Protein structure-function relationships can be studied by using linker insertion mutagenesis, which efficiently identifies essential regions in target proteins. Bacteriophage Mu in vitro DNA transposition was used to generate an extensive library of pentapeptide insertion mutants within the alpha-complementing domain 1 of Escherichia coli beta-galactosidase, yielding mutants at 100% efficiency. E

Den kinesiska utrikeshandelslagstiftningen genomgår en snabb omvandling. I två på varandra följande artiklar följs artikeln om utvecklingen av kinesisk handelsrätt i Svensk Juristtidning upp med en genomgång av Kinas immaterialrättsliga regelverk. I den första artikeln behandlas de nyligen antagna varumärkes- och patentlagarna med kortare utvikningar om anställda uppfinnare och upphovsrättsliga re

he health gains from risk reduction with regard to chemical health hazards have so far been most evident in the occupational setting. Development with regard to analytical and epidemiological methods, and possibilities to measure discrete effects, do however indicate health effects also at low levels of exposure, relevant for the general environment. Efficient risk reduction in the general, and ev

Simple analytical upper bounds, approximations and lower bounds on the error functionQ(x)are presented and analyzed. A class of functions are given, where the choice of two parameters result in good upper bounds, lower bounds and approximations onQ(x). The results are given in formulas, parameter tables and graphs. The approximations are suitable for programmable pocket calculators.

En intervju med sociologen Saskia Sassen om globaliseringen, liberalismen och demokratin.

The future of cellular radio ICs lies in the integration of an ever-increasing number of bands and channel bandwidths. This paper presents a transceiver together with the associated discrete front-end components. The transceiver supports 4 EDGE bands and 9 WCDMA bands (l-VI and Vlll-X), while the radio can be configured to simultaneously support the 4 EDGE bands and up to 5 WCDMA bands: 3 high ban

Aim: To present gender-specific normative data on estimates of neuromuscular performance, such as muscle strength, vertical jump and standing unilateral balance, in pre-pubertal children. Methods: Lean body mass (kg) and fat mass (%) were estimated by dual-energy X-ray absorptiometry in 246 boys and 190 girls aged 6-12 years in Tanner stages 1 and 2. Isokinetic concentric peak torque at 60 and 180

Using two-pulse photon echo excitation a strong resonance in the measured homogeneous dephasing time as a function of magnetic field is observed in the H-3(4)-D-1(2) transition of Pr3+:YAlO3. The resonance could only be observed at low excitation energies since it otherwise was masked by excitation intensity dependent extra dephasing processes in the crystal. Thus intensity dependent dephasing pro

The serine protease tissue-type plasminogen activator (t-PA) is involved in both vital physiological brain processes, such as synaptic plasticity, and pathophysiological conditions, such as neurodegeneration and ischemic stroke. Recent data suggest that epigenetic mechanisms play an important role in the regulation of t-PA in human endothelial cells. However, there are limited data on epigenetic r