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High resolution C1s and S2p photoelectron spectra of thiophene

Using high-resolution synchrotron-radiation-based electron spectroscopy, vibrationally resolved C1s and S2p photoelectron spectra were obtained for the thiophene molecule in the gas phase. The vibrational structures were analyzed in terms of normal modes, and lifetimes were determined for the hole states. This complete analysis enabled to determine the binding energies of the chemically shifted ca

Internal and external perceptions of small state security: the case of Estonia

This article concerns small state security from a cognitive perspective and investigates Estonia as a security actor as perceived by all littoral Baltic Sea states. Drawing on unique elite survey and interview data, the article unpacks similarities and differences among internal (Estonian) and external perceptions of security, threats, and capabilities. The investigation is theoretically informed

Opportunities and Challenges of a Small State Presidency: The Estonian Council Presidency 2017

This article discusses some of the opportunities and challenges that the Estonian Council Presidency is facing during its first term in 2017. We also explore how Estonia is likely to appreach this position. The Council presidency provides a position to propagate national interests and an opportunity for leadership within the Council but can also be preceived as a silencer of domestic narrative. We

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OBJECTIVE: To test a simplified blood pressure device called Rastreometro that could be used by the Health Agents.METHODS: The Rastreometro has been developed from an ordinary aneroid sphygmomanometer, in which the numeric display is covered by an adhesive with a red zone, indicating pressures equal or above 140 mmHg and a yellow zone indicating pressures below 140 mmHg. The onset of oscillations

Social trust and sharing economy size : country level evidence from home sharing services

The sharing economy (peer-to-peer based sharing or renting activities coordinated through community-based online services) is often said to be closely related to trust. This paper examines the association empirically. Using data collected from the two sharing economy companies Airbnb and Flipkey that exist in over 100 countries, we construct a measure of sharing economy penetration and examine its

Riksbankens experiment har stått oss dyrt

Minusräntan har förvärrat de finansiella obalanserna, sänkt värdet på den svenska kronan och bidragit till ökade förmögenhetsklyftor. Det skriver nationalekonomerna Fredrik N G Andersson och Lars Jonung.

Targeting the hydrophilic regions of recombinant proteins by MS via in-solution buffer-free trypsin digestion

A desalting step using reversed phase chromatography is a common practice prior to mass spectrometry analysis of proteolytic digests in spite of the detrimental exclusion of the hydrophilic peptides. The detection of such peptides is also important for the complete coverage of protein sequences and the analysis of posttranslational modifications as inquired by regulatory agencies for the commercia

Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets

Type 2 diabetes (T2D) is characterized by insufficient insulin secretion and elevated glucose levels, often in combination with high levels of circulating fatty acids. Long-term exposure to high levels of glucose or fatty acids impair insulin secretion in pancreatic islets, which could partly be due to epigenetic alterations. We studied the effects of high concentrations of glucose and palmitate c

Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease

A hallmark of polycystic kidney diseases (PKDs) is aberrant proliferation, which leads to the formation and growth of renal cysts. Proliferation is mediated by cyclin-dependent kinases (Cdks), and the administration of roscovitine (a pan-Cdk inhibitor) attenuates renal cystic disease in juvenile cystic kidney (jck) mice. Cdk2 is a key regulator of cell proliferation, but its specific role in PKD r

Medieval Swedish Sermons on St. Olaf

Artikeln presenterar svensk senmedeltida helgonpredikan i allmänhet, några generella drag hos de ca 30 bevarade predikningarna om S:t Olof samt en mer ingående redogörelse för en av dessa.The contribution presents preserved medieval Nordic sermons on St Olaf, all of which are found in Latin manuscripts from the medieval library of Vadstena Abbey. After a brief discussion of what they sermons say about St Olaf and what sources the preachers may have used, the contents of one specific sermon are given in summary form.

Standardised measurement of physical capacity in young and middle-aged active adults with hip-related pain : Recommendations from the first International Hip-related Pain Research Network (IHiPRN) meeting, Zurich, 2018

Hip-related pain can significantly impact quality of life, function, work capacity, physical activity and family life. Standardised measurement methods of physical capacity of relevance to young and middle-aged active adults with hip-related pain are currently not established. The aim of this consensus paper was to provide recommendations for clinical practice and research on standardised measurem

Nomenclature and semantic descriptions of ulcerative and inflammatory lesions seen in Crohn’s disease in small bowel capsule endoscopy : An international Delphi consensus statement

Background: In the medical literature, the nomenclature and descriptions (ND) of small bowel (SB) ulcerative and inflammatory (U-I) lesions in capsule endoscopy (CE) are scarce and inconsistent. Inter-observer variability in interpreting these findings remains a major limitation in the assessment of the severity of mucosal lesions, which can impact negatively on clinical care, training and researc