The translocation t(8;16)(p11;p13) is associated with a subtype of acute monocytic leukemia (AML M5) characterized morphologically by erythrophagocytosis and clinically by a poor prognosis. The t(8;16) fuses the MOZ gene from 8p11 with the CBP (also named CREBBP) gene from 16p13. Previously published studies of MOZ and CBP rearrangements in t(8;16)-positive AML have used fluorescence in situ hybri

Estimates of the prevalence and number of Fibromyalgia syndrome patients and their alpha-1 antitrypsin phenotypic distribution in ten countries

Objectives: During the last few years, clinical, epidemiological, and pathological evidence has suggested that inherited alpha-1 antitrypsin [AAT] deficiency might play a role in the development of the fibromyalgia syndrome [FMS], probably because of the loss of AAT anti-inflammatory efficacy. The objective of this study was to estimate the prevalence and number of FMS patients, and their AAT phen

Vibration-induced shift of the subjective visual horizontal - A sign of unilateral vestibular deficit

Background: Vibration to the head or neck excites vestibular and neck muscle spindle afferents. Can such vibrations improve the sensitivity of the subjective visual horizontal (SVH) test to chronic unilateral deficit of the vestibular system? Design: Controlled experimental study. Setting: Tertiary referral center. Patients and Controls: Thirteen healthy subjects and 23 patients with chronic unila

Amine oxidase amperometric biosensor coupled to liquid chromatography for biogenic amines determination

A selective and sensitive method is presented for biogenic amines (BA) determination. The novelty consists in coupling a highly selective electrochemical biosensor to a weak acid cation-exchange column for online detection of amines. A bienzyme design, based on a recently isolated amine oxidase from grass pea and commercial horseradish peroxidase, was used for the biosensor construction. The enzym

Thermal analysis of plate condensers in presence of flow maldistribution

Flow maldistribution in plate heat exchangers causes deterioration of both thermal and hydraulic performance. The situation becomes more complicated for two-phase flows during condensation where uneven distribution of the liquid to the channels reduces heat transfer due to high liquid flooding. The present study evaluates the thermal performance of falling film plate condensers with flow maldistri

Circulating oxidized low-density lipoprotein is increased in hypertension

Oxidized low-density lipoprotein (OxLDL) and autoantibodies to OxLDL (aOxLDL) are implicated in the development of atherosclerosis. The objective of this study was to determine the importance of these factors in hypertension, a major risk factor for atherosclerosis. Samples were obtained from I I I men with established hypertension (diastolic pressure > 95 mmHg) from the Swedish component of an on

Development of an artificial neural network model for the steam process of a coal biomass cofired combined heat and power (CHP) plant in Sweden

The development of a model for any energy system is required for proper design, operation or its monitoring. Models based on accurate mathematical expressions for physical processes are mostly useful to understand the actual operation of the plant. However, for large systems like combined heat and power (CHP) plants, such models are usually complex in nature. The estimation of output parameters us

Can quality of life be improved by pelvic floor muscle training in women with urinary incontinence after stroke? A randomized,controlled and blinded study

The purpose of this study was to evaluate the effect of pelvic floor muscle training in women with urinary incontinence after ischmic stroke measured by quality of life parameters. Three hundred thirty nine medical records of stroke patients were searched. Twenty-six subjects were randomized to a treatment group or a control group in a single-blinded,randomized study design. The intervention inclu

Chronicity of pristane-induced arthritis in rats is controlled by genes on chromosome 14

To, address; he possibility, that genes specifically control the chronic phase of arthritis we have isolated a congenic fragment from the resistant E3; rat cm the, susceptible DA rat background. The isolated fragment covers the Pia6 quantitative trait locus on chromosome 14, which previously has been identified to be linked to chronic pristane induced arthritis (PIA) in gene segregation experiment

Mixing in circular and non-circular jets in crossflow

Coherent structures and mixing in the flow field of a jet in crossflow have been studied using computational (large eddy simulation) and experimental (particle image velocimetry and laser-induced fluorescence) techniques. The mean scalar fields and turbulence statistics as determined by both are compared for circular, elliptic, and square nozzles. For the latter configurations, effects of orientat

Photoactivation and Photoinhibition Are Competing in a Mutant of Chlamydomonas reinhardtii Lacking the 23-kDa Extrinsic Subunit of Photosystem II

The process of photoactivation has been studied in dark grown cells of Chlamydomonas reinhardtii. A mutant, FUD 39, lacking the Cl-concentrating 23-kDa psbP protein of photosystem II was found to have a decreased capability to perform photoactivation. The yield of the process never reached wild type level, and contrary to the wild type, it was highly dependent on the intensity of the activating li

The DAL10 gene from Norway spruce (Picea abies) belongs to a potentially gymnosperm-specific subclass of MADS-box genes and is specifically active in seed cones and pollen cones.

Transcription factors encoded by different members of the MADS-box gene family have evolved central roles in the regulation of reproductive organ development in the flowering plants, the angiosperms. Development of the stamens and carpels, the pollen- and seed-bearing organs, involves the B- and C-organ-identity MADS-box genes. B- and C-type gene orthologs with activities specifically in developin

Effects of a goal-oriented rehabilitation program in mild cognitive impairment: A pilot study

Background: Memory disturbance, deficient concentration, and fatigue are symptoms seen in amnestic mild cognitive impairment (MCI) as well as in mild traumatic brain injury (TBI). The aim of this study was to assess if an established rehabilitation program commonly used in TBI can aid MCI patients to develop compensatory memory strategies that can improve their cognition, occupational performance,

Palynology of Permian shale, clay and sandstone clasts from the Basen till in northern VestfJella, Dronning Maud Land

The palynological content of randomly collected sedimentary rock clasts from the till on the south-east slope of the Basen nunatak in northern Vestfiella in western Dronning Maud Land indicate that these sedimentary rocks were derived from strata of Middle Permian age. The palynological content and preservation is similar to palynofloras described from the sedimentary rocks that crop out at the Fo

The influence of collembolans and earthworms on AM fungal mycelium

Arbuscular mycorrhizal (AM) mycelia are dependent on contact with plant roots for spore formation. In this study, earthworms and collembolans were regarded as potential dispersal vectors of AM fungal spores and hyphae, and we determined how they influenced the extension of AM fungi from host plant roots. Plantago lanceolata seedlings were grown in a mesh bag with an AM inoculurn of dried soil and

Functional activity of insulinoma cells (INS-1E) and pancreatic islets cultured in agarose cryogel sponges

Here, we describe the preparation, structure, and properties of cryogel sponges, which represent a new type of macroporous biomaterial for tissue engineering. Cryogels were produced through freeze-thawing techniques, either from agarose alone or from agarose with grafted gelatin. The aim of this study was to evaluate agarose cryogel sponges as scaffolds for Culturing both isolated pancreatic islet