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Ophiostomatoid fungi synergize attraction of the Eurasian spruce bark beetle, Ips typographus to its aggregation pheromone in field traps

Eurasian spruce bark beetle, Ips typographus is a destructive pest of the Norway spruce (Picea abies). Recent outbreaks in Europe have been attributed to global warming and other anthropogenic impacts. Bark beetles are guided by multiple complex olfactory cues throughout their life cycle. Male-produced aggregation pheromones, comprising 2-methyl-3-buten-2-ol and cis-verbenol, have been identified

Quantitative myocardial perfusion during stress using CMR is impaired in healthy Middle Eastern immigrants without CV risk factors

Middle Eastern immigrants constitute a growing proportion of the European population and compared to native Swedes are more insulin resistant, which can contribute to atherosclerosis. Quantitative first pass perfusion (qFPP) using cardiovascular magnetic resonance (CMR) can detect early signs of cardiovascular disease (CVD). The aim was to study if myocardial perfusion differs between healthy male

Insight into the Mammalian Aquaporin Interactome

Aquaporins (AQPs) are a family of transmembrane water channels expressed in all living organisms. AQPs facilitate osmotically driven water flux across biological membranes and, in some cases, the movement of small molecules (such as glycerol, urea, CO2, NH3, H2O2). Protein–protein interactions play essential roles in protein regulation and function. This review provides a comprehensive overview of

Early Life Factors and Disease Development in Childhood

Kejsarsnitt, utebliven amning och antibiotika ökar risken för sjukdomar Hur många av dina vänner har någon form utav allergi? Pollen, nötter? Trots att vår sjukvård är bättre än någonsin har vi en stor ökning av sjukdomar i samhället, bland annat allergier. Varför är det så? Kliande ögon, snuva, nästäppa… Låter det bekant? Var tredje svensk har någon form utav allergi, vilka kan vara allt från lBackground and Aim The aim was to investigate the effects of four early life factors – delivery mode, feeding method, probiotics, and antibiotics – on disease development in childhood. This was done by conducting a structured literature review. Methods A literature search was performed in PubMed, Google Scholar and ReadCube Papers for studies published between January 2000 and October 2022. For e

Combinatorial gene targeting in primary human hematopoietic stem and progenitor cells

The CRISPR/Cas9 system offers enormous versatility for functional genomics but many applications have proven to be challenging in primary human cells compared to cell lines or mouse cells. Here, to establish a paradigm for multiplexed gene editing in primary human cord blood-derived hematopoietic stem and progenitor cells (HSPCs), we used co-delivery of lentiviral sgRNA vectors expressing either E

The primeval optical evolving matter by optical binding inside and outside the photon beam

Optical binding has recently gained considerable attention because it enables the light-induced assembly of many-body systems; however, this phenomenon has only been described between directly irradiated particles. Here, we demonstrate that optical binding can occur outside the focal spot of a single tightly focused laser beam. By trapping at an interface, we assemble up to three gold nanoparticle

Microstructure and wear investigation of TiC reinforced Hadfield Steel

Hadfield steel, which is a high-manganese steel alloy, is commonly used as liner for various types of rock crushers. It is used in this application due to its high toughness in combination with its high work hardening ability. Toughness is important for resisting the high impact from rocks during processing. However, the high stress gauging abrasive wear is still significant. This can lead to prod

Effect of the Cooling Rate and the Surface Film Composition on the Colloidal Stability of Whey Protein Based Emulsions of Triacylglycerols

The goal of this project was to investigate the effect and interplay of formulation and processing parameters on the colloidal stability of emulsified triacylglycerols from a product quality perspective. Different methods to quantify and monitor this effect over time were evaluated. The results of this study were intended to lead to the development of industry relevant recommendations to optimise

Engineering of Rhodosporidium toruloides for the production of value-added chemicals

There are currently increasing concerns about escalating crude oil prices, depleted petroleum resources, and environmental damages caused by plastics. In light of this, bio-based and biodegradable materials, such as polyhydroxyalkanoates (PHAs), have gained global attention from industry and academia as sustainable alternatives to petroleum-based materials. Poly-hydroxybutyrate (PHB) is the simple

