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No more faith in fakes : A natural history of counterfeiting

Commenting on Eco's papers about fakes, I claimed that what is meant by a fake depends on what is taken to be the original, and this, in turn, revolves around the relation between type and token. As observed by Prieto and Grice, a sign, apart from the content it conveys, also carries a message informing us that it is a sign. The scare crow is a sign to the addresser, but not, ideally, to the addre

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Si la traducción es un acto de transacción de sentidos, la semiótica debeser capaz de definir su especificidad en relación con otros actos semióticos. En lugar de eso, siguiendo a las sugerencias de Roman Jakobson, de la escuela de Tartú y, de forma implícita, de Charles Sanders Peirce, la noción de traducción ha sido generalizada para cubrir más o menos todas las operaciones que se pueden llevar

Physical vs. virtual agent embodiment and effects on social interaction

Previous work indicates that physical robots elicit more favorable social responses than virtual agents. These effects have been attributed to the physical embodiment. However, a recent meta-analysis by Li [1] suggests that the benefits of robots are due to physical presence rather than physical embodiment. To further explore the importance of presence we conducted a pilot study investigating the

Daily duration of long-term oxygen therapy and risk of hospitalization in oxygen-dependent COPD patients

Introduction: Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily duration of LTOT (24 vs 15 h/d) and hospital admissions in patients with LTOT due to

Mechanisms Underlying Aggressive Behavior Induced by Antiepileptic Drugs : Focus on Topiramate, Levetiracetam, and Perampanel

Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by adverse effects, among them psychiatric and behavioral ones including aggressive behavior (AB). Knowledge of the incidence, risk factors, and the underlying mechanisms of AB induced by AEDs may help to facilitate management and reduce the risk of such side effects. The exact incidence of AB as an adverse e

Experimental study on CFRP-reinforced glulam-concrete composite beams

To investigate the mechanical behaviour of timber-concrete composite (TCC) beams strengthened with carbon fibre-reinforced polymer (CFRP), one TCC beam without CFRP and three TCC beams with different thickness of CFRP were tested under four point bending. During the loading process, the deformation development and failure mode of the composite beams were observed. The strain distribution at mid-sp

Effect of Levothyroxine Treatment on Incident Dementia in Adults with Atrial Fibrillation and Hypothyroidism

Background and Objective: The possible adverse or positive effects of levothyroxine treatment among patients with atrial fibrillation have been debated. Atrial fibrillation, levothyroxine treatment, and dementia are common among older adults, yet little is known about the effects of levothyroxine on the development of dementia. Methods: The study population included all adults (n = 12,057) aged ≥

Novel tau fragments in cerebrospinal fluid : relation to tangle pathology and cognitive decline in Alzheimer’s disease

Tau is an axonal microtubule-binding protein. Tau pathology in brain and increased tau concentration in the cerebrospinal fluid (CSF) are hallmarks of Alzheimer’s disease (AD). Most of tau in CSF is present as fragments. We immunoprecipitated tau from CSF and identified several endogenous peptides ending at amino acid (aa) 123 or 224 using high-resolution mass spectrometry. We raised neo-epitope-s

MIMO Nyquist interpretation of the large gain theorem

The Large Gain Theorem is an input-output stability result with intriguing applications in the field of control systems. This paper aims to increase understanding and appreciation of the Large Gain Theorem by presenting an interpretation of it for linear time-invariant systems using the well-known Nyquist stability criterion and illustrative examples of its use. The Large Gain Theorem is complemen

Tangency portfolio weights for singular covariance matrix in small and large dimensions : Estimation and test theory

In this paper we derive the finite-sample distribution of the estimated weights of the tangency portfolio when both the population and the sample covariance matrices are singular. These results are used in the derivation of a statistical test on the weights of the tangency portfolio where the distribution of the test statistic is obtained under both the null and alternative hypotheses. Moreover, w

Microstructures of cellulose coagulated in water and alcohols from 1-ethyl-3-methylimidazolium acetate : contrasting coagulation mechanisms

Abstract: Coagulation of cellulose solutions is a process whereby many useful materials with variable microstructures and properties can be produced. This study investigates the complexity of the phase separation that generates the structural heterogeneity of such materials. The ionic liquid, 1-ethyl-3-methylimidazolium acetate ([C2mim][OAc]), and a co-solvent, dimethylsulfoxide (DMSO), are used t

Shocked quartz grains in the early Cambrian Vakkejokk Breccia, Sweden—Evidence of a marine impact

Here we present a study of the abundance and orientation of planar deformation features (PDFs) in the Vakkejokk Breccia, a proposed lower Cambrian impact ejecta layer in the North-Swedish Caledonides. The presence of PDFs is widely accepted as evidence for shock metamorphism associated with cosmic impact events and their presence confirms that the Vakkejokk Breccia is indeed the result of an impac

Water Body Extraction From Very High-Resolution Remote Sensing Imagery Using Deep U-Net and a Superpixel-Based Conditional Random Field Model

Water body extraction (WBE) has attracted considerable attention in the field of remote sensing image analysis. Herein, we present an enhanced deep convolutional encoder-decoder (DCED) network (or Deep U-Net) specifically tailored to WBE from remote sensing images by applying superpixel segmentation and conditional random fields (CRFs). First, we preclassify the entire remote sensing image into th

Common marmosets are sensitive to simple dependencies at variable distances in an artificial grammar

Recognizing that two elements within a sequence of variable length depend on each other is a key ability in understanding the structure of language and music. Perception of such interdependencies has previously been documented in chimpanzees in the visual domain and in human infants and common squirrel monkeys with auditory playback experiments, but it remains unclear whether it typifies primates