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The growing season greenhouse gas balance of a continental tundra site in the Indigirka lowlands, NE Siberia
Carbon dioxide and methane fluxes were measured at a tundra site near Chokurdakh, in the lowlands of the Indigirka river in north-east Siberia. This site is one of the few stations on Russian tundra and it is different from most other tundra flux stations in its continentality. A suite of methods was applied to determine the fluxes of NEE, GPP, R-eco and methane, including eddy covariance, chamber
Gender differences in species recognition and the evolution of asymmetric sexual isolation
Closely related sympatric species are expected to evolve strong species discrimination because of the reinforcement of mate preferences [1-4]. Fitness costs of heterospecific matings are thought to be higher in females than in males, and females are therefore expected to show stronger species discrimination than males [5, 6]. Here, we investigated gender and species differences in sexual isolation
The protein catalysing the conversion of D-dopachrome to 5,6-dihydroxyindole is a phenylpyruvate tautomerase (EC 5.3.2.1)
Scanning photoelectron microscopy study of as-grown and heat-treated chemical vapor deposition boron-doped diamond films
The electronic structure of as-grown and high temperature (1625 C) annealed chemical vapour deposition boron-doped (1-4 ppm) diamond films has been studied using a scanning photoelectron microscope with lateral resolution in the 1 mum range. The fresh surfaces have been obtained by cleaving free-standing films in situ at a pressure of 7 X 10(-11) Torr. The major part of the contrast in photoelectr
Postprandial interstitial insulin concentrations in type 2 diabetes relatives
Backround An endothelial barrier for the insulin transport from the circulation to the target tissues of insulin has previously been suggested to contribute to insulin resistance. The interstitial insulin concentration (I-insulin) and insulin kinetics following a mixed meal have, however, previously not been characterized in human adipose tissue. Subjects and methods Eight nondiabetic first-degree
Trends in smoking behaviour between 1985 and 2000 in nine European countries by education
Objective: To examine whether trends in smoking behaviour in Western Europe between 1985 and 2000 differed by education group. Design: Data of smoking behaviour and education level were obtained from national cross sectional surveys conducted between 1985 and 2000 (a period characterised by intense tobacco control policies) and analysed for countries combined and each country separately. Annual tr
Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein
Epithelial cells of many mucosal organs have adapted to coexist with microbes and microbial products. In general, most studies suggest that epithelial cells benefit from interactions with commensal microorganisms present at the lumenal surface. However, potentially injurious molecules found in this microenvironment also have the capacity to elicit local inflammatory responses and even systemic dis
Familial presenile dementia with bitemporal atrophy.
Effects of litter size on pup defence and weaning success of neighbouring bank vole females
Reproductive success of territorial female mammals depends partly on their capability to defend their young from conspecific intruders. However, how this is related to the characteristics of females and their litter sizes is largely unknown. The defence activity of 25 female bank voles (Clethrionomys glareolus) in relation to the number of offspring was studied in a behavioural arena by manipulati
Scaling properties of azimuthal anisotropy in Au plus Au and Cu plus Cu collisions at root s(NN)=200 GeV
Differential measurements of elliptic flow (v(2)) for Au+Au and Cu+Cu collisions at root s(NN)=200 GeV are used to test and validate predictions from perfect fluid hydrodynamics for scaling of v(2) with eccentricity, system size, and transverse kinetic energy (KET). For KET equivalent to m(T)-m up to similar to 1 GeV the scaling is compatible with hydrodynamic expansion of a thermalized fluid. For
myo-Inositol monophosphatase is an activated target of calbindin D28k.
Calbindin D28k (calbindin) is a member of the calmodulin superfamily of Ca2+ -binding proteins. An intracellular target of calbindin was discovered using bacteriophage display. Human recombinant calbindin was immobilized on magnetic beads and used in affinity purification of phage-displayed peptides from a random 12-mer peptide library. One sequence, SYSSIAKYPSHS, was strongly selected both in the
New release cell for NMR microimaging of tablets Swelling and erosion of poly(ethylene oxide)
A small release cell, in the form of a rotating disc, has been constructed to fit into the MRI equipment. The present work show that both qualitative and quantitative information of the swelling and erosion behavior of hydrophilic extended release (ER) matrix tablets may be obtained using this release cell and non-invasive magnetic resonance imaging (MRI) studies at different time-points during ma
Reumacon (CPH82) showed similar x-ray progression and clinical effects as methotrexate in a two year comparative study on patients with early rheumatoid arthritis
Objectives. To study x-ray development and clinical effects, tolerability and safety after 2 years treatment of RA patients with Reumacon (CPH82) or methotrexate (MTX). Patients and methods. This study is a 74 week open continuation of a 24 week double blind comparison of 100 patients with early RA (disease duration less than 2 years) treated either with Reumacon or MTX. Results. The mean Larsen s
Automatic measurement of atrial pacing thresholds in dual-chamber pacemakers: Clinical experience with atrial capture management
BACKGROUND The Medtronic EnPulse (TM) pacemaker incorporates the new atrial capture management (ACM) algorithm to automatically measure atrial capture thresholds and subsequently manage atrial pacing outputs. OBJECTIVES The purpose of this study was to evaluate the clinical performance of ACM. METHODS Two hundred patients with an indication for a dual-chamber pacemaker underwent implantation. ACM
Quantum path distributions for high-order harmonics in rare gas atoms
We present quantum path distributions of high-order harmonics produced by rare gas atoms interacting with an intense 810 nm laser field, obtained by numerical integration of the time-dependent Schrodinger equation within the single active electron approximation. We find that the distributions are sensitive to the atomic potentials, and differ from the distributions predicted by the strong field ap
Low level of gene transfer to and engraftment of murine bone marrow cells from long-term bone marrow cultures
OBJECTIVE: We wanted to determine whether the long-term bone marrow culture (LTBMC) transduction system would lead to efficient gene transfer and engraftment of murine repopulating hematopoietic stem cells (HSC), particularly in nonablated recipients. MATERIALS AND METHODS: Congenic mouse strains expressing Ly 5.1 or Ly 5.2 and the GP+E86 cell line producing the MGirL22Y vector carrying the gene f
The relationship between natural variation in chiasma frequencies and recombination frequencies in barley.
A combined quantum and molecular mechanical study of the O-2 reductive cleavage in the catalytic cycle of multicopper oxidases
The four-electron reduction of dioxygen to water in multicopper oxidases takes place in a trinuclear copper cluster, which is linked to a mononuclear blue copper site, where the substrates are oxidized. Recently, several intermediates in the catalytic cycle have been spectroscopically characterized, and two possible structural models have been suggested for both the peroxy and native intermediates
Paleoecology of the Early Permian strata at heimefrontfjella, Dronning Maud Land, Antarctica
Palaeopalynological studies form an integral part of the geological investigation of the Late Paleozoic sedimentary history of Dronning Maud Land. During the examination of organic residues prepared from different localities at Heimefrontfjella, the freshwater green alga Botryococcus was found. Exceptionally well-preserved colonies of Botryococcus were recorded in several samples at two sections o