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Anti-inflammatory properties of micropatterned titanium coatings

Prolonged inflammation and reactive oxygen species (ROS) generated around an implanted biosensor are the primary causes of the foreign body response, including encapsulation of biosensor membranes. We have previously demonstrated that TiO2 surfaces reduce ROS. Here we investigated the potential of using the anti-inflammatory properties of TiO2 in the design of biosensor membranes with improved lon

Experimental quantum-state tomography of a solid-state qubit

Quantum-state tomography is used to characterize the state of an ensemble based qubit implemented through two hyperfine levels in Pr3+ ions, doped into a Y2SiO5 crystal. We experimentally verify that single-qubit rotation errors due to inhomogeneities of the ensemble can be suppressed using the Roos-Molmer dark-state scheme [Roos and Molmer, Phys. Rev. A 69, 022321 (2004)] Fidelities above > 90%,

Structure elucidation of the hepatitis B virus encapsidation signal by NMR on selectively labeled RNAs.

Hepatitis B virus (HBV) HBV is DNA virus with a unique replication strategy, which involves reverse transcription of its pregenomic RNA. Essential for this reverse transcription are the 5'- and 3'-ends of its pregenomic RNA (5'-RT-RNA and 3'-RT-RNA, respectively) which form conserved bulged stem-loop structures. The 5'-RT-RNA consists of a 67 nucleotide bulged stein-loop structure, epsilon, which

Multifocal electroretinography (mfERG) in insulin dependent diabetics with and without clinically apparent retinopathy

Purpose: To Study the retinal function, using multifocal electroretinography (mfERG), in diabetic patients with mild and moderate retinopathy, and in diabetics without clinically apparent retinopathy. Methods: Thirty-one patients with insulin dependent diabetes mellitus, eleven without any clinically apparent retinopathy, twelve with mild retinopathy and eight with moderate retinopathy, were studi

HIV/hepatitis coinfection in eastern Europe and new pan-European approaches to hepatitis prevention and management

Issues: HIV/hepatitis coinfection in Europe; WHO European clinical protocols on the management of people coinfected with HIV/AIDS and hepatitis B or C (HBV or HCV); stakeholder recommendations for better HCV services. Introduction: The increasing availability of highly active antiretroviral therapy throughout Europe and central Asia has changed comorbidity and mortality patterns among people livin

Enzymatic and chemical synthesis of phosphatidylcholine regioisomers containing eicosapentaenoic acid or docosahexaenoic acid

Regioselective incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into phosphatidylcholine (PC) was carried out using enzymatic and chemical synthesis. Incorporation at the sn-1 position was successfully achieved by lipase-catalysed esterification of 2-palmitoyl-lysophosphatidylcholine (LPC), although in most cases, the enzymes incorporated EPA and DHA at lower rates than

Female call preferences in tree-hole frogs: why are there so many unattractive males?

In tree-hole frogs, Metaphrynella sundana, the fundamental call frequency varies widely between males. In field playback experiments, females strongly preferred calls from the lower range of frequencies found in the population. There was no correlation, however, between male size and call frequency, as is normally the case for anurans, so large males were not necessarily more attractive to females

Extraction of cadmium from phosphoric acid solutions with amines. Part III. A thermodynamic extraction model

A thermodynamic model for cadmium extraction from phosphoric-hydrochloric acid mixtures has been developed. The model enables calculations of cadmium extraction as well as coextraction of phosphoric and hydrochloric acids to be made. In the aqueous phase Bromley's model for the activity coefficients is adopted. In the organic phase simple expressions for the non-ideal behaviour of phosphoric acid

Extending the Light-Harvesting Properties of Transition-Metal Dendrimers

We report a study of the electronic energy-transfer dynamics within the transition-metal polypyridine complex OsRu3pyr6 (Os[(dpp)Ru(bpy{pyrene})2]38+, where dpp=2,3-bis(2-pyridyl)pyrazine and bpy=2,2-bipyridine) after excitation with UV light. By using a broadband visible femtosecond probe, we are able to simultaneously detect both the energy transfer from the peripheral aromatic ligands to the Os

Magnetic resonance imaging of the knee in chronic knee pain. A 2-year follow-up

Objective: The aim of the study was to evaluate the change over time of cartilage defects, subchondral lesions and meniscal abnormalities of the knee using magnetic resonance (MR) imaging with a 2-year interval in patients with chronic knee pain. Design: In the format of a prospective study of early osteoarthritis (OA), the signal knee (most painful at the inclusion in the study 1990) in 47 indivi

Effect of temperature in long-term preservation of vascular endothelial and smooth muscle function

BACKGROUND. In clinical transplantation the donor organ is perfused with a cold preservation solution to obtain quick core cooling and a suitable environment for the tissue cells. Without good preservation of the vasculature, progressive deterioration of the blood flow during reperfusion may ultimately lead to the no-reflow phenomenon, even though the function of the other cells in the organ may b

Mhc diversity in two passerine birds: no evidence far a minimal essential Mhc

Humans express an array of Mhc genes, while the chicken has an Mhc that is relatively small and compact with fewer expressed genes. Here we ask whether the "minimal essential Mhc" of the chicken is representative for birds. We investigated the RFLP genotypes in 55 great reed warblers Acrocephalus arundinaceus and 10 willow warblers Phylloscopus trochilus to obtain an overview of the number of clas

Psychomotor functioning in suicide attempters. An explorative study using the Resource Oriented Body Examination of Bunkan

Within physical therapy there is a tradition of focusing on body-oriented resources and psychomotor functioning. The aim of the present explorative study was to describe psychomotor functioning such as patterns of muscular tension, posture, resistance to passive movements, respiration, and reactions to palpation in a group of suicide attempters admitted to the Lund Suicide Research Center, Sweden.

Long-term follow-up in depressed patients treated with ECT

Design: The aim was to study the long-term effects of electroconvulsive therapy (ECT) in depression. 55 patients were followed-up 20-24 years after an ECT series. 13 patients were still alive and 10 agreed to participate in the study. All 55 patients had been investigated with clinical and neuropsychological assessment and with neurophysiological measurements; regional Cerebral Blood Flow (rCBF) a