This study investigates summer high temperature extremes (HTEs) in southeast China and their linkage with the El Nino-Southem Oscillation (ENSO) and atmospheric circulations in the East Asian summer monsoon (EASM). An interdecadal change in HTEs associated with the abrupt shift of the ENSO monsoon climate in the late 1980s is demonstrated. Before this interdecadal shift, the interannual variabilit

Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. M1 protein challenge can cause widespread microthrombosis, suggesting a role of platelets in streptococcal sepsis. Herein, we hypothesized that platelets may play a role in M1 protein-induced lung inflammation and injury. M1 protein was injected intravenously in C57Bl/6 mice. For platelet and n

We report a population based case-control study of exposure to pesticides as risk factor for non-Hodgkin lymphoma (NHL). Male and female subjects aged 18-74 years living in Sweden were included during December 1, 1999, to April 30, 2002. Controls were selected from the national population registry. Exposure to different agents was assessed by questionnaire. In total 910 (91 %) cases and 1016 (92%)

Surgery in infants and young children with haemophilia, when preceded by accurate diagnosis and accompanied by safe and effective factor prophylaxis, is not associated with a significant risk of haemorrhage. Haemophilic newborns undergoing circumcision or major surgery prior to diagnosis and in the absence of appropriate haemostatic prophylaxis remain as a concern. Inhibitor development has replac

Background: Low plasma glutamine concentration is an independent prognostic factor for an unfavourable outcome in the intensive care unit (ICU). Intravenous (i.v.) supplementation with glutamine is reported to improve outcome. In a multi-centric, double-blinded, controlled, randomised, pragmatic clinical trial of i.v. glutamine supplementation for ICU patients, we investigated outcomes regarding s

What do we know about the prevalence and the specific features of autism spectrum disorders (ASDs) among subjects in forensic psychiatry and special youth centres? A clinical case series consisting of 42 subjects with ASD, recruited from three well-characterized populations in forensic psychiatry and special youth care, was used to determine: 1) the prevalence of ASD in these institutions (at leas

To provide practical guidelines for the cytopathologic diagnosis of malignant mesothelioma (MM). Cytopathologists involved in the International Mesothelioma Interest Group (IMIG) and the International Academy of Cytology (IAC), who have an interest in the field contributed to this update. Reference material includes peer-reviewed publications and textbooks. This article is the result of discussion

Neural devices may play an important role in the diagnosis and therapy of several clinical conditions, such as stroke, trauma or neurodegenerative disorders, by facilitating motor and pain control. Such interfaces, chronically implanted in the CNS, need to be biocompatible and have the ability to stimulate and record nerve signals. However, neural devices of today are not fully optimized. Nanostru

The programmability of modern graphics processing units (GPUs) provide great flexibility for creating a wide range of advanced effects for interactive graphics. Developing such effects requires writing not only shader code to be executed by the GPU but also supporting code in the application where the effect is to be used. This support code creates dependencies between effects and the applications

The mechanisms driving the development of immunoglobulin E (IgE) antibody repertoires are a matter of debate. Alternatives to the classical view on antibody development, involving somatic mutation and antigen-driven selection of high-affinity variants in germinal centers, have been proposed. Methods: We have re-analyzed the pattern of mutations in previously isolated and characterized human clonal

Cerebral intraventricular haemorrhage (IVH) is the most common cause of severe neurologic impairment following preterm birth in human infants. Ideally, an animal model for cerebral IVH should allow for reliable noninvasive evaluation of haemorrhagic extension and of subsequent development of posthaemorrhagic ventricular dilatation (PHVD). The aim of this study was to evaluate the use of high-frequ

The role of implantable neuromodulation systems and spinal cord stimulation in the management of pain is described. Recommendations of the American Society of Anesthesiologists Task Force on Chronic Pain Management and the American Society of Regional Anesthesia and Pain Medicine as they relate to spinal cord stimulation are discussed. This feature is adapted from paineurope 2012; Issue 1, ©Haymar

The author explores the relationship between science and truth in forensic crime fiction by analysis of narrative and media specific constituents of CSI: Crime Scene Investigation and Cornwell’s The Scarpetta Factor. Both are found to convey strong bonds between science and truth, and readers/viewers are likely to assume that this is the case also in the external world.

A nonintrusive three-dimensional trap for microscopic particles in a Liquid is described. The trap is based on acoustic radiation forces in an ultrasonic confocal standing-wave cavity. Experiments at 11 MHz demonstrate the concept and verify the theoretically calculated forces. Theoretical calculations for higher-frequency systems indicate a significant potential for low-rms-displacement trapping