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Close international collaboration between pediatric oncologists has led to marked improvements in the cure of patients, seen as a long-term overall survival rate of about 80%. Despite this progress, neuroblastoma remains a challenging disease for both clinicians and researchers. Major clinical problems include lack of acceptable cure rates in high-risk neuroblastoma and potential overtreatment of

The BIA method, based on assessment of patients in activities, was developed to enable reliable assessment of clients' occupational functioning. The method evaluates the patient's ego functions and capacity for activity and participation. The aims of this study were to examine inter-rater reliability for the BIA method and to compare the experiences of staff working with the BIA with those of staf

Approximately 1 in 10 couples is infertile No definite cause can be found in about 25% of those cases Studies have indicated that seminal vesicle secretion functions as an optimizer of fertilization The Zn2+ binding protein semenogelin I (SgI) represents a major fraction of the proteins present in seminal vesicle fluid and it serves as a structural component of the coagulum that is formed after ej

The risk of gestational diabetes mellitus (GDM) increases substantially with increasing maternal body mass index (BMI). The aim of the present study was to evaluate the relative importance of maternal BMI and glucose levels in prediction of large-for-gestational-age (LGA) births.

Recension av Ingrid Carlberg, ”Det står ett rum här och väntar på dig…” Berättelsen om Raoul Wallenberg och Bengt Jangfeldt, Raoul Wallenberg – en biografi.

The isomerization of 1,1'-diethyl-2,2'-cyanine iodide in n-alcohols is studied by femtosecond pump-probe spectroscopy. Using a broad range of probe wavelengths, the dynamics of ground-state bleach recovery, excited-state absorption and stimulation emission are monitored. We attributed the observed spectral evolution to the excited-state torsional motion, which occurs in a barrierless fashion in al

The dissertation deals with the construction of norms of academic excellence in the Swedish discipline of history 1900-1945. The area of focus is the competition for professorial chairs in history. The legacy of the discipline viewed history as a holistic concept, binding together most humanistic disciplines. From the perspective of this legacy, the view of empirical specialization was becoming in

A model-independent search for deviations from the Standard Model prediction is performed using the full e(+/-) p data sample collected by the H1 experiment at HERA. All event topologies involving isolated electrons, photons, muons, neutrinos and jets with transverse momenta above 20 GeV are investigated in a single analysis. Events are assigned to exclusive classes according to their final state.

This paper describes various examples of blatant attempts to suppress and censor parapsychology research and those who are doing it. The examples include raising false accusations, barring access to journals, suppressing papers and data, and ostracizing and persecuting scientists interested in the topic. The intensity of fear and vituperation caused by parapsychology research is disproportionate e

Frataxin is a mitochondrial protein with a central role in iron homeostasis. Defects in frataxin function lead to Friedreich's ataxia, a progressive neurodegenerative disease with childhood onset. The function of frataxin has been shown to be closely associated with its ability to form oligomeric species; however, the factors controlling oligomerization and the types of oligomers present in soluti

In this report, we present the results from a systematic benchmarking of four different long neutron guide geometries: elliptic, parabolic, ballistic (piecewise linearly focusing/defocusing), and straight, for various wavelength, divergence restriction, and guide length settings. In this work, we mapped relevant parts of the neutron phase space to show where advanced guide geometries have signific

Hierarchical depth culling is an important optimization, which is present in all modern high performance graphics processors. We present a novel culling algorithm based on a layered depth representation, with a per-sample mask indicating which layer each sample belongs to. Our algorithm is feed forward in nature in contrast to previous work, which rely on a delayed feedback loop. It is simple to i

Objective: Dietary linoleic acid, an n-6 polyunsaturated fatty acid, is metabolised to arachidonic acid, a component of colonocyte membranes. Metabolites of arachidonic acid have pro-inflammatory properties and are increased in the mucosa of patients with ulcerative colitis. The aim of this investigation was to conduct the first prospective cohort study investigating if a high dietary intake of li

Background. The question is debated on whether maternal hypothyroidism or use of thyroxin in early pregnancy affects the risk for infant congenital malformations. Objectives. To expand the previously published study on maternal thyroxin use in early pregnancy and the risk for congenital malformations. Methods. Data from the Swedish Medical Birth Register were used for the years 1996-2011 and infan

We investigate, through osmotic pressure measurements, the validity of the single-parameter equation of state (EOS) for solutions of polyethylene glycols in water, by Cohen et al.(1,2) We show that it is physically meaningful and that a reasonable good correspondence between the osmotic pressures for PEG35 in large range of concentrations is obtained. We also take the chain length dependence into

Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The most widespread underlying genetic deficiency is a heterozygous deficiency of the serine protease inhibitor Cl esterase inhibitor (C1-Inh). In addition to low C4 levels, the most important laboratory parameter for correct diagnosis of HAE or angioedema du

In this paper, we propose a practical and efficient method for finding the globally optimal solution to the problem of determining the pose of an object. We present a framework that allows us to use point-to-point, point-to-line, and point-to-plane correspondences for solving various types of pose and registration problems involving euclidean (or similarity) transformations. Traditional methods su

We use a strong two-colour laser field composed of the fundamental (800 nm) and the second harmonic (400 nm) of an infrared (IR) laser field to generate attosecond pulses with controlled spectral and temporal properties. With a second-harmonic intensity equal to 15% of the IR intensity the second-harmonic field is strong enough to significantly alter and control the electron trajectories in the ge