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An assessment of disease flare in patients with systemic lupus erythematosus: a comparison of BILAG 2004 and the flare version of SELENA

Aims To compare the British Isles Lupus Assessment Group (BILAG) 2004, the Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) flare index (SFI) and physician's global assessment (PGA) in assessing flares of disease activity in patients with systemic lupus erythematosus (SLE). Methods Sixteen patients with active SLE were assessed by a panel of 16 rheumatologists. The order in

Controlling particle morphology and size in the synthesis of mesoporous SBA-15 materials

Plate-like particles of SBA-15 form from smaller units (primary particles) that aggregate in an oriented manner. In this report we influence this aggregation by adding salt to the ongoing synthesis, generating well-ordered hexagonal p6m structure (SBA-15), with varying particle diameters. The additions, with either NaCl or NaI, were made at a time corresponding to the onset of oriented aggregation

Sealed Glass Tube Combustion of mu g-Sized Aerosol Samples

It is important to evaluate each step in radiocarbon analysis to ensure that the whole process is as efficient and accurate as possible. Aerosol filter samples contain a myriad of carbonaceous compounds with varying resistance to oxidation. Complete combustion of the sample is thus of great importance to ensure that the graphitized sample is representative of the original filter sample. We have ev

Lipoprotein-associated phospholipase A2 (Lp-PLA2) Impact and role as cardiovascular risk marker

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is today considered a novel specific vascular inflammatory biomarker. The general aim of this thesis was to study the role and impact of Lp-PLA2 as cardiovascular (CV) risk marker in an epidemiologic perspective. Specific aims were to explore the cross-sectional association of Lp-PLA2 with traditional CV risk factors, to asses the genetic influence

No title

This doctoral thesis is a psychoanalytic interpretation of the novels of the Peruvian author Mario Vargas Llosa, and it explores these novels from three different perspectives, here called readings. The first perspective focuses on the literary techniques and the importance these may have for the interpretation of the content of the novels. This first reading includes a summary of the reception of

A Sequential Control Language for Industrial Automation

Current market trends for industrial automation are the need for customizable production, shorter time to market, and powerful global competitive pressure. Based on these trends two challenges have been identified: 1) flexible production systems and 2) integration and utilization of devices and software. Applications from both process automation, manufacturing, and robotics have been considered.

Experimental determination of the respiratory tract deposition of diesel combustion particles in patients with chronic obstructive pulmonary disease

Background: Air pollution, mainly from combustion, is one of the leading global health risk factors. A susceptible group is the more than 200 million people worldwide suffering from chronic obstructive pulmonary disease (COPD). There are few data on lung deposition of airborne particles in patients with COPD and none for combustion particles. Objectives: To determine respiratory tract deposition o

Determination of heat transfer coefficient during high pressure frying of potatoes

Besides traditional atmospheric frying, high pressure (super-atmospheric) frying might be an alternative approach to the frying of food products. In this study, convective heat transfer coefficient during atmospheric and high pressure frying was compared. For this purpose, a pressure cooker was modified to allow the immersion of a sample into frying oil under pressure and temperature measurement o

A 60 GHz receiver front-end with PLL based phase controlled LO generation for phased-arrays

This paper presents a front-end architecture for fully integrated 60 GHz phased array receivers. It employs LO-path beamforming using a phase controlled phase-locked loop (PC-PLL). To demonstrate the architecture a circuit is implemented featuring a two stage low noise amplifier, two cascaded active mixers, and a PC-PLL. The receiver downconverts the 60 GHz signal in two steps, using LO signals fr

Origin of the Bathochromic Shift of Astaxanthin in Lobster Protein: 2D Electronic Spectroscopy Investigation of beta-Crustacyanin

We report on ultrafast spectroscopy study of beta-crustacyanin, the carotenoprotein responsible for the coloration of the lobster shell. beta-Crustacyanin is formed by two closely positioned astaxanthin molecules encapsulated in protein. The 2D electronic spectroscopy together with two-color pump-probe was applied to investigate the electronic structure, the excited-state dynamics, and the influen

Hereditary colorectal cancer diagnostics: morphological features of familial colorectal cancer type X versus Lynch syndrome

Background The hereditary non-polyposis colorectal cancer (HNPCC) subset of tumours can broadly be divided into tumours caused by an underlying mismatch-repair gene mutation, referred to as Lynch syndrome, and those that develop in families with similar patterns of heredity but without disease-predisposing germline mismatch repair mutations, referred to as familial colorectal cancer type X (FCCTX)