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Toxicity of stainless and mild steel particles generated from gas–metal arc welding in primary human small airway epithelial cells

Welding fumes induce lung toxicity and are carcinogenic to humans but the molecular mechanisms have yet to be clarified. The aim of this study was to evaluate the toxicity of stainless and mild steel particles generated via gas–metal arc welding using primary human small airway epithelial cells (hSAEC) and ToxTracker reporter murine stem cells, which track activation of six cancer-related pathways

Building sustainable peace: transforming environmental peacebuilding in times of climate change

The Sustainable Development Goals outline a “shared blueprint for peace and prosperity for people and the planet, now and into the future”. However, this is not only ambitious; there appear to be inherent contradictions to reconciling the economic, environmental, and social goals. Goal 16 on Peace, Justice and Strong Institutions relies on the promotion of “sustainable development” to achieve envi

The Emergence, Establishment och Expansion of Fear of Crime Research in Sweden

Vad hände med innebörden av ordet "otrygghet", ett ord med gamla svenska rötter och en tidigare etablerad innebörd, när det amerikanska forskningsfältet "Fear of Crime" introducerade i Sverige och översattes till "Otrygghet"? Syftet med denna avhandling är att beskriva trygghetsforskningens uppkomst, etablering och expansion i Sverige, i syfte att besvara frågor om forskningsdiskursens funktion, sThe purpose of this dissertation is to construct an historical account of the emergence, establishment, and expansion of fear of crime research in Sweden. This dissertation aims to answer questions about the function, spread, and high level of institutional engagement of fear of crime research by analyzing the literature and examining the methodological, theoretical, and epistemological origins of

Tragedy of the facilitated commons: A multiple case study of failure in systematic horizontal logistics collaboration

Horizontal logistics collaboration can increase environmental sustainability and reduce shipping costs. Given these benefits—and the fact that few shippers actually opt to collaborate—public sector agencies and industry associations have attempted to sponsor and support the facilitation of horizontal logistics collaboration projects over the past 20 years. The literature, however, has yet to revea

Functional Antibodies Against SARS-CoV-2 Receptor Binding Domain Variants with Mutations N501Y or E484K in Human Milk from COVID-19-Vaccinated, -Recovered, and -Unvaccinated Women

Background: New variants are evolving in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and receptor binding domain (RBD) mutations have been associated with a higher capacity to evade neutralizing antibodies (NAbs). We aimed at determining the impact of COVID-19 vaccine and infection on human milk antibody titers and activity against the RBD mutations from SARS-CoV-2 variants of co

Plasma circulating cell-free mitochondrial DNA in depressive disorders

Plasma circulating cell-free mitochondrial DNA (ccf-mtDNA) is an immunogenic molecule and a novel biomarker of psychiatric disorders. Some previous studies reported increased levels of ccf-mtDNA in unmedicated depression and recent suicide attempters, while other studies found unchanged or decreased ccf-mtDNA levels in depression. Inconsistent findings across studies may be explained by small samp

Process for the preparation of a dendritic polyol

A process for synthesis of a polymeric polyalcohol substantially and preferably built up form polyester units and composed of a monomeric or polymeric initiator molecule to which at least one dentritic branch (dendron) consisting of a number of branching generations is added. The branching generations comprise a polymericor monomeric branching chain extender having three reactive functions of whic

Snapshot multicolor fluorescence imaging using double multiplexing of excitation and emission on a single detector

Fluorescence-based multispectral imaging of rapidly moving or dynamic samples requires both fast two-dimensional data acquisition as well as sufficient spectral sensitivity for species separation. As the number of fluorophores in the experiment increases, meeting both these requirements becomes technically challenging. Although several solutions for fast imaging of multiple fluorophores exist, the

Hypoxemia severity and survival in ILD and COPD on long-term oxygen therapy – The population-based DISCOVERY study

