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Effects on Serum Protein Levels From One Bout of High Intensity Interval Training in Individuals With Axial Spondyloarthritis and Controls

BACKGROUND: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the axial skeleton causing pain, inflammation, and stiffness. Individuals with axSpA are at greater risk of developing cardiovascular disease, which can be counteracted by physical activity. High-intensity interval training (HIIT) has been shown to improve cardiovascular health, but the effect on dise

"In my soft girl era" - En kritisk feministisk studie om femininitet inom soft-girl trenden

This thesis explores how femininity is constructed within the soft girl trend, using Butler’s theoretical framework of the heterosexual matrix and theory of (gender) performativity. By combining digital ethnography, multimodal critical discourse analysis, and a critical feminist perspective, this study aims to contribute to a deeper understanding of how femininity is expressed, reproduced and aest

Design of Glycosyltransferase Inhibitors : Targeting the Biosynthesis of Glycosaminoglycans by Phosphonate-Xyloside

β-1,4-Galactosyltransferase 7 (β4GalT7) is a key enzyme in the biosynthesis of glycosaminoglycans (GAG) that transfers the first galactose unit to xylose in the linker region. Searching for new inhibitors of the GAG biosynthesis, we used saturation transfer difference (STD) nuclear magnetic resonance (NMR) spectroscopy to evaluate the binding interactions between β4GalT7 and several pentosides in

Blood-based biomarkers for detecting Alzheimer's disease pathology in cognitively impaired individuals within specialized care settings : A systematic review and meta-analysis

BACKGROUND: This systematic review and meta-analysis aimed to assess the diagnostic test accuracy of blood-based biomarkers (BBMs) for detecting Alzheimer's disease (AD) pathology in cognitively impaired individuals in specialized care settings. The overarching goal is to inform the development of a clinical practice guideline, led by the Alzheimer's Association, for use in clinical practice. METH

Gender Differences in Self-Promotion and Career Advice

We study the role of self-promotion and career advice in sustaining gender differences in labor market outcomes. We conduct an online experiment in which “advisers” advise “workers” to choose between a more ambitious and a less ambitious task based on the worker’s subjective self-assessment. We find that women have lower self-assessments and receive less ambitious career advice as a result. We als

Grannelagsrätt : Seminarium 28 november 2024

Vi har sedan 2009 ordnat seminarier som ger klara och handfasta besked på centrala fastighetsrättsliga ämnen. Denna gång är ämnet Grannelagsrätt. Rättsförhållanden mellan grannar i 3 kap jordabalken utgör grunden för grannelagsrätten, men grannelagsrättsliga frågor regleras även i miljöbalken och plan- och bygglagen.

Buoyancy effects on combustion products from high-pressure hydrogen jet flames

Due to the lower radiative fraction and typically higher storage pressures, gas temperatures can often result in longer safety distances compared to radiative heat transfer for hydrogen jet flames. The high temperatures, however, also lead to a low density causing the flow to rise at a certain distance from the release. Unfortunately, a model to determine this distance, similar to what is availabl

Characterisation of fire smoke emissions from fire retardant wood

Fire retardants are extensively used to reduce the flammability (combustibility) of wood–based construction materials in an effort to improve fire safety of buildings. However, little is known of the composition and potential risks to human health of smoke emissions produced from combustion of fire retardant treated wood. To help understand the risk to human health, fire smoke emissions produced f

Design of stiff elasto-plastic structures

This study investigates “stiffness” optimization of path-dependent elasto-plastic structures by comparing the traditional secant stiffness formulation with a novel tangent stiffness formulation. Design updates are generated using the gradient-based Method of Moving Asymptotes (MMA), and the material behavior is modeled and limited to small-strain elasto-plasticity and isotropic hardening. Numerica

Federated Learning for Obstacle Detection to Assist the Visually-Impaired Using Augmented Reality

