The brainstem origin of preganglionic fibers to the sphenopalatine ganglion in rat was revealed by the aid of the retrograde axonal tracer True Blue (which does not traverse to a second order neuron) applied deep in the sphenopalatine ganglion or the Vidian nerve on one side. The majority of fibers originate in the ipsilateral lacrimo-muconasal nucleus in the ventrolateral rostral medulla oblongat

Different studies on the stability of high density lipoprotein cholesterol (HDL) in frozen serum or plasma have yielded conflicting results, namely increase, decrease, or no change at all during prolonged storage under freezing conditions. As part of a major trial on lipid-lowering strategies we statistically demonstrated a time-related decrease in HDL cholesterol during storage up to 46 months at

Endoderm development is an area of intense interest in developmental biology, but progress has been hampered by the lack of specific markers for differentiated endodermal cells. In an unbiased secretion cloning screen of Xenopus gastrula embryos we isolated a novel gene, designated Darmin. Darmin encodes a secreted protein of 56 kDa containing a peptidase M20 domain characteristic of the glutamate

Ethanol produced from various lignocellulosic materials such as wood, agricultural and forest residues has the potential to be a valuable substitute for, or complement to, gasoline. One of the major resources in the Northern hemisphere is softwood. This paper reviews the current status of the technology for ethanol production from softwood, with focus on hemicellulose and cellulose hydrolysis, whi

PURPOSE: Activation of soluble guanylate cyclase with a subsequent increase in intracellular levels of cyclic guanosine monophosphate is necessary for normal erection. In vascular tissue 3(5'-hydroxymethyl-2'-furyl-1-benzyl indazole (YC-1) (Abbott Laboratories, North Chicago, Illinois) has been shown to stimulate soluble guanylate cyclase independent of nitric oxide. We studied whether YC-1 modula

Adsorption of a model protein to a surface with end-grafted polymers was studied by Monte Carlo simulations. In the model the effect on protein adsorption in the presence of end-grafted polymers was evaluated by calculating the change in free energy between an end-grafted surface and a surface without polymers. The change in free energy was calculated using statistical mechanical perturbation theo

Sphingosine 1-phosphate (SPP) is associated with the regulation of apoptosis, although its role in neutrophil apoptosis remains poorly investigated. Here, we show that exogenous SPP antagonizes spontaneous and anti-Fas-induced apoptosis in neutrophils. Pre-treatment with pertussis toxin clearly reduced the apoptosis-inhibiting capacity of SPP. Consequently, we investigated the involvement of poten

Popular Abstract in Swedish Havandeskapsförgiftning (preeklampsi) är ett allvarligt risktillstånd som uppkommer vid 1.5-2.0 % av alla graviditeter och sjukdomen är en av de största orsakerna till mödra- och barndödlighet i världen. Preeklampsi karaktäriseras av högt blodtryck och läckage av äggvita i urinen under sista hälften av graviditeten hos en tidigare frisk kvinna. Njurarna spelar en avgöraThe aim of the research presented in this thesis was to provide extended background knowledge concerning several biochemical markers, used for the medical evaluation of pregnant women with suspected or confirmed preeclampsia, in order to improve the reliability of monitoring. Plasma levels of beta-2 microglobulin, cystatin C and beta trace protein are known to reflect renal filtration in non-pregn

Extracts of submerged cultures of a Stereum species afforded four new pentasubstituted phenolic compounds, named hericenols A, B, C, and D (1-4), 6-hydroxymethyl-2,2-dimethylchroman-4-one (5) and the known erinapyrone C. Hericenol A (1) showed weak antimicrobial activity while hericenol C (3) was weakly cytotoxic. The structures of the metabolites were determined by spectroscopic techniques. (C) 2

A thermomechanical model of a porous material is presented. The constitutive model is based on the Gurson model, formulated within a thermodynamic framework and adapted to large deformations. The thermodynamic framework yields a heat equation that naturally includes the mechanical dissipation. To introduce a length scale, the Gurson model was enhanced through non-local effects of the porosity bein

Popular Abstract in Swedish Denna avhandling validerar industriella mätsystem, där både de tekniska och mänskliga aspekterna innefattas. Syfte är att få bättre kunskap om den mätteknik som används för att kunna kvalitetsbestämma produkter och för att slutligen på ett mer pålitligt sätt kunna bestämma kvalitén på den tillverkande produkten. För att kunna göra detta föreslårs en metod som tar fram eAlthough there is a fairly large number of books and articles concerning the validation of technical measurement systems, there are only a few which take into account the whole measurement system consisting of both technical and non-technical aspects. A measurement system comprises both the measurement process and the human being who conducts the measurement. In this way, the human being may be a

In wastewater treatment plants (WWTPs) equipped with sludge digestion and dewatering systems, the reject water originating from these facilities contributes significantly to the nitrogen load of the activated sludge tanks, to which it is typically recycled. In this paper, the impact of reject water streams on the performance of a WWTP is assessed in a simulation study, using the Benchmark Simulati

DNA ploidy and S-phase fraction (SPF) were determined by flow cytometry on paraffin-embedded tumor material from 243 patients treated during 1980-1985. Patients with well differentiated and moderately differentiated tumors without solid areas (n = 351) formed a low-risk group (corrected 5-year survival 90%). Twenty-four patients, dead of disease within 5 years, were compared with 52 survivors. The

Abstract in UndeterminedIt has so far been difficult to identify genes behind polygenic autoimmune diseases such as rheumatoid arthritis (RA), multiple sclerosis (MS), and type I diabetes (T1D). With proper animal models, some of the complexity behind these diseases can be reduced. The use of linkage analysis and positional cloning of genes in animal models for RA resulted in the identification of

Popular Abstract in Swedish Cykeln som transportmedel har många fördelar för individ och samhälle. Det är ett mycket energisnålt transportmedel, det förorenar inte, bullrar inte, tar liten plats och ger dem som cyklar välbefinnande och motion. Om fler cyklade istället för att åka bil skulle detta medföra trevligare stadsmiljöer. Ökad cykling hade också kunnat bidra till en ökad folkhälsa. För närThis work presents an evaluation of bicycle lane effects on cyclist safety and the ability of bicycles to compete with car traffic. Thirteen Swedish urban streets were studied before and after bicycle lanes were introduced. Data was collected using video recordings, speed studies, road side questionnaires/interviews with cyclists/car drivers, conflict studies and accident analysis. Results showed

An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was possible to obtain chorionic villi free from contamination by maternal tissue. It was also possible to pick out villi (rich in blood vessels and wi