Galectins are β-galactoside-binding lectins, which are present in both the intracellular and extracellular environments of cells. During the last two decades, galectins have gained increasing interest as drug targets in various diseases, such as chronic inflammation (fibrosis) and cancer, in which galectins have been shown to play important, and sometimes rate-limiting, roles. Galectins have e.g.

Admission to an emergency department can be considered a stressful event for both the child and the family. Due to the nature of traumas, illnesses and fatalities it is a chaotic forum in which good communication between child and staff can be difficult to establish. Purpose: The purpose of the study was to describe nurses' methods when interacting with children aged three to six at a pediatric em

This study examines the governance attributes of post-IPO (initial public offering) retained ownership of private equity in business group constituent firms in contrast to their unaffiliated counterparts, in 202 newly listed firms in 22 emerging African economies. We adopt an actor centered institutional-theoretic perspective in rationalizing institutional voids and the advantages of maintained go

Some complex plant-derived polysaccharides, such as modified citrus pectins and galactomannans, have been shown to have promising anti-inflammatory and anti-cancer effects. Most reports propose or claim that these effects are due to interaction of the polysaccharides with galectins because the polysaccharides contain galactose-containing side chains that might bind this class of lectin. However, t

The cancer microenvironment has been attracting increasing attention as the realization of its importance for both disease treatment and malignant progression. Here the aim was to elucidate some of the effects and mechanisms of the tumor microenvironment related to the extracellular matrix (ECM). We hypothesized that collagen fibril assembly is an instrumental component in the formation of the bar

The research area of Digitalization and Privacy, as defined and delimited within the context of this knowledge review, (mainly through the selection of search strings), is in a phase of development. The present study has been delimited to articles in English that have been published in scientific peer-reviewed journals. During the past ten years, the number of scientific articles per year has incr

I Norden finns ett antal gränsregioner, där arbetspendling, handel och andra kontakter över gränserna utgör naturliga inslag i vardagen. I alla de nordiska länderna finns hos regeringar och parlament en politisk strävan att gynna rörlighet mellan de nordiska länderna – men också ambitioner att skydda egna intressen och bevara inarbetade strukturer. Avsikten med artikeln är att i ljuset av denna spThe article explores the possibilities for legal research on Nordic border regions, highlighting border barriers, organizational structures for cooperation and public order and safety.

This paper investigates the multiple windows of the mean squared error optimal time-frequency kernel for estimation of the Wigner-Ville spectrum. The kernel is optimal for a certain locally stationary process where the covariance function is determined by two one-dimensional Gaussian functions. The multiple windows are obtained as the eigenvectors of the rotated time-lag estimation kernel. The spe

Carbon dioxide (CO 2) is the most important anthropogenic greenhouse gas contributing to about half of the total anthropogenic change in the Earth's radiation budget. And about half of the anthropogenic CO2 emissions stay in the atmosphere, the remainder is taken up by the biosphere. It is of paramount importance to better understand CO2 sources and sinks and their spatio-temporal distribution. In

Conditional knockout mice are commonly used to study the function of specific genes in hematopoiesis. Different promoters that drive Cre expression have been utilized, with the interferon-inducible Mx1-Cre still being the most commonly used “deleter strain” in experimental hematology. However, different pitfalls associated with this system could lead to misinterpretation in functional studies. We

Mervärdesskatt är en indirekt skatt som ger stora intäkter till staten. Företag lägger också mycket tid och resurser på att hantera den. Reglerna om mervärdesskatt består huvudsakligen av genomförande av de EU-rättsliga direktiv som finns inom området. Just det stora inflytandet av EU-rätten gör mervärdesskatten speciell och komplex.Mervärdesskatt i teori och tillämpning ger en introduktion i ämne

On 26 May 2016 the Court of Justice of the EU (CJEU) decided Bookit Ltd v HMRC (Bookit)1 which dealt with the interpretation of the exemption for transactions concerning payments within article 135(1)(d) of the Council Directive on the common system of value added tax (the VAT Directive).2 Article 135(1)(d) of the VAT Directive provides that Member States shall exempt "transactions, including nego

Partially premixed combustion (PPC) is used to meet the increasing demands of emission legislation and to improve fuel efficiency. With gasoline fuels, PPC has the advantage of a longer premixed duration of the fuel/air mixture, which prevents soot formation. In addition, the overall combustion stability can be increased with a longer ignition delay, providing proper fuel injection strategies. In