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Radiolabeling and Biotinylation of Internalizing Monoclonal Antibody Chimeric BR96: Potential Use for Extracorporeal Immunoadsorption.

In this thesis, methodology of radiolabeling and simultaneous biotinylation for internalizing monoclonal antibody (MAb) chimeric BR96 (chiBR96) have been investigated by using three element groups of potential therapeutic radionuclides iodine, indium and rhenium, and their different labeling methods. The biodistribution and kinetics of biotinylated and radiolabeled chiBR96 have been studied in col

Världen förändras

Klimatförändringarna gör världen successivt varmare, förändrar nederbördsmönster, höjer havsytenivån, med mera. Klimatet har redan förändrats och i alla fall en viss fortsatt förändring är oundviklig på grund av tidigare och pågående växthusgasutsläpp. Hur stora klimatförändringarna blir på sikt beror i första hand på beslut om och åtgärder för att minska vår klimatpåverkan, det vill säga utsläpp

The relationship between obstructed and unobstructed walking speed: Results from an evacuation experiment in a smoke filled tunnel

In order to increase the knowledge on human behavior in smoke, an evacuation experiment was performed in a road tunnel in Stockholm in July, 2014. The experiment included 66 participants, who individually were instructed to evacuate a smoke-filled tunnel. The experiment focused on measuring the participants’ walking speed in smoke-filled, as well as smoke-free parts of the tunnel. In addition, exi

Kalendariska tidsuttryck under senmedeltid och reformationstid

Övergången från den medeltida kyrkoårskalendariska dateringstypen till den nutida månadskalendariska kartläggs kvantitativt för danska och svenska i ett senmedeltida och 1500-tals-material. Också utvecklingen med hänsyn till de båda typernas struktur undersöks.

Den matematiska punkten

THE POINT has its point of departure in the indivisible point of mathematics. In Swedenborg's Principia rerum naturalium (1734) the mathematical points are given an ontological significance. The world appears when God, like an artist drawing with his pencil, gives motion to the point. The world consists of circulating points. With spider metaphors Swedenborg postulated that the world is built on m

Ancient Sculptures in the Royal Museum. The eighteenth-century Collection in Stockholm.

The volume is an introduction to the study of ancient marbles collected by Swedish royalty up to the turn of the 18th century. In 1794, two years after the death of King Gustav III, main collector of the preserved marbles, a selected part of the sculptures were put to display in public museum. The main themes treated are as follows: the history of collecting, the function and agencies of the Roman

Future drug treatment of Type 1 diabetes

Insulin replacement therapy is considered the only effective and feasible treatment for type 1 diabetes mellitus (T1DM) as only insulin is capable of reversing the metabolic disturbances and restoring a near - normal quality of life in patients with T1DM. Despite rigorous measures and major advances in health care provided for patients with T1DM, increased morbidity and mortality are still common

An alternative approach to interpolated array processing for uniform circular arrays

In this paper, we propose an alternative approach to array interpolation for the sectorized array processing of a uniform circular array. While other approaches do not fully consider the influence of out-of-sector signals on the in-sector response, our approach explicitly addresses this issue. By controlling the out-of-sector response, our interpolated array demonstrates a significantly improved a

Analytical Pyrolysis - Studies of Sulfur in Coal and Pulp

Sulfur in coal and pulp have been characterized using pyrolysis–gas chromatography with a sulfur-selective flame photometric detector (Py–GC/FPD). The samples (50–150 µg) were pyrolyzed at temperatures between 300 and 1400°C usually followed by a combustion in oxygen at high temperature (>1000°C). The main sulfur-containing products were low-molecular compounds such as H2S, COS, SO2, CH3SH and CS2