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Does microbiological contamination of homografts prior to decontamination affect the outcome after right ventricular outflow tract reconstruction?

OBJECTIVES: Homografts are often in short supply. Today, European guidelines recommend that all tissues contaminated by any of 18 different bacteria and fungi be discarded before antibiotic decontamination has been conducted. The tissue bank in Lund uses more liberal protocols: It accepts all microbes prior to decontamination except multiresistant microbes and Pseudomonas species. The aim of this

Habitat geometry in artificial microstructure affects bacterial and fungal growth, interactions, and substrate degradation

Microhabitat conditions determine the magnitude and speed of microbial processes but have been challenging to investigate. In this study we used microfluidic devices to determine the effect of the spatial distortion of a pore space on fungal and bacterial growth, interactions, and substrate degradation. The devices contained channels differing in bending angles and order. Sharper angles reduced fu

Vocal signals only impact speakers’ own emotions when they are self-attributed

Emotions are often accompanied by vocalizations whose acoustic features provide information about the physiological state of the speaker. Here, we ask if perceiving these affective signals in one's own voice has an impact on one's own emotional state, and if it is necessary to identify these signals as self-originated for the emotional effect to occur. Participants had to deliberate out loud about

Knowledge management support of engineering change management and adaptive design in serial and one-of-a-kind production

Knowledge management has strategic importance for any manufacturing enterprise. Systematically gathered, analyzed, and interpreted professional experiences can prevent technical problems, unnecessary costs, and unnecessary engineering changes. The model for recording of knowledge and its integration into the engineering change and adaptive design processes is the main contribution of this publicat

A short-term comparison of expander prosthesis and DIEP flap in breast reconstructions : A prospective randomized study

Background: There is yet no clear consensus on which method is preferable in secondary breast reconstructions, prosthesis, or autologous tissue. Methods: In this first prospective randomized study, 29 women underwent reconstruction with expander prosthesis (EP) and 44 with deep inferior epigastric perforator (DIEP) flap. Inclusion started in 2012 and ended in 2018. Demographic data, complications,

Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application : a prospective, observational study

Background: As many countries seek to slow the spread of COVID-19 without reimposing national restrictions, it has become important to track the disease at a local level to identify areas in need of targeted intervention. Methods: In this prospective, observational study, we did modelling using longitudinal, self-reported data from users of the COVID Symptom Study app in England between March 24,

Study of the scattering of 15C at energies around the Coulomb barrier

The neutron rich carbon isotope 15C is the only known case of an almost "pure"2s1/2 single-neutron halo ground state configuration. At collision energies around the Coulomb barrier the reaction dynamics is expected to be dominated by single neutron transfer and breakup. To investigate these effects, we have measured the scattering of 15C with a 208Pb target at 65 MeV at the HIE-ISOLDE facility in

Article 17 DSM Directive: the Swedish proposal (Part 2)

Commentary and analysis of the proposal of the Swedish Ministry of Justice (Ds 2021:30) concerning implementation of Article 17 Directive 2019/790 on copyright and related rights in the Digital Single Market (DSM Directive). Part 2 of 2.

Cultural ideals in the entrepreneurship industry

As both public and private organizations are spending resources on fostering entrepreneurship, we have witnessed the emergence of an entrepreneurship industry. Using the entrepreneurship industry in Sweden as a case and example, this chapter provides an explorative analysis the emergence, manifestations and consequences of cultural ideals within this industry. The analysis reveals how the entrepre

Collection and Reporting of Patient-reported Outcome Measures in Arthroplasty Registries: Multinational Survey and Recommendations

BACKGROUND: Patient-reported outcome measures (PROMs) are validated questionnaires that are completed by patients. Arthroplasty registries vary in PROM collection and use. Current information about registry collection and use of PROMs is important to help improve methods of PROM data analysis, reporting, comparison, and use toward improving clinical practice. QUESTIONS/PURPOSES: To characterize PR