Feasibility study of computational occupational dosimetry : evaluating a proof-of-concept in an endovascular and interventional cardiology setting

Individual monitoring of radiation workers is essential to ensure compliance with legal dose limits and to ensure that doses are As Low As Reasonably Achievable. However, large uncertainties still exist in personal dosimetry and there are issues with compliance and incorrect wearing of dosimeters. The objective of the PODIUM (Personal Online Dosimetry Using Computational Methods) project was to im

Transformative Adaptation in Livestock Production Systems

Climate change impacts on agricultural systems are intensifying. The recent IPCC report illustrates that as temperatures climb, changes in the climate are pushing systems beyond sustainable boundaries. This is the case with certain livestock production systems (e.g. climate impacts can result in devastated supply chains or crop failures). When climate impacts are, or are projected to be, so severe

Y2Mo3O12–Ba0.5Sr0.5Co0.8Fe0.2O3-δ cathode catalyst for proton-conducting solid oxide fuel cells

The mismatch of the coefficients of thermal expansion between cathode and electrolyte is one of the thorniest problems for high-performance proton-conducting solid oxide fuel cells (H–SOFCs). Here one strategy is applied by introducing the negative thermal expansion component, Y2Mo3O12 (YMO), on Ba0.5Sr0.5Co0.8Fe0.2O3-δ (BSCF) cathode to overcome this difficulty. As a result, not only the electrol

Bidirectional associations of intellectual and social activities with cognitive function among middle-aged and elderly adults in China

Background: Previous studies evaluating the association between leisure activities and cognitive function produced conflicting results. Different types of leisure activities may have different effects on cognition, and very few studies have explored their bidirectional associations. Our study aimed to explore whether intellectual and social activities had bidirectional associations with cognitive

Childhood neighborhoods and cause-specific adult mortality in Sweden 1939-2015

The socioeconomic health gradient has widened since the mid-21st century, but the role of childhood neighborhoods remains underexplored. Most neighborhood studies on health are cross-sectional, and longitudinal research is lacking.We analyze how socioeconomic neighborhood conditions in childhood influence cause-specific deaths in adulthood. We use uniquely detailed geocoded longitudinal microdata

Familial risk associated with lung cancer as a second primary malignancy in first-degree relatives

Background: Aggregation of lung cancer (LCa) in family members is well-documented. However, little is known on the familial risk of LCa when first-degree relatives (FDRs, parents or siblings) are diagnosed with LCa as a second primary malignancy (LCa-2). We aimed to investigate whether and to what extent a family history of LCa-2 was associated with an increased LCa risk. Methods: In this Swedish

Unaided efficient transglutaminase cross-linking of whey proteins strongly impacts the formation and structure of protein alginate particles

There is a dogma within whey protein modification, which dictates the necessity of pretreatment to enzymatic cross-linking of β-lactoglobulin (β-Lg). Here microbial transglutaminase (MTG) cross-linked whey proteins and β-Lg effectively in 50 mM NaHCO3, pH 8.5, without pretreatment. Cross-linked β-Lg spanned 18 to >240 kDa, where 6 of 9 glutamines reacted with 8 of 15 lysines. The initial isopeptid

Strain Rate Characterization of Packaging Materials

This master thesis firstly introduced the basic knowledge of packaging materials through a literature survey focused on exploring the effect of strain-rate on mechanical properties of paperboard materials. By means of tensile tests and microscopic observation, the changes of mechanical properties such as yield strength, strain and Young's modulus of the two different paperboards used in lamina

The mental work environment and social work environment on the senior workforce

Introduction: The Swedish Agency for Work Environment Expertise commissioned researchers atLund University, Kristianstad University and Malmö University to conduct a systematic reviewfocusing on the impact of the psychosocial work environment on the senior workforce (≥55 years ofage) in a Swedish context.Aims: To provide an overview of how psychosocial work environment and occupational healthfacto