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Cation and buffer specific effects on the DNA-lipid interaction

Knowledge of DNA - lipid layer interactions is key for the development of biosensors, synthetic nanopores, scaffolds, and gene-delivery systems. These interactions are strongly affected by the ionic composition of the solvent. We have combined quartz crystal microbalance (QCM) and ellipsometry measurements to reveal how pH, buffers and alkali metal chloride salts affect the interaction of DNA with

Obstructive sleep apnoea heterogeneity and cardiovascular disease

Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease (CVD), and is therefore important to consider in the prevention and management of CVD. Observational studies indicate that OSA is a risk factor for incident hypertension, poorly controlled blood pressure, stroke, myocardial

Om tillit till polisen – En idéanalys av offentlig debatt under några tidsperioder med låg grad tillit till institutionen

This essay is about trust in the police organization at two time periods, the mid - and late 1990s and 2010s. In these periods the national polls pointed at a weaker experienced trust in the police compared to other time periods. Trust in the national institutions is of importance to the democratic system. National polls are however very seldom complemented by studies based on qualitative methods

Captive offshoring, innovation and market diffusion : evidence from the Swedish Community Innovation Survey

Although the effects of captive offshoring on firm innovation have increasingly become a subject of study, the literature did so far not distinguish between the effects on introducing innovation as opposed to the effects their market diffusion. This distinction is important. By integrating insights from the innovation diffusion literature, we argue that the effects of captive offshoring on home ba

Rectal washout in rectal cancer surgery

BackgroundRectal washout (RW) is performed to eliminate intraluminal cancer cells and thereby reducing the risk of local recurrence (LR). The overall aim of this thesis was to investigate the importance of RW in rectal cancer surgery.MethodPaper I: Survey of the current practice of RW among Swedish colorectal units.Paper II: The association between RW and 30-day postoperative complications after a

Recombinant Protein Production Using the Baculovirus Expression Vector System (BEVS)

The baculovirus expression vector system (BEVS) is one of the most popular eukaryotic systems for recombinant protein production. The focus of our protein production platform is the provision of recombinant proteins for research use, where generally only small quantities are required, in the range of tens of micrograms to a few hundred milligrams. Here, we present methods that reflect our standard

Terminating Apartheid's Atomic Bomb

South Africa secretly produced six and a half nuclear weapons from 1978-1989 before undertaking a complete nuclear disarmament between 1989-1991; it is the only instance in history of when a state has discarded an indigenously developed nuclear arsenal and presents a unique case for studying the nuclear decision-making of states. This thesis is a theory-testing case study where I, by conducting a

Building Dynasties, Shaping States : Dynasty and State Formation in Early Modern Europe

The introduction discusses the concepts of dynasty and state formation and their interrelated nature. It stresses the need to def ine the concept of dynasty as a kinship group with an acute sense of historical continuity, claiming the right to rule a certain territory and manifesting this claim in political, social and cultural ways; and the related concept of dynasty formation as the acts, consci

Dynastic Marriage Spheres in Early Modern Europe : A Comparison of the Danish Oldenburgs and Three Houses of the Empire

Princely marriages are here seen as a key component in dynasty formation and dynasty securing. The marriages of the Danish royal house and three houses of the Empire are studied for the period c. 1530–1700. Most of them took place within what can be labelled a Scandinavian-German-Lutheran marriage sphere. It was a highly hierarchized sphere with little contact between top (royal and electoral hous

Releasing high positive end-expiratory pressure to a low level generates a pronounced increase in particle flow from the airways

Objectives: Detecting particle flow from the airways by a non-invasive analyzing technique might serve as an additional tool to monitor mechanical ventilation. In the present study, we used a customized particles in exhaled air (PExA) technique, which is an optical particle counter for the monitoring of particle flow in exhaled air. We studied particle flow while increasing and releasing positive

Methodological lessons for negotiating power, political capabilities, and resilience in research on climate change responses

Critical scholarship on the intersection of development pathways and climate change responses highlights the roles of power, agency, social difference, intersecting inequalities, and social justice in shaping people's resilience in a rapidly transforming world. Yet, how to precisely increase the spaces in which people experiencing marginalisation can address power asymmetries and strengthen their

The role of internal and external moderation for assuring academic standards

Drawing on the review of quality assurance policies in higher education already set out of the introduction, this chapter explores the impact of national quality assurance processes adopted to aid consistency in the judgement of academic standards in UK higher education. Specifically, it will examine the ways in which the processes adopted to support marking and to moderate marks, known collective