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PurposeIn early breast cancer (BC), five conventional biomarkers—estrogen receptor (ER), progesterone receptor (PgR), human epidermal growth factor receptor 2 (HER2), Ki67, and Nottingham histologic grade (NHG)—are used to determine prognosis and treatment. We aimed to develop classifiers for these biomarkers that were based on tumor mRNA sequencing (RNA-seq), compare classification performance, a

Invariant differential yields of deuterons and antideuterons in pp collisions at s = 0.9, 2.76 and 7 TeV and the yields of tritons, He3 nuclei, and their antinuclei at s = 7 TeV have been measured with the ALICE detector at the CERN Large Hadron Collider. The measurements cover a wide transverse momentum (pT) range in the rapidity interval |y|

Background: Short-culm mutants have been widely used in breeding programs to increase lodging resistance. In barley (Hordeum vulgare L.), several hundreds of short-culm mutants have been isolated over the years. The objective of thepresent study was to identify the Brachytic1 (Brh1) semi-dwarfing gene and to test its effect on yield and malting quality.Results: Double-haploid lines generated throu

The differential cross-section for the production of a W boson in association with a top quark is measured for several particle-level observables. The measurements are performed using 36.1fb-1 of pp collision data collected with the ATLAS detector at the LHC in 2015 and 2016. Differential cross-sections are measured in a fiducial phase space defined by the presence of two charged leptons and exact

High-spin states in Cs124 were populated in the Ni64(Ni64,p3n) reaction and the Gammasphere detector array was used to measure γ-ray coincidences. Both positive- and negative-parity bands, including bands with chiral configurations, have been extended to higher spin, where a shape change has been observed. The configurations of the bands before and after the alignment are discussed within the fram

Submerged macrophytes play a key role in north temperate shallow lakes by stabilizing clear-water conditions. Eutrophication has resulted in macrophyte loss and shifts to turbid conditions in many lakes. Considerable efforts have been devoted to shallow lake restoration in many countries, but long-term success depends on a stable recovery of submerged macrophytes. However, recovery patterns vary w

This article focuses on how the European Union's (EU) mediation activities during the Russia-Ukraine and Israel-Palestine conflicts are perceived by local elites. Our analysis is based on recent interviews with decision makers in Ukraine, Israel and Palestine. Consistent with this special issue, we investigate perceptions of EU roles, strategies and effectiveness. We suggest that the EU's relation

The outcome of the British Brexit referendum sent shockwaves across Europe. It sent signals about the future of the European Union (EU), not only to the Member States but also to the surrounding world. How to characterize the EU after Brexit? We address this problematic by investigating the metaphors applied to the EU in the Russian and Ukrainian press in the first week after the referendum. We fi

We present the generalized signal detection theory (GSDT), where familiarity is described by a sparse binomial distribution of binary node activity rather than by normal distribution of familiarity. Items are presented in a distributed representation, where each node receives either noise only, or signal and noise. An old response (i.e., a ‘yes’ response) is made if at least one node receives sign

Journal of Thrombosis and Haemostasis DOI: 10.1111/j.1538-7836.2011.04380

En populär-teologisk bearbetning av frågor som rör frälsning, försoning, tro, dop och pånyttfödelse ur ett klassiskt pentekostalt/baptistiskt perspektiv och med särskilt fokus på barn och barn-teologi.

The global cobalt cycle in society was modelled using an integrated systems dynamics model, WORLD6, integrating several earlier system dynamics models developed by the authors. The COBALT sub-model was used to assess the long-term sufficiency of the available extractable cobalt and address the effect of different degrees of recycling on cobalt supply. The extraction of cobalt is mostly dependent o

A model for global supply of sand, gravel and cut stone for construction based on a system dynamics model was developed for inclusion in the WORLD6 model. The Sand-Gravel-Stone model simulates production and market supply, demand and price for natural sand and gravel, sand and gravel from crushed rock and cut stone. The model uses market mechanisms where the demand is depending on population size,

We have built a system dynamics model, WORLD6, that takes into account population, energy extraction, production and need, aspects social behaviour, material and metals recycling and important links to the economy. The model is ground-truthed by comparing with actual supply per person from 1900 till 2015 and run until 2400. Primary scarcity metrics are supply per person and year and stock-in-use p