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Novel methods of malignant brain tumor treatment utilizing the tumor microenvironment

Malignant brain tumors constitute a disaster in the lives of patients, either in the form of extremely low survival in glioblastoma, or the serious long-term adverse effects of therapy in medulloblastoma. These two tumor types represent the most common malignant brain entities in adults and children, respectively. Ever since the early 2000’s, no major improvement of patient outcomes occurred. Immu

Growth and Characterization of Core-Branch Nanowire Structures

This thesis investigates growth of III – V semiconductor nanowire (NW) arrays, in a core- branch architecture, with the aim to develop diffusion driven light emitting diodes (LED) on NWs. Diffusion driven LEDs are based on the concept of decoupling the active region from the p-n junction. The carriers are injected by diffusion in the active region, because of the bandgap difference between the pn

Coherentism

Perhaps the most fundamental question of epistemology asks on what grounds our knowledge of the world ultimately rests. The traditional Cartesian answer is that it rests on indubitable facts arrived at through rational insight or introspection. Coherentists reject this answer, claiming instead that knowledge arises from relations of coherence or mutual support: if our beliefs cohere, we can be sur

True infection or contamination in patients with positive Cutibacterium blood cultures-a retrospective cohort study

Cutibacterium is a genus often considered a contaminant when present in blood cultures, but it can also cause severe infections, especially related to implanted foreign materials. We investigated the incidence and features of patients with true Cutibacterium infection. Patients with positive Cutibacterium blood cultures between the years 2015-2020 in southern Sweden were identified through microbi

Electrophysiological signatures revealing the temporal dynamics of episodic retrieval

Episodic memory enables mental time travel, allowing us to relive specific, personally experienced events tied in time and place. This feat of human memory is considered to be dependent on the reinstatement of the cortical patterns that were active at the time of encoding. A growing body of recent literature has provided support for this idea by showing that retrieval success co-varies with the ne

The Health of Immigrant Youth in Denmark : Examining Immigrant Generations and Origin

First-generation migrants tend to have better health than those of native ancestry, while second-generation migrants often are affected by negative health assimilation. Less is known about immigrants arriving before their teens, the 1.5 generation, or those with one native and one immigrant parent, the 2.5 generation. We apply logistic regression models to study physical and mental health outcomes

The social care-taking of the city-kids. Determinants for day-care attendance in early twentieth century southern Sweden

In this paper, we analyze one of the early welfare interventions in the Swedish welfare state targeted towards mothers and young children: the introduction of a child day-care system. Because quantitative research on day-cares in historical settings is generally scarce, in this study, we focus on the determinants of day-care enrollment in southern Sweden during the early twentieth century. We use

Från chiffer till klartext? : Temamodellering av statliga offentliga utredningar 1945–1989

Denna artikel innehåller en analys av samtliga rapporter från Statens offentliga utredningar (SOU), 1945-89. Analysen applicerar metoder inom digital humaniora och inkluderar forskning gjort i en Jupyterlabbmiljö som utvecklats på Humlab på Umeå universitet. Artikeln är ett resultat av forskningsprojektet Välfärdsstaten analyserad, som ämnar att digitalisera litteratur, arbetar med datasäkring av In 2015 the National Library of Sweden finished digitising all Governmental Official Reports (SOU) from 1922 to 1999. Traditionally, SOU reports – and work performed within different governmental committees – were tasked with preparing the Swedish government for apt and rational decision-making. The range of subjects covered by governmental committees and SOU reports basically includes every area

Deviations from the extended London model at high magnetic fields in YBa2Cu3 O7

We report on the evolution with the magnetic field and the temperature of the vortex lattice (VL) in fully oxygenated YBa2Cu3O7 as studied by time-of-flight small-angle neutron scattering. Using the High Field Magnet/Extreme Environment Diractometer beamline at Helmholtz-Zentrum Berlin, we have obtained data up to 25.9 T - much higher than data available previously. Our VL structure results are co

Anti-Sufism in Early Qajar Iran : Āqā Muḥammad ‘Alī Bihbahānī (1732–1801) and His Risāla-yi khayrātiyya

With the revival of the Ni‘matullāhī Order in late eighteenth-century Iran, the confrontation between uṣūlī ‘ulamā’ and Sufis gained new momentum. While the relationship between official Iranian Shiism and organized Sufism had been strained since the rise of the Safavids, the firm establishment of uṣūlism among Shii ‘ulamā’ and the Sufi revival in the late eighteenth century initiated a polemical

Yearbook of Muslims in Europe : Volume 9

The Yearbook of Muslims in Europe is an essential resource for analysis of Europe's dynamic Muslim populations. Featuring up-to-date research from forty-six European countries, the reports provide cumulative knowledge of on-going trends and developments around Muslims in different European countries. In addition to offering a relevant framework for original research, the Yearbook of Muslims in Eur

Underwater source localization in the presence of strong interference

The underwater localization of a broadband target in the presence of strong interference and noise has been widely investigated. A novel clutter suppression approach based on oblique projections is proposed, exploiting the prior information of the expected target response. The method uses a generalised likelihood ratio formulation to select the oblique projection best matching the measured data. T