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Long-term effects on function, health-related quality of life and work ability after structured physiotherapy including a workplace intervention. : A secondary analysis of a randomised controlled trial (WorkUp) in primary care for patients with neck and/or back pain

Objective: To study the long-term effects of a workplace intervention in addition to structured physiotherapy regarding self-reported measures in patients with acute/subacute neck and/or back pain. Design: WorkUp – a cluster-randomised controlled trial in 32 primary care centers in Sweden, from January 2013 through December 2014 (ClinicalTrials.gov ID: NCT02609750). Intervention: Structured physio

Malvas mystiska flaskpost

Skönlitterär bok för åldern 9-12 år.Vad är egentligen mod? Kan man lära sig att bli modig? Det frågar sig Malva, elva år, när hon inte lyckas stå inför hela klassen i skolan och berätta om sitt sommarlov. Inte ett vettigt ord får hon fram. De andra barnen fnissar och fröken suckar. En trasig flaskpost blir Malvas räddning. Genom det mystiska receptet i flaskan blir hon mindre än en tumme. Och sugs

Cerebro-spinal fluid biomarker levels : phosphorylated tau (T) and total tau (N) as markers for rate of progression in Alzheimer's disease

BACKGROUND: We investigated the potential associations between cerebro-spinal fluid (CSF) levels of phosphorylated tau (P-tau) and total tau (T-tau) with short-term response to cholinesterase inhibitor (ChEI) treatment, longitudinal outcome and progression rates in Alzheimer's disease (AD). METHODS: This prospective, observational study included 129 participants clinically diagnosed with mild-to-m

OGRDB : a reference database of inferred immune receptor genes

High-throughput sequencing of the adaptive immune receptor repertoire (AIRR-seq) is providing unprecedented insights into the immune response to disease and into the development of immune disorders. The accurate interpretation of AIRR-seq data depends on the existence of comprehensive germline gene reference sets. Current sets are known to be incomplete and unrepresentative of the degree of polymo

Scientific publications as boundary objects: theorising the intersection of classification and research evaluation

Introduction. When using bibliometrics for research evaluation, the classification of research fields is an issue of great importance. The purpose of this paper is to outline a brief theoretical framework for analysing the role of classification in research evaluation practices.Theory. Taking departure in the concept of ‘boundary objects’ we develop a theoretical framework for analyses of how scie

Construction of an ultrasound phantom with micrometer-sized wall-less vessels

The development of new ultrasound imaging technologies that aim to resolve objects smaller than the conventional ultrasounds diffraction limit calls for new types of phantoms to evaluate these technologies. When it comes to vascular flow phantoms, this becomes challenging due to the difficulty of manufacturing phantoms with vessels smaller than 1 mm in diameter. Here we describe a novel manufactur

A Process for Improved Decision-Support based on Probabilistic Methods for Risk Analysis and Building Energy Performance

This paper presents a preliminary method developed for improved decision-support based on probabilistic methods for risk assessment using building performance simulations. The aim of the method is to support the decision-maker in all stages of the building process when deciding on the design of a building by including uncertainties and quantifying; the probability of fulfilling objectives; energy

Possibilities with Probabilistic Methods for Dynamic Building Energy Simulations using Stochastic Input Data : – Initial Analysis

As observed in earlier studies, there is evidently a performance gap between the predicted annual energy use from building performance simulations basedon traditional deterministic methods compared to the monitored annual energy use of a building. The hypothesis is that using a probabilistic method makes it possible to consider the uncertainties in the input data and quantify the overall uncertainAs observed in earlier studies, there is evidently a performance gap between the predicted annual energy use from building performance simulations based on traditional deterministic methods compared to the monitored annual energy use of a building. The hypothesis is that using a probabilistic method makes it possible to consider the uncertainties in the input data and quantify the overall uncertai

Future application of probabilistic methods for building performance simulations

Many countries strive for continued reductions in energy demand from new buildings as a way of mitigating the impact of climate change. Consequently, the importance of accurate and efficient building performance simulations (BPS) increases to improve the prediction in energy demand during the design-process for buildings. As observed in earlier studies, there is currently a performance gap between

Contrast-enhanced magnetomotive ultrasound imaging (CE-MMUS) for colorectal cancer staging : Assessment of sensitivity and resolution to detect alterations in tissue stiffness

A key challenge in the treatment of colorectal cancer is identification of the sentinel draining lymph node. Magnetomotive ultrasound, MMUS, has identified lymph nodes in rat models: superparamagnetic iron oxide nanoparticles (SPIONs) accumulated in the lymph are forced to oscillate by an external magnetic field; the resulting axial displacement is recovered allowing structure delineation with pot

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle underpowered complex datasets to provide new insights into the potential function of germline variants in breast cancer prognosis. This network-based analysis studies ~7.3 million variants in 84,457 breast cancer patients in relation to breast cance