To follow the expression of the fourth enzyme of pyrimidine de novo synthesis dihydroorotate dehydrogenase (DHODH) in cells and tissues, we studied the DHODH mRNA expression by means of RT-PCR in rat tissues. Rabbit polyclonal anti-DHODH immunoglobulins were applied for immunochemical quantification of the enzyme protein by Western blotting. In mouse B-lymphocytes, which were adapted to tolerate u

The occurrence of a deoxyribonucleoside kinase in Drosophila melanogaster (Dm-dNK) with remarkably broad substrate specificity has recently been indicated (Munch-Petersen, B., Piskur, J., and Søndergaard, L. (1998) J. Biol. Chem. 273, 3926-3931). To prove that the capacity to phosphorylate all four deoxyribonucleosides is in fact associated to one polypeptide chain, partially sequenced cDNA clones

We present a software package, Modes, offering h-adaptive and p-adaptive linear multistep methods for first order initial value problems in ordinary differential equations. The implementation is based on a new parametric, grid-independent representation of multistep methods [Arévalo and Söderlind 2017]. Parameters are supplied for over 60 methods. For nonstiff problems, all maximal order methods (

Flotation is a separation process where particles or droplets are removed from a suspension with the aid of floating gas bubbles. Applications include dissolved air flotation (DAF) in industrial wastewater treatment and column froth flotation (CFF) in wastewater treatment and mineral processing. One-dimensional models of flotation have been limited to steady-state situations for half a century by

In mammals four deoxyribonucleoside kinases, with a relatively restricted specificity, catalyze the phosphorylation of the four natural deoxyribonucleosides. When cultured mosquito cells, originating from the malaria vector Anopheles gambiae, were examined for deoxyribonucleoside kinase activities, only a single enzyme was isolated. Subsequently, the corresponding gene was cloned and over-expresse

Sofi Qvarnström var lektor i retorik vid Lunds universitet. Hon avled i augusti 2018. Hon var en person som berörde många, både som akademiker och som medmänniska. Berättelser, retorik och medier samlar elva texter skrivna av vänner och kollegor till Sofi. Texterna tar sina utgångspunkter i hennes forskningsintressen, hennes lärargärning och i de existentiella frågor som väcks i samband med att en

hand in the fight against resistant microbes. This thesis discusses the feasibility and potential of specific immunotherapy in treating acute bacterial infections and chronic sequels. The infection model is acute cystitis; the most common form of urinary tract infection, affecting millions of patients annually. Susceptible patients develop the characteristic clinical manifestation of dysuria, urge

UNDER 1900-TALET blev Sverige världens jämlikaste land. Inkomstfördelningen var jämn, klassresorna många och det politiska deltagandet stort och relativt jämnt fördelat i befolkningen. Sverige var ett föregångsland som debatterades över hela världen som en förebild eller ett skräckexempel. Men hur kom det sig att just Sverige blev så jämlikt? Akademiker, debattörer och politiker över hela den poli

The public unemployment insurance program in Sweden has retrenched in terms of its benefit generosity in the last three decades. As a response to this trend in which an ever-smaller proportion of the previous income of unemployed persons is compensated by public unemployment insurance benefit, complementary income insurance schemes provided by unions have expanded rapidly in the last 15 years and

Background: Resting-state functional magnetic resonance imaging (fMRI) studies have demonstrated that basal ganglia functional connectivity is altered in Parkinson's disease (PD) as compared to healthy controls. However, such functional connectivity alterations have not been related to the dopaminergic deficits that occurs in PD over time. Objectives: To examine whether functional connectivity imp

This deliverable maps the prevailing polycentric settings of six studied countries. The studied countries are the partner countries for the NEWCOMERS project, i.e. Germany, Italy, the Netherlands, Slovenia, Sweden and the United Kingdom. In this report, the countries' polycentric settings will be described in relation to the polycentric framework developed in WP 2, with specific focus on the techn

Morgan Johansson vägrar utreda narkotikapolitiken och anser den svenska modellen överlägsen. Men problemet är alldeles för allvarligt för att ministerns förutfattade meningar ska få styra, skriver flera debattörer.

The effect of avoided crossings on the spectral profiles of resonant X-ray Raman scattering was investigated. The theory was also applied to nitrogen molecule in the core-excited level to analyze the electron decay process. The dependence of internuclear distance on electron transition amplitude was considered important with respect to the breakdown process of the transition. The correlation betwe