Background and aim: Whether long-term oxygen therapy (LTOT) improves survival in interstitial lung disease (ILD) is unclear. A recent study reported similar survival in ILD patients with severe hypoxemia on LTOT vs. moderate hypoxemia without LTOT, and proposed that LTOT could be indicated in ILD already at moderate hypoxemia. The aim of this study was to compare survival by severity of hypoxemia

Synthesis and Cationic Photopolymerization of New Silicon-Containing Oxetane Monomers

The cationic photopolymerization of oxetane-based systems containing silicon monomers was investigated. For this purpose, three new silicon-containing oxetane monomers were synthesized through a simple and straightforward synthetic method. The silicon-containing monomers were added to a typical oxetane resin, 3,3-[oxydi(methylene)]bis(3-ethyloxetane), in concentrations of 1-5 wt %. They exploited

Matching N3LO QCD calculations to parton showers

The search for new interactions and particles in high-energy collider physics relies on precise background predictions. This has led to many advances in combining precise fixed-order cross-section calculations with detailed event generator simulations. In recent years, fixed-order qcd calculations of inclusive cross sections at n3lo precision have emerged, followed by an impressive progress at pro

Development of an instant-mix probiotic beverage based on fermented quinoa with reduced phytate content

Quinoa (Chenopodium Quinoa Willd.), a South American grain, has great potential for innovation and development of improved food products because of its protein content and nutritional benefits. The study aimed to develop an instant-mix beverage based on fermented quinoa with reduced phytate content and viable lactic bacteria. Two different lactic fermentation processes were designed known as Ferme

Household salt (NaCl) for optically stimulated luminescence dosimetry: an overview

This brief overview of the use of household salt (NaCl) in optically stimulated luminescence (OSL) dosimetry is focusing on the use of NaCl pellets. It is suggested that the most optimal use of household NaCl, in general prospective dosimetry, is to compress the salt grains to pellets and read the radiation induced signal using OSL rather than TL. A summary of the main OSL dosimetric properties is

The Effect of Botulinum Toxin Type A Injections on Stricture Formation, Leakage Rates, Esophageal Elongation, and Anastomotic Healing Following Primary Anastomosis in a Long- and Short-Gap Esophageal Atresia Model : A Protocol for a Randomized, Controlled, Blinded Trial in Pigs

Background:Esophageal atresia (EA) is a congenital malformation affecting 1:3000-4500 newborns. Approximately 15% have a long-gap EA (LGEA), in which case a primary anastomosis is often impossible to achieve. To create continuity of the esophagus patients instead have to undergo lengthening procedures or organ interpositions; methods associated with high morbidity and poor functional outcomes. Eso

Factors associated with unawareness of HIV-positive status in urban Ethiopia : Evidence from the Ethiopia population-based HIV impact assessment 2017-2018

BACKGROUND: The HIV epidemic in Ethiopia is concentrated in urban areas. Ethiopia conducted a Population-based HIV Impact Assessment (EPHIA) in urban areas between October 2017 and April 2018 to measure the status of the country's response to the epidemic.METHODS: We conducted field data collection and HIV testing in randomly selected households using the national, rapid testing algorithm with lab

Hyperbranched Polymers in Cationic Photopolymerization of Epoxy Systems

Mixtures of epoxy resins in the presence of epoxy hyperbranched polymers (HBP), in the range of 5-15 wt%, were investigated in the cationic photocuring process. No significant differences in rate of polymerization or final epoxy groups conversion were observed. At low concentration, HBP acts as plasticizer and causes a decrease of the glass transition temperature of the epoxy matrix and of the E'

A formaldehyde and formate reduced polyol process

Formaldehyde and formate reduced process for preparation of a di, tri or polyalcohol from formaldehyde and a second aldehyde in the presence of an alkaline catalyst. The process comprises an aldol condensation yielding a methylolaldehyde and a subsequent crossed Cannizzaro reaction yielding said di, tri or polyalcohol and formate. The Cannizzaro reaction comprises reacting said methylolaldehyde wi