Vision impairment increases risks such as social isolation, mobility challenges, and falls. Wearable Augmented Reality (AR) devices with Artificial Intelligence (AI) can enhance sensory perception by enabling real-time recognition of obstacles, assisting visually impaired individuals during street navigation, aiming to reduce the risk of falls. In this paper, we propose a Federated Learning (FL) f

Discrepancies in testing, classification and performance of bio-based insulation materials

The fire behaviour of bio-based insulation materials is studied by comparing results from Cone Calorimeter and small-scale furnace tests. Clear differences in fire behaviour were observed between wood fibre and hemp fibre insulation. The analysis reveals that smouldering plays a critical role, particularly in furnace tests. Limitations of current fire resistance tests are highlighted, particularly

Quantifying the Heat Release of Wood Fiber Insulation using Small-Scale Calorimetry

Bio-based insulation materials, such as wood fiber, offer sustainable alternatives to conventional insulation but pose challenges due to their combustibility, particularly their smouldering behavior. This study investigates the heat release characteristics of wood fiber insulation using a combination of Simultaneous Thermal Analysis (STA) and Microscale Combustion Calorimetry (MCC) to assess both

Interplay between astrocyte reactivity and APOE ε4 status is associated with accelerated pTau-related tau pathology in Alzheimer’s disease

Background: Various plasma phosphorylated tau species have been shown to be associated with amyloid-β (Aβ) PET and Tau PET in Alzheimer’s disease (AD), but whether APOE ε4 affects the interaction between glial fibrillary acidic protein (GFAP) and phosphorylated tau (pTau), and whether a three-way interaction exists among APOE ε4, GFAP, and pTau that influences AD progression remain unclear. Method

Systemic and local decorin levels mirror the clinical course of pancreatic cancer

Despite significant progress in oncology research, pancreatic cancer remains inherently difficult to treat, and the mechanisms underlying therapeutic resistance remain unresolved. Decorin (DCN), a member of the family of small leucine-rich proteoglycans, has emerged as a versatile actor in various malignant diseases. The aim of this study was to further explore the potential clinical significance

Optimization-Based Path-Velocity Control for Time-Optimal Path Tracking under Uncertainties

This paper addresses the path-tracking problem of time-optimal trajectories under model uncertainties, by proposing a real-time predictive scaling algorithm. The algorithm is formulated as a convex optimization problem, designed to balance the trade-off between improving feasibility and time optimality of a trajectory. The predicted trajectory is scaled based on the presence of path segments that

Perception, control, and hardware for in-hand slip-aware object manipulation with parallel grippers

Dexterous in-hand manipulation offers significant potential to enhance robotic manipulator capabilities. This paper presents a sensori-motor architecture for in-hand slip-aware control, being embodied in a sensorized gripper. The gripper in our architecture features rapid closed-loop, low-level force control and is equipped with sensors capable of independently measuring contact forces and sliding

Lyssnande, samarbete & drivkraft: En text och studie i lyssnande, samverkan och målmedvetenhet mellan musiker

Arbetets syfte är att genom intervjuer ta reda på hur viktigt samverkan och företagsamhet är för alla musiker och kompositörer. Hur hör detta ihop med lyssnande och samverkan i repetitions- eller konsertsalen? Vad tycker dirigenten är viktigt för att driva en orkesterrepetition framåt? Vilken väg ska en kompositör gå för att komma i kontakt med konserthusen? Med intervjuer av kollegor och professoThe aim of the work is to find out through interviews how important collaboration and entrepreneurship are for all musicians and composers. How does this relate to listening and collaboration in the rehearsal or concert hall? What does the conductor think is important to drive an orchestral rehearsal forward? What route should a composer take to get in touch with concert halls? Through interviews

Evaluation of [18F]PSMA-1007 uptake variability in patients with prostate cancer

Background: The biodistribution of PSMA-ligands is of interest in radionuclide therapy planning. We investigated the variability of [18F]PSMA-1007 uptake in organs at risk and in relation to tumour burden in prostate cancer patients. Methods: A total of 1086 patients who underwent PSMA PET-CT for staging or recurrence of prostate cancer were included. Total lesion volume (TLV) and total lesion upt