Seasonal variations in use and outcome of rapid antigen detection tests and cultures in pharyngotonsillitis : a register study in primary care

Background: Diagnosis and treatment of pharyngotonsillitis are commonly focused on group A streptococci (GAS), although the disease is often associated with other pathogens. While the incidence of pharyngotonsillitis is known to vary with season, seasonal variations in the prevalence of potential pathogens are sparsely explored. The aim of this study was to explore any seasonal variations in the u

Neurocognitive function following out-of-hospital cardiac arrest : A systematic review

Objectives: The primary aim of this review was to investigate neurocognitive outcomes following out-of-hospital cardiac arrest (OHCA). Specifically, the focus was on identifying the different neurocognitive domains that are assessed, the measures used, and the level of, and criteria for, impairment. Design and review methods: A systematic review of the literature from 2006 to 2021 was completed us

Bird population declines and species turnover are changing the acoustic properties of spring soundscapes

Natural sounds, and bird song in particular, play a key role in building and maintaining our connection with nature, but widespread declines in bird populations mean that the acoustic properties of natural soundscapes may be changing. Using data-driven reconstructions of soundscapes in lieu of historical recordings, here we quantify changes in soundscape characteristics at more than 200,000 sites

Large-scale variations in the dynamics of Amazon forest canopy gaps from airborne lidar data and opportunities for tree mortality estimates

We report large-scale estimates of Amazonian gap dynamics using a novel approach with large datasets of airborne light detection and ranging (lidar), including five multi-temporal and 610 single-date lidar datasets. Specifically, we (1) compared the fixed height and relative height methods for gap delineation and established a relationship between static and dynamic gaps (newly created gaps); (2)

Suppression of unpolarized background interferences for Raman spectroscopy under continuous operation

A time-resolving filtering technique developed to improve background suppression in Raman spectroscopy is presented and characterized. The technique enables separation of signal contributions via their polarization dependency by the addition of a waveplate to a normal measurement system and data post-processing. As a result, background interferences of broadband laser-induced fluorescence and inca

Core-Level Binding Energy Reveals Hydrogen Bonding Configurations of Water Adsorbed on TiO2 (110) Surface

Using x-ray photoelectron spectroscopy of the oxygen 1s core level, the ratio between intact (D2O) and dissociated (OD) water in the hydrated stoichiometric TiO2(110) surface is determined at varying coverage and temperature. In the submonolayer regime, both the D2O:OD ratio and the core-level binding energy of D2O (ΔBE) decrease with temperature. The observed variations in ΔBE are shown with dens

Cost-effectiveness of romosozumab for the treatment of postmenopausal women with severe osteoporosis at high risk of fracture in Sweden

Summary: Romosozumab is a novel bone-building drug that reduces fracture risk. This health economic analysis indicates that sequential romosozumab-to-alendronate can be a cost-effective treatment option for postmenopausal women with severe osteoporosis at high risk of fracture. Purpose: To estimate the cost-effectiveness of sequential treatment with romosozumab followed by alendronate (“romosozuma

The complexity of wood ash fertilization disentangled : Effects on soil pH, nutrient status, plant growth and cadmium accumulation

Wood ash is a by-product from energy production that can be recycled to forests to regain nutrients and prevent acidification. However, low concentrations of nitrogen (N) in wood ash may reduce its potential positive effect on plant growth. In addition, wood ash can have a high content of toxic heavy metals such as Cd, thus there are concerns that it may increase Cd accumulation in plants. We grew

Radiologisk och histologisk bild för en ökad förståelse vid covid-19

We here describe the current knowledge about the radiologic and histologic pulmonary features of covid-19, caused by SARS-CoV-2, and present lung histology from a case with fatal disease. Initial findings on computed tomography (CT) typically include peripheral multifocal bilateral ground-glass opacities, and correspondingly microscopic alveolar edema. This is followed by peripheral consolidations