Detailed chemical abundance distributions for 14 elements are derived for eight high-probability stellar members of the solar metallicity old open cluster M67 with an age of ∼4 Gyr. The eight stars consist of four pairs, with each pair occupying a distinct phase of stellar evolution: two G dwarfs, two turnoff stars, two G subgiants, and two red clump (RC) K giants. The abundance analysis uses near

Pharmacogenetics or pharmacogenomics approaches are important for addressing the individual variabilities of drug efficacy especially in the era of precision medicine. One particular interesting gene to investigate is APOA5, which has been repeatedly linked with the inter-individual variations of serum triglycerides. Here, we explored APOA5-statin interactions in 195 Chinese subjects randomized to

Objectives: Left ventricular ejection fraction (EF) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are important surrogate markers of cardiac function and wall stress. Randomized trials of heart failure (HF) have shown improvements in survival in patients with reduced EF (50%) was rare (14.1% of patients with HFrEF and 26.7% with HFmrEF), some degree of improvement was observed in 57.7%

Pulmonary hypertension (PH) is a lethal condition, and current vasodilator therapy has limited effect. Antiproliferative strategies targeting platelet-derived growth factor (PDGF) receptors, such as imatinib, have generated promising results in animal studies. Imatinib is, however, a nonspecific tyrosine kinase inhibitor and has in clinical studies caused unacceptable adverse events. Further studi

Abstract: This chapter looks at the challenges of disaster governance in India. It highlights the problems of engaging the Armed Forces as the responder to disasters given the prevalent sociological dynamics within the communities. The Armed Forces in India have successfully responded to several catastrophes such as the Gujarat earthquake, the Indian Ocean tsunami, the Kashmir earthquake and the m

Study aim: Retrospective studies have demonstrated a worse outcome in breast cancer patients not developing leukopenia during adjuvant chemotherapy. The SBG 2000-1 is the first randomised trial designed to compare individually dosed chemotherapy without G-CSF support based on grade of toxicity to standard-dosed chemotherapy based on body surface area (BSA). Methods: Patients with early breast canc

The article analyses the contexts, arguments and paradoxes of thinking about cultural heritage in Sweden of the 2000s when the topic achieved broad societal relevance in traditional media, internet fora, political communication and academic research. The discussion focuses on four themes: the normative criticism paradigm that has been increasingly influential in the heritage sector in recent years

Objective: Diabetic foot ulceration (DFU) has the potential to deteriorate rapidly without prompt assessment and treatment. The aim of this study was to assess the referral patterns for DFU, from primary care to specialised diabetes foot care units. Method: A two-part, quantitative, online questionnaire was administered to GPs across four countries in Europe: France, the UK, Germany and Spain. The

Aims Carotid intima media thickness (CIMT) predicts cardiovascular (CVD) events, but the predictive value of CIMT change is debated. We assessed the relation between CIMT change and events in individuals at high cardiovascular risk. Methods and results From 31 cohorts with two CIMT scans (total n = 89070) on average 3.6 years apart and clinical follow-up, subcohorts were drawn: (A) individuals wit

Psychoanalytic concepts and theory have long served studies of consumption, from exposing unconscious motives to elucidating contemporary consuming desire. Sharing with psychoanalysis an interest in symbolic meanings, anthropological approaches have also contributed to the study of contemporary consumption and social life. In this article, we draw on both Freudian psychoanalysis and Douglas’s stru

Purpose – The purpose of this paper is to demonstrate that, important as reflexivity is, it does not constitute the gold standard of qualitative research. Instead the author makes a plea for the use of sociological imagination. Design/methodology/approach – The paper makes use of data from the ISI Web of Science database to demonstrate the increasing popularity of the concept of reflexivity. Findi

Recent advances in nanotechnology and the accompanying development oftechniques that operate and manipulate systems on the micro- and nanometer scale have driven the development of stochastic thermodynamics. This isa theory that can describe small systems far from equilibrium, where the fluctuations are of the same order of magnitude as the mean values. Stochasticthermodynamics can be used to prov