Background: Chronic nodular prurigo (CNPG) is a condition characterized by chronic itch, a prolonged scratching behaviour and the presence of pruriginous nodules. A comprehensive understanding of this condition, especially regarding its clinical characteristics and impact on quality of life is still lacking. Objectives: Aim of this pan-European multicentre cross-sectional study was to establish th

Natural history museums are unique spaces for interdisciplinary research and educational innovation. Through extensive exhibits and public programming and by hosting rich communities of amateurs, students, and researchers at all stages of their careers, they can provide a place-based window to focus on integration of science and discovery, as well as a locus for community engagement. At the same t

An extensive body of research has shown that episodic remembering involves spontaneous eye movements that largely reproduce the gaze patterns that were present during encoding (e.g. Brandt & Stark, 1997; Johansson, et al., 2006; 2012; Johansson & Johansson, 2014; Richardson & Spivey, 2000). We have further demonstrated that gaze positions showing compatibility between encoding and retr

The response of evapotranspiration (ET) to warming is of critical importance to the water and carbon cycle of the boreal biome, a mosaic of land cover types dominated by forests and peatlands. The effect of warming-induced vapour pressure deficit (VPD) increases on boreal ET remains poorly understood because peatlands are not specifically represented as plant functional types in Earth system model

Objective: To evaluate the effect of intrusive thoughts at diagnosis on quality of life, depressed mood and waking up with anxiety up to two years after radical prostatectomy. Method: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, longitudinal multicenter study of 4003 patients undergoing radical prostatectomy. Questionnaire data were collected preoperatively, at 3, 12

Purpose: This Position Paper aims to review and discuss the available data on therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill adult patients in the intensive care unit (ICU). This Position Paper also provides a practical guide on how TDM can be applied in routine clinical practice to improve therapeutic outcomes in critically ill adult patients. Me

Background: The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent consolidation therapy in newly diagnosed multiple myeloma. We therefore compared autologous HSCT with bortezomib–melphalan–prednisone (VMP) as intensification therapy, and bortezomib–lenalidomide–dexamethasone (VRD) consolidation the

Partially premixed combustion (PPC) has shown to produce high gross indicated efficiencies while yielding lower pollutant emissions, such as oxides of nitrogen and soot, than conventional diesel combustion. Gasoline fuels with a research octane number (RON) of 60-70 have been proposed as optimal for PPC as they balance the trade-off between ensuring good combustion stability at low engine loads an

In-cylinder heat losses in diesel engines reduce engine efficiency significantly and account for a considerable amount of injected fuel energy. A great part of the heat losses during diesel combustion presumably arises from the impingement of the flame. The present study compares the heat losses at the point where the flame impinges onto the piston bowl wall and the heat losses between two impinge

Background: Many genera and species of Streptococcus-like bacteria (SLB) can cause infective endocarditis (IE), but little is known about the epidemiology of and the risk factors for IE in SLB-bacteremia. The aim of the study was to analyze this in a cohort of patients with SLB-bacteremia, focusing on Abiotrophia, Aerococcus, Gemella, and Granulicatella. We also evaluated whether published scoring

Two dispenser types for pine sawfly (Hymenoptera: Diprionidae) pheromones-glass capillaries and dental cotton rolls-are described, and release rates reported. Glass capillaries of different diameters were used in field tests to determine dose-response relationships of (2 S,3 S,7 S)-3,7-dimethylpentadecan-2-yl acetate (diprionyl acetate), diprionyl propionate, and trans-perillenal on the trap catch

Context: Little is known about the individual response of glucose-regulating factors to administration of exogenous insulin infusion in extremely preterm infants. Objective: To evaluate longitudinal serum concentrations of insulin, C-peptide, and plasma glucose levels in a high-frequency sampling regimen in extremely preterm infants treated with insulin because of hyperglycemia. Design: Prospectiv

The chiral syntheses of some analogues, 2 - 7, of 3,7-dimethyl-2-pentadecanol, 1 (diprionol), and of the corresponding acetates are described. The acetate of 1 is the main attractant in the sex pheromone of the Neodiprion genus (Diprionidae). Compounds 2 /2- 4 were identified as minor components isolated from females of Neodiprion sertifer. Synthetic intermediates were prepared either from chiral

The pine sawfly pheromone precursor 3,7-dimethyl-2-pentadecanol (diprionol) was quantified by gas chromatography in different body parts of virgin female Neodiprion sertifer. About one-third of the total amount (approx. 10 ng per female) was found in each of head + thorax, abdominal segments 1-3, and the remaining abdomen. Diprionol was also found in the respective parts of pupae, but in lower amo

Ett universitets värde bestäms delvis av kvaliteten på de samtal som förs där. Utifrån vad vi vet om kreativa processer kan man anta att bra samtal leder till bra idéer som i sin tur leder till god utveckling på längre sikt.Men vilka förutsättningar krävs för att det goda samtalet ska kunna komma till stånd? Hur påverkas våra samtal och därmed våra samarbeten i Corona-tider när i stort sett all ve

This article explores the potential of combining high‐performance computing techniques and a set of integrated digital methods to investigate the cityscape of ancient Hermione, Greece. Unmanned aerial vehicles (UAVs), terrestrial laser scanning, image‐based modelling techniques and high‐performance computing have been combined to provide a fully‐three‐dimensional (3D) representation of the city la

All eight optical isomers of 3,7‐dimethyl‐2‐pentadecanyl acetate (diprionyl acetate), of high optical purity (>97.4%), were tested for a behavioural activity on male pine sawflies, Neodiprion sertifer (Geoffr.) (Hymenoptera: Diprionidae), in northern Europe. Males were strongly attracted to (2S, 3S, 7S)‐diprionyl acetate. Addition of more than 0.1% of the (2S, 3R, 7R)‐isomer reduced the catch and

Electroantennographic and single sensillum recordings were performed on male pine sawfly, Neodiprion sertifer, antennae. Responses to the sex pheromone component (2S, 3S, 7S)- 3,7-dimethyl-2-pentadecenyl (diprionyl) acetate (SSS:OAc), to the behavioral inhibitor (2S, 3R, 7R)-diprionyl acetate (SRR:OAc), to the six other enantiomers of diprionyl acetate, and to the biosynthetic precursor diprionol