Abstrakt. Ett etablerat MP2RAGE-protokoll för semikvantitativ strukturell hjärn-MRI överfördes frånen 7T MR-skanner till en annan leverantör med jämförbar hårdvara, men motsatt polaritet. På det härsystemet, kan skanningstiden reduceras från 11 till 8 minuter genom elliptisk k-space-sampling. Tre konfigurationerav radiofrekvens (RF) överföring jämfördes (enkelkanal med kvadraturen slits, två och åAbstract. An established MP2RAGE protocol for semi-quantitative structural brain MRI was transferred from one 7T MR scanner to that of another vendor featuring comparable hardware, but opposite polarity. On this system, the scan time could be reduced from 11 to 8 minutes by elliptical k-space sampling. Three configurations of radio-frequency (RF) transmission were compared (single channel with qua

The objective is to study the effect of high voltage pulses on living cells to find the most effective combination of physical parameters to be used in tumour therapy. Four parameters that affect the cell survival are the pulse shape, electric field strength, pulse length and the number of pulses and their cell killing effect were investigated in this work. High voltage square wave or exponentiall

Objective. To report the first clinical evaluation of a new balloon endometrial, thermal destruction system Cavaterm®, for outpatient treatment of menorrhagia. Design. To elucidate possible technical problems during treatment, to evaluate how the patients tolerated the treatment and to judge which patients were suitable for this form of treatment. Main outcome measures. Measurements of bleeding vo

Thermotherapy of the uterus has emerged as an alternative to hysterectomy in the treatment of menorrhagia, from whence it follows that the thermal properties of uterine tissue have become of importance. This study presents measurements of the thermal conductivity and the water content of uterine tissue in vitro. A steady-state thermal conductivity apparatus, based on the comparison of test samples

Objective To estimate, using numerical calculations, the depth of tissue damage in the uterus following balloon thermal endometrial destruction. Design A parameter, therapeutic depth, was defined. This was the maximum depth into the uterine myometrium, from the uterine cavity, at which a predefined temperature was reached after a certain time and with a constant intracavitary temperature. Setting

This study tested the effect of repeated intratumoural injection with recombinant interleukin-2 (rIL-2) and tumour-infiltrating lymphocytes (TILs) on inhibition of growth of breast cancer and on induction of apoptosis of tumour cells. The tumour cell line LDLX43 was used to induce breast cancer in Wistar rats. Group I (10 rats) was the control. Group II (12 rats) received repeated intratumoural in

Background. Treatment of menorrhagia by heat-destruction of the endometrium, intended to be an alternative to hysterectomy, was investigated in an experimental study. Method. A specially designed catheter (Cavaterm™) with a silicone balloon containing a self-regulating heating element is inserted into the uterus, rilled with glycine to a pressure of around 180 mmHg and heated to about 75°C. We inv

Biological effects of electromagnetic fields (EMF) on the blood‐brain barrier (BBB) can be studied in sensitive and specific models. In a previous investigation of the permeability of the blood‐brain barrier after exposure to the various EMF‐components of proton magnetic resonance imaging (MRI), we found that the exposure to MRI induced leakage of Evans Blue labeled proteins normally not passing t

Electrical impedance tomography (EIT) has to be improved in order to become an accepted diagnostic technique in clinical use. The aim of this study is to improve the hardware of this technique and preferably upgrade the current injecting device. Instead of using a constant current generator the idea is to implement a voltage source and measure current accurately, in order to improve the resolution

Three-dimensional electromagnetic calculations for loaded transverse electromagnetic (TEM) transmission cells are presented. Based on those calculations a prediction of the perturbation of the standard uniform field in the TEM-cell, due to the scattering by inhomogeneous structures placed inside the cell cavity, is given. The influence of the dimensions of a lossy structure and its position in the

The biological effects of electromagnetic fields (EMFs) on the blood-brain barrier (BBB) can be studied in sensitive and specific models. In a previous investigation of the permeability of the BBB after exposure to the various EMF -components of proton magnetic resonance imaging (MRI), we found that exposure to MRI induced leakage of Evans-blue-labelled proteins which do not normally pass the BBB

It has been suggested that electromagnetic fields (EMFs) act as a promoter late in the carcinogenesis process. To date, however, noconvincing laboratory evidence has been obtained indicating that EMFs cause tumour promotion at non-thermal exposure levels. The effects of EMF exposure in a rat brain glioma model were investigated. The exposure consisted of 915 MHz microwaves, both as continuous wave

Studies of native syntactic processing often target phrase structure violations that do not occur in natural production. In contrast, this study examines how variation in basic word order is processed, looking specifically at structures traditionally labelled as violations but that do occur naturally. We examined Swedish verb-second (V2) and verb-third (V3) word order-processing in adult native Sw

Streptococcus pneumoniae (the pneumococcus) colonizes the human nasopharynx by forming multicellular biofilms. Due to the high level of asymptomatic carriage, transition to infections, such as otitis media, pneumonia, sepsis, and meningitis, occurs often enough that the pneumococcus remains a major cause of disease and death globally. Virus infection and virus-induced responses, such as increased

Context. Open clusters are recognised as excellent tracers of Galactic thin-disc properties. At variance with intermediate-age and old open clusters, for which a significant number of studies is now available, clusters younger than ≲ 150 Myr have been mostly overlooked in terms of their chemical composition until recently (with few exceptions). On the other hand, previous investigations seem to in

The formation of biomolecular condensates inside cells often involve intrinsically disordered proteins (IDPs), and several of these IDPs are also capable of forming dropletlike dense assemblies on their own, through liquid-liquid phase separation. When modeling thermodynamic phase changes, it is well known that finite-size scaling analysis can be a valuable tool. However, to our knowledge, this ap

Fission-fragment mass and total-kinetic-energy (TKE) distributions following fission of even-even nuclides in the region 74 ≤ Z≤ 126 and 92 ≤ N≤ 230 , comprising 896 nuclides have been calculated using the Brownian shape-motion method. The emphasis is the region of superheavy nuclei. To show compatibility with earlier results the calculations are extended to include earlier studied regions. An isl

Background: The role of insulin resistance as a mediator in the association of body mass index (BMI) with site-specific cancer risk has, to our knowledge, never been systematically quantified. Methods: Altogether 510 471 individuals from six European cohorts, with a mean age of 43.1 years, were included. We used the triglyceride glucose product (TyG index) as a surrogate measure for insulin resist