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Complex avoidance behavior and its neurochemical regulation in the land snail Cepea numerals

.1. In hot plate experiments, the pulmonate land snail Cepaea nemoralis displays a biphasic passive/active avoidance behaviour composed of retraction and subsequent searching mediated by antagonistic muscular systems. The switch, between the behaviours, is under neuronal control.2.2. Leu- and met-enkephalin, as well as FMRFamide-antiserum, attenuated the retraction response and potentiated the sea

Coordinated integrin activation by actin-dependent force during T-cell migration

For a cell to move forward it must convert chemical energy into mechanical propulsion. Force produced by actin polymerization can generate traction across the plasma membrane by transmission through integrins to their ligands. However, the role this force plays in integrin activation is unknown. Here we show that integrin activity and cytoskeletal dynamics are reciprocally linked, where actin-depe

CFD analysis on flow resistance characteristics of six-start spirally corrugated tube

Heat transfer enhancement technology has been widely used in heat exchangers. The six-start spirally corrugated tube is a novel heat transfer tube, and its flow resistance characteristics have not been studied. In this paper, the flow resistance characteristics of the six-start spirally corrugated tube are studied. Specifically, the effect of influencing factors such as geometric parameters (pitch

CFD analysis on the dynamic flow characteristics of the pilot-control globe valve

The pilot-control globe valve (PCGV) is a new kind valve with simple structures and low driving energy consumption. It can utilize the pressure difference before and after the valve to control the action of the valve core. However, systematic theoretical research and numerical analysis are deficient at present. In this paper, the mathematical model of PCGV is established and Computational Fluid Dy

Survival of entrepreneurial firms : the role of agglomeration externalities

This paper analyzes the role of various types of agglomeration externalities on the survival rate of entrepreneurial firms. In particular, we trace the population cohort of newly-established and self-employed Swedish firms in the Knowledge-Intensive Business Service sector in 1997 up to 2012 and investigate the role of Marshallian and Jacobian externalities on the survival of these firms. We find

Haplotype analysis of identical factor IX mutants using PCR

We have detected the mutations in the factor IX genes from all of the haemopllilia B patients registered at Malmo haemophilia centre (45) and are currently examining the entire UK haemophilia B population. From these studies we have found 13 base substitutions which have recurred in 1-6 other, presumably unrelated, patients. In order to determine the minimum number of independent repeats of each m

Implantable central venous catheter facilitates prophylactic treatment in children with haemophilia

Twelve children with a severe form of haemophilia A received a totally implantable venous access system (Port-A-Cath) to facilitate regular prophylactic treatment with factor VIII. The indication for implantation was difficulty in obtaining regular access to a peripheral vein. Postoperative bleeding around the portal site occurred in two of 12 cases. After a median duration of follow-up of 26 mont

Neuropsychological findings in frontal lobe dementia

Neuropsychological investigations were performed on 18 patients with a clinical diagnosis of frontal lobe dementia supported by regional cerebral blood flow measurements. Nature and degree of cognitive impairment were examined with a comprehensive test battery. The results of the neuropsychological assessment could be described as three levels of cognitive impairment. The increasing levels of cogn

Neuropsychological tests as discriminators between dementia of Alzheimer type and frontotemporal dementia

The aim of this study was to examine whether cognitive test performance alone could distinguish patients with dementia of Alzheimer type (DAT) from those with frontotemporal dementia (FTD). Scores from three neuropsychological tests were used as discriminating variables in 28 cases with postmortem verified diagnoses. The selected tests measured verbal ability, visuospatial ability and verbal memor

Migratory blackcaps can use their magnetic compass at 5 degrees inclination, but are completely random at 0 degrees inclination

It is known that night-migratory songbirds use a magnetic compass measuring the magnetic inclination angle, i.e. the angle between the Earth's surface and the magnetic field lines, but how do such birds orient at the magnetic equator? A previous study reported that birds are completely randomly oriented in a horizontal north-south magnetic field with 0° inclination angle. This seems counter-intuit

Concentration-Induced Association in a Protein System Caused by a Highly Directional Patch Attraction

Self-association of the protein lactoferrin is studied in solution using small-angle X-ray scattering techniques. Effective static structure factors have been shown to exhibit either a monotonic or a nonmonotonic dependence on protein concentration in the small wavevector limit, depending on salt concentration. The behavior correlates with a nonmonotonic dependence of the second virial coefficient

Oberoendet inget frikort

Att göra problemen i Riksrevisionens ledning enbart till en fråga om felrekryteringar, såsom Gunnar Axen gör i sin replik, är att göra det lätt för sig. Riksrevisorerna i Sverige har betydligt mer makt än riksrevisorer i övriga nordiska länder. Det finns därför en gräns för hur fritt spelrum de bör ha. Oberoende ska inte föranleda beröringsskräck och det vaccinerar inte mot ansvar. Oberoende ska i