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To acquire a better understanding of clonal evolution of acute myeloid leukemia (AML) and to identify the clone(s) responsible for disease recurrence, we have comparatively studied leukemia-specific mutations by whole-exome-sequencing (WES) of both the leukemia and the nonleukemia compartments derived from the bone marrow of AML patients. The T-lymphocytes, B-lymphocytes and the functionally norma

The industrial relations models among the EU/EES countries vary widely. The Nordic model of self-regulation contrasts sharply to French state extension of collective agreements and minimum wage set by the state. While social dialogue often refers to tripartite negotiations, bipartite collective bargaining is characteristic of self-regulation. Swedish self-regulation is the most far-reaching among

We postulate that exit from pluripotency involves intermediates that retain pluripotency while simultaneously exhibiting lineage-bias. Using a MIXL1 reporter, we explore mesoderm lineage-bias within the human pluripotent stem cell compartment. We identify a substate, which at the single cell level coexpresses pluripotent and mesodermal gene expression programmes. Functionally these cells initiate

Considering the current resources scarcity, Wastewater Treatment Plants (WWTP) should be adapted to become more sustainable. For example, it is possible to recover resources present in municipal wastewater. However, regional studies about integration of resource recovery processes at different scales or about the main barriers to implementation in developing countries are missing in the literature

PREVENTIVE VACCINATION IS SUCCESSFULLY PRACTISED TODAY AGAINST TWO NEOPLASTIC DISEASES OF DOMESTIC ANIMALS: fibropapillomatosis of cattle and Marek's disease of chickens (a lymphoproliferative disease). Also it may soon be possible to immunize cats against lymphosarcoma. This memorandum describes these diseases and the immunological reactions involved. It also mentions a number of other tumours th

Part 1 of this Memorandum appeared in Vol. 49, pages 81-91. Part 2 covers neoplasia of the bovine urinary bladder; tumours of unknown cause (including melanomas, osteosarcomas, mammary tumours, lymphosarcomas, mastocytomas, transmissible venereal tumours, and histiocytomas); and the applications of animal models in studies of neoplasia. A summary of animal models is included as an annex.

Arkeologerna, Statens historiska museer i Lund, har den 10–11 september 2020, på uppdrag av Länsstyrelsen i Skåne län, utfört en arkeologisk efterundersökning av en fyndplats för stenhällar inom fastigheten Mellby 3:52, Södra Mellby socken, Simrishamns kommun.Efterundersökningen föranleddes av att det i samband med grävning för en grindstolpe invid bronsåldersröset Bredarör (Kiviksgraven), i april

Arkeologerna, Statens historiska museer i Lund har den 7–8 september 2020, på uppdrag av Länsstyrelsen Skåne, utfört en arkeologisk efterundersökning av en skelettgrav inom fastigheten Kiaby 21:8 och inom fornlämning L1990:564/Kiaby 81:1, Kiaby socken, nordöstra Skåne.Efterundersökningen föranleddes av att det i samband med trädgårdsarbete 2017 påträffats skelettdelar av människa i en planteringsg

This review highlights the importance of air quality in the African urban development process. We address connections between air pollution and (a) rapid urbanization, (b) social problems, (c) health impacts, (d) climate change, (e) policies, and ( f ) new innovations. We acknowledge that air pollution levels in Africa can be extremely high and a serious health threat. The toxic content of the pol