CRISPR/Cas9 induced overexpression of GABA receptor α1-subunit and CB1 receptor
Epilepsy is one of the most common neurological diseases that affects 1 % of the human population. After an initial insult, the brain undergoes several changes that lead to hyperexcitability. These changes include downregulation of both GABAA receptor subunits and CB1 receptors. These receptors normally work to decrease excitability, so their downregulation leads to an increase in excitability. If
