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Reduction of artifacts associated with missing data in coherent diffractive imaging
Coherent diffractive imaging experiments often collect incomplete datasets containing regions that lack any measurements. These regions can arise because of beamstops, gaps between detectors, or, in tomography experiments, a missing wedge of data due to a limited sample rotation range. We describe practical and effective approaches to mitigate reconstruction artifacts by bringing uniqueness back t
On the origin of an insular hybrid butterfly lineage
new species can form through hybridization between species. Hybrid speciation in animals has been intensely debated, partly because hard evidence for the process has been difficult to obtain. Here we report the discovery of a European hybrid butterfly lineage, a finding that can be considered surprising given the intense and long-term study of European butterflies. The lineage we describe is main
PopGLen-A Snakemake pipeline for performing population genomic analyses using genotype likelihood-based methods
SUMMARY: PopGLen is a Snakemake workflow for performing population genomic analyses within a genotype-likelihood framework, integrating steps for raw sequence processing of both historical and modern DNA, quality control, multiple filtering schemes, and population genomic analysis. Currently, the population genomic analyses included allow for estimating linkage disequilibrium, kinship, genetic div
Defining Excellence : The First Core Set of Quality Indicators for the European Paediatric Surgical Audit on Hirschsprung's Disease Care
Aim: This study aimed to develop a universally applicable core set of quality indicators for Hirschsprung's disease care through a consensus-driven process, to standardise and improve care quality across Europe. Methods: A modified Delphi method was used to achieve consensus among healthcare professionals (HPs) and patient representatives (PRs) across Europe. Participants completed three rounds of
Affordances and Limitations of Translanguaging and Writing Tools : A Study of Emergent Multilingual Students' Writing in EFL
Multilingual students writing in English as a foreign/second language has been a major topic in research for many years (see Leung & Valdés for overview). This topic is particularly relevant in Sweden, as reports suggest that students who are speakers of a language other than Swedish (LOTS) in the home have a lower grade average after 9 years of compulsory schooling (Skolinspektionen, 2010; Sk
ECOFOAM: 3D-printed flexible lattice structures
Balancing inflammation : the specific roles of serum amyloid A proteins in sterile and infectious diseases
Serum Amyloid A (SAA) proteins are acute-phase reactants with critical roles in sterile and bacterial inflammation. Through in vitro and in vivo experiments, we demonstrate that SAA proteins amplify cytokine and chemokine responses during sterile inflammation and enhance bacterial clearance in infectious conditions. Mechanistically, SAA proteins augment NF-κB signaling, driving pro and anti-infl
Regeneration of dimethyl carbonate and purification of 5-hydroxymethylfurfural used in a biphasic dehydration process through activated carbon adsorption and evaporation
The production of 5-hydroxymethylfurfural (HMF) is an important process for a future sustainable plastic industry. Hence many processes were developed to produce HMF, however, HMF recovery and solvent recyclability are limiting steps for the process development. Therefore, In this study, granulated activated carbon (GAC) was investigated as a purification step of HMF produced from fructose in a bi
Flexiblare finansregler med tveksam effekt
Många EU-länder kämpar med svaga offentliga finanser och i stora euroländer som Frankrike och Italien är den offentliga skulden över 100 procent av BNP. Trots strikta finanspolitiska regler har få länder lyckats hålla sina statsfinanser i schack – inte ens Tyskland. År 2024 reviderades reglerna i förhoppningen att det skall leda till mer robusta offentliga finanser i framtiden. Frågan är: löser de
Soluble cerebral Aβ protofibrils link Aβ plaque pathology to changes in CSF Aβ42/Aβ40 ratios, neurofilament light and tau in Alzheimer’s disease model mice
The Aβ42/Aβ40 ratio in the cerebrospinal fluid (CSF) and the concentrations of neurofilament light (NfL) and total tau (t-tau) are changed in the early stages of Alzheimer’s disease (AD)1, but their neurobiological correlates are not entirely understood. Here, we used 5xFAD transgenic mice to investigate the associations between these CSF biomarkers and measures of cerebral Aβ, including Aβ42/Aβ40
Heart rate response and recovery in cycle exercise testing : normal values and association with mortality
