OBJECTIVE—To estimate the occurrence of early-onset renal involvement in a nationwide population-based cohort of young adults with diabetes in Sweden and relate the findings to glycemic control, type of diabetes, sex, smoking, and blood pressure. RESEARCH DESIGN AND METHODS—The Diabetes Incidence Study in Sweden aims to register all incident cases of diabetes in the age-group 15–34 years. In 1987

Investigation of an acetone extract from asafetida afforded two drimane sesquiterpene dienones (fetidones A and B, 1a,b) and several known sesquiterpene coumarin ethers, one of which (8-acetoxy-5-hydroxyumbelliprenin, 2a) showed potent and specific NF-kappa B-inhibiting properties. This, coupled to a negligible cytotoxicity, qualifies 2a as a new anti-inflammatory chemotype, and its occurrence in

Recension av Sten O. Karlsson; När industriarbetaren blev historia. Studier i svensk arbetarhistoria 1965–1995.

Background and aims: The gastric hormone ghrelin has been reported to stimulate food intake, increase weight gain, and cause obesity but its precise physiological role remains unclear. We investigated the long term effects of gastrectomy evoked ghrelin deficiency and of daily ghrelin injections on daily food intake, body weight, fat mass, lean body mass, and bone mass in mice. Methods: Ghrelin wa

The authors combine principles from software inspection, use cases, and operational profile testing to create the usage-based reading technique, in which the user reads a design document guided by prioritized use cases. UBR takes the user's viewpoint on software and the faults it might contain. Evaluation showed that the method is more effective and efficient in finding faults that are critical to

This work adds a quantitative description of distortion to the structured design method of negative-feedback amplifiers. It constitutes a power-series representation of the feedback amplifier, which may include dynamic (memory) effects, where the design parameters appear explicitly. These results have been incorporated into the systematic design method. It now includes design steps for calculating

Contains 27 chapters on defense mechanisms with authors from 10 countries, 6 of them from Lund. The coverage is comprehensive including theories of psychological defense, methods to describe defense empirically, studies of defense in various clinical groups, etc. The book can be used, in its entirety or in parts, as a text for students in clinical psychology.

OBJECTIVE: The authors sought to determine whether a series of needle acupuncture treatments produced long-term relief of chronic low back pain. DESIGN: A blinded placebo-controlled study with an independent observer. The patients were randomized to receive manual acupuncture, electroacupuncture, or active placebo (mock transcutaneous electrical nerve stimulation). Subjects were examined and monit

During a study of microfungi in Swedish coniferous forest soils (Soderstrom &Baath, 1978), a fungus was isolated which did not match any genus or species hitherto described. It is introduced here as a new species and genus.

Background. The procedure of human islet isolation needs further optimization and standardization. Here, we describe techniques to enhance enzymatic digestion and minimize mechanical forces during the digestion process. The isolation protocol has also been modified to meet current GMP (cGMP) standards. Moreover, the impact of donor- and process-related factors was correlated to the use of islets f

We study the large-time dynamics of a Markov process whose states are finite but unbounded graphs. The number of vertices is described by a supercritical branching process, and the edges follow a certain mean-field dynamics determined by the rates of appending and deleting: the older an edge is, the lesser is the probability that it is still in the graph. The lifetime of any edge is distributed ex