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Cartilage macromolecules in knee synovial fluid. Markers of the disease course in patients with acute oligoarthritis

OBJECTIVE To investigate the development of chronic joint symptoms in patients presenting with acute oligoarthritis including knee joint synovitis with effusion and explore whether prognostic information can be derived from initial synovial fluid concentrations of aggrecan and cartilage oligomeric matrix protein (COMP) for development of chronic joint symptoms. METHODS Retrospective follow up of

Changes in cartilage and bone metabolism identified by serum markers in early osteoarthritis of the knee joint

Bone scan and serum markers of bone and cartilage in patients with knee pain and osteoarthritis

Joint space width in the axial view of the patello-femoral joint: Definitions and comparisons with MR imaging

Increased serum levels of cartilage oligomeric matrix protein in chronic erosive arthritis in rats

Serum concentrations of cartilage oligomeric matrix protein and bone sialoprotein in hip osteoarthritis: A one year prospective study.

Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats

Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with osteoarthritis-related type II collagen gene COL2A1 mutation

Synergistic protection against cartilage destruction by low dose prednisolone and interleukin-10 in established murine collagen arthritis

Lower disease activity and disability in Swedish patients with rheumatoid arthritis in 1995 compared with 1978

The aim of this study was to evaluate differences in disease activity, disability, and medical treatment in consecutive patients with rheumatoid arthritis seen at the outpatient clinics in Malmö, in 1978 (n=148) and 1995 (n=164). The groups were similar with regard to age, gender, disease duration, and the proportion having had hip or knee replacement surgery. The patients in 1995 had lower values

Noncollagenous Proteins: Glycoproteins and Related Proteins

IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation.

Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis

Genetic control of arthritis in rats

Diagnosis of osteoarthritis in relation to molecular processes in cartilage: comment on the article by Clark et al.

Molecular markers for assessment of cartilage damage in rheumatoid arthritis

Up-regulation of cartilage oligomeric matrix protein at the onset of articular cartilage degeneration in a transgenic mouse model of osteoarthritis

Circulating collagen metabolites in systemic sclerosis. Differences between limited and diffuse form and relations to pulmonary involvement

Matrix Glycoproteins and Proteoglycans in Cartilage

Nya läkemedel mot reumatoid artrit : Förbättrade behandlingsmöjligheter ställer nya krav på sjukvårdsorganisationen