Aims. Chronotropic incompetence and impaired heart rate (HR) recovery are related to mortality. Guidelines lack specific reference values for HR recovery. We defined normal values and studied blunted HR response and recovery and mortality risk. Methods and results. We included 9917 subjects (45% females) aged 18–85 years who performed a cycle exercise test. We defined normal values for peak HR, HR
The place of Bulgarian and Russian in post-Talmian motion event typology : A Holistic Spatial Semantics Analysis
The traditional Talmian binary typology of satellite-framed vs. verb-framed languages has proven to be insufficient for showing the diversity across the world’s languages. One approach within post-Talmian motion typology follows Holistic Spatial Semantics, which has been applied to languages like Swedish, French, Thai and Telugu, but not to Slavic languages. This motivates the present research. We
Spatial QRS-T angle can indicate presence of myocardial fibrosis in pediatric and young adult patients with hypertrophic cardiomyopathy
Background: Myocardial fibrosis, expressed as late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR), is an important risk factor for malignant cardiac events in hypertrophic cardiomyopathy (HCM). However, CMR is not easily available, expensive, also needing intravenous access and contrast. Objective: To determine if derived vectorcardiographic spatial QRS-T angles, an aspec
Prognostic relevance of CD163+ immune cells in patients with metastatic breast cancer
Metastatic breast cancer (MBC) is generally considered an incurable disease and even though new treatments are available, the median survival is approximately three years. The introduction of immune therapies for MBC highlights the importance of the immune system in cancer progression and treatment. CD163+ anti-inflammatory myeloid cells, including tumor associated macrophages (TAMs), are known to
The struggle of leadership work: Three interactional challenges in mobilizing actors to commit to future action
Although it is widely recognized that leadership concerns organizing future actions and mobilizing organizational actors to pursue them, our understanding of how this is accomplished in situated work interactions is relatively limited. Recent ethnographic studies have focused on leadership work resulting in the emergence of direction. This study explores the efforts involved in attempting to mobilAlthough it is widely recognized that leadership concerns organizing future actions and mobilizing organizational actors to pursue them, our understanding of how this is accomplished in situated work interactions is relatively limited. Recent ethnographic studies have focused on leadership work resulting in the emergence of direction. This study explores the efforts involved in attempting to mobil
Knivkontakt: mot en kirurgisk karriär
"Knivkontakt" av Hagelsteen & Frost - din guide till en framgångsrik ST i kirurgiska specialiteter. Lär dig navigera i kirurgvärlden, ta ansvar för ditt lärande, hantera utmaningar och utveckla rätt mindset. Praktiska tips från erfarna kirurger i fickformat!Finns nu hos alla nätbokhandlare. Kliniker som önskar köpa större volymer till rabatterat pris kan kontakta författarna.
Modelling the Evolution of Species’ Ranges
Att arter har begränsade geografiska utbredningsområden beror ofta på en begränsad förmåga att anpassa sig till de miljöförhållanden som råder utanför arternas utbredningsgränser. På grund av pågående klimatförändringar kan dock de miljöförhållanden som råder inom arters nuvarande utbredningsområden komma att ändras inom den närmaste framtiden. För att undgå utrotning kommer därför många populatioThe fact that species have limited ranges is often due to a limited ability to adapt to the environmental conditions that occur outside their geographic ranges. However, due to ongoing climate change, the environmental conditions within species’ geographic ranges may change in the near-future. To avoid extinction, many populations therefore need to migrate to new areas and/or adapt to the new cond
Acute unilateral vestibulopathy and corticosteroid treatment - A randomized placebo-controlled double-blind trial
BACKGROUND: The efficacy of corticosteroids for treating acute vestibular neuritis, or acute unilateral vestibulopathy (AUVP), remains controversial.OBJECTIVE: This study aimed to evaluate whether corticosteroids improve vestibular function and reduce symptoms in both acute and chronic phases of AUVP.METHODS: This randomized, placebo-controlled, double-blind trial included patients with AUVP (ages
Unconventional gap structures and the intermediate mixed state: A vortex lattice study of the noncentrosymmetric superconductor BiPd
We report on neutron scattering measurements on the vortex lattice of the noncentrosymmetric superconductor BiPd. We observe the existence of the intermediate mixed state, a region where Meissner and vortex lattice phases coexist, which is a feature of low type-II superconductors. Following this, we obtain an estimate of the value of using the extended London model. Finally, we find that the tempe