Elevated plasma levels of oxidized low-density lipoprotein (oxLDL) are a risk factor and key component that accelerates and worsens cardiovascular disease fueling inflammation, plaque buildup and vascular damage. OxLDL can elicit its detrimental action via lectin-like oxLDL receptor 1 (LOX-1). In this study, we determined whether oxLDL, via LOX-1, alters aortic vascular reactivity and determined i

Nonoverlapping domain decomposition methods have been utilized for a long time to solve linear and nonlinear elliptic problems, and more recently, parabolic problems. Despite this, there is no convergence theory for nonlinear elliptic and parabolic equations on general Lipschitz domains in Rd, d ≥ 2. We therefore develop a Steklov–Poincaré theory for nonlinear elliptic and parabolic problems and s

Background: Although glomerular diseases are the third most frequent cause of end-stage kidney disease worldwide, little is known about their long-term outcomes. Methods: In patients with chronic kidney disease (CKD) stage 3–5 enrolled in the Swedish Renal Registry, we compared risks of hospitalization, kidney replacement therapy (KRT), major cardiovascular events (MACE), and death of the four mos

The Baltic Sea has a generally low biodiversity, and several species are declining due to high anthropogenic pressure. One example is the Baltic Sea cod (Gadus morhua, L.), the cod has decreased since the 1980s in both biomass and abundance. One potential solution to increase the cod population is to improve settling ground and provide shelter for juveniles in artificial reefs. The Hanö Cod Reef p

Stimuli-responsive polymers stand out for their ability to respond to small environmental changes. One of the most representative thermo-sensitive materials is poly(N-isopropyl acrylamide) (PNIPAm), which presents reversible phase transitions close to the human body temperature. However, previous studies observed that the copolymerization of NIPAm with small quantities of different monomers like a

The mitochondrial protein NAD(P) + transhydrogenase (NNT) has been implicated in the metabolic derangements observed in obesity. Mice with the C57BL/6J genetic background bear a spontaneous mutation in the Nnt gene and are known to exhibit increased susceptibility to diet-induced metabolic disorders. Most of the studies on NNT in the context of diet-induced obesity have compared C57BL/6J mice with

We present a novel approach to the 3D sound source localization task for distributed ad-hoc microphone arrays by formulating it as a set-to-set regression problem. By training a multi-modal masked autoencoder model that operates on audio recordings and microphone coordinates, we show that such a formulation allows for accurate localization of the sound source, by reconstructing coordinates masked

How does emigration affect sending states’ welfare policies? Existing migration literature has identified numerous political, economic, and institutional variables that influence sending states’ approaches towards emigrants’ welfare. However, this literature has neglected broader processes of social transformation in sending states. Using the concept of welfare regime transnationalization, we show

Den europeiska textilindustrin står inför stora förändringar när EU:s nya förordning "Ecodesign for Sustainable Products Regulation" (ESPR) träder i kraft. En central del av regleringen är förbudet mot förstörelse av osålda konsumentprodukter, en åtgärd som syftar till att minska miljöpåverkan och öka hållbarheten inom modeindustrin. Studiens mål är att undersöka hur textilindustrin förbStatistics show that approximately 2,71 billion people have at some point shopped for clothes online (Sellers Commerce, 2022). E-commerce is becoming more and more common rather than to buy and try on clothes in a physical store which has led to many clothes being returned for various reasons (poor fit, free returns, etc.). The fast fashion industry generates significant textile waste, with unsold

Aims: Type 2 diabetes (T2D) patients with a clinical phenotype characterized by a high degree of insulin resistance are at increased risk of chronic kidney disease (CKD). We previously demonstrated that the endothelin receptor antagonist (ERA) atrasentan reduced insulin resistance in T2D. In this study, we compared the effect of atrasentan on insulin resistance across different phenotypic clusters

The emerging debate on transnational populism has thus far mainly focused on cases, which have remained relatively inconsequential due to the weak institutionalisation of the political transnationalism arena. By bringing in a better-structured arena of migrant transnationalism, this paper introduces populist political parties mobilising transnational migrants to the debate and explores the resulti

In the work of writing this report, four leading municipal research environments - CERUM, CKS, KEFU, and KFi - with the support of Kommuninvest, have collaborated to explore and understand the complex challenges that Swedish municipalities have had to manage during the transition from relatively favorable economic times to more challenging times, including changed economic conditions and a deterio

Background: The transcription factor Signal Transducer and Activator of Transcription 3 (STAT3) plays a role in carcinogenesis and is involved in processes, such as proliferation, differentiation, drug resistance and immunosuppression. STAT3 can be activated by phosphorylation of tyrosine at position 705 (pSTAT3Tyr705) or serine at 727 (pSTAT3Ser727). High expression levels of pSTAT3 are implicate

Hur kan svenska kommuner navigera i en alltmer komplex och osäker framtid? Med intervjuer och dokumentstudier från elva kommuner blottlägger en ny studie de strategiska utmaningarna och belyser vikten av balans mellan kapacitet och öppenhet för nya lösningar. Fyra kommuntyper träder fram.

The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no multidisciplinary consensus document has examined the perioperative considerations of how to best manage these patients. To address this challenge, this perioperative utilization of ECLS in l

Background: Postinfectious autoimmune processes have been proposed as potential causal risk factors for obsessive-compulsive disorder (OCD). In this large population-based study, we aimed to clarify the familial coaggregation pattern between severe infections and OCD across clusters of relatives with varying degrees of relatedness. Methods: We identified 4,916,898 individuals born in Sweden betwee