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Disentangling seasonal bacterioplankton population dynamics by high-frequency sampling

Multiyear comparisons of bacterioplankton succession reveal that environmental conditions drive community shifts with repeatable patterns between years. However, corresponding insight into bacterioplankton dynamics at a temporal resolution relevant for detailed examination of variation and characteristics of specific populations within years is essentially lacking. During 1 year, we collected 46 s

Evaluation of terrestrial pan-Arctic carbon cycling using a data-assimilation system

There is a significant knowledge gap in the current state of the terrestrial carbon (C) budget. Recent studies have highlighted a poor understanding particularly of C pool transit times and of whether productivity or biomass dominate these biases. The Arctic, accounting for approximately 50% of the global soil organic C stocks, has an important role in the global C cycle. Here, we use the CARbon D

Ultrafast THz Probe of Photoinduced Polarons in Lead-Halide Perovskites

We study the nature of photoexcited charge carriers in CsPbBr3 nanocrystal thin films by ultrafast optical pump-THz probe spectroscopy. We observe a deviation from a pure Drude dispersion of the THz dielectric response that is ascribed to the polaronic nature of carriers; a transient blueshift of observed phonon frequencies is indicative of the coupling between photogenerated charges and stretchin

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Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [ 18 F]ENL30 : A Potential PET Radiotracer for the 5-HT 7 Receptor

The 5-HT 7 receptor (5-HT 7 R) is involved in a broad range of physiological conditions and disorders. Currently, there is no validated clinical positron emission tomography (PET) tracer available; however, we have recently developed a promising 11 C-labeled candidate. In this project, we aimed to further extend our efforts and develop an 18 F-labeled derivative, coined [ 18 F]ENL30. Fluorin

Lactobacillus fermentum and Lactobacillus plantarum increased gut microbiota diversity and functionality, and mitigated Enterobacteriaceae, in a mouse model

Probiotics should bring ‘balance’ to the intestinal microbiota by stimulating beneficial bacteria, whilst mitigating adverse ones. Balance can also be interpreted as high alpha-diversity. Contrary, Escherichia coli is often regarded as an adverse component of the resident intestinal microbiota. The aim of the present study was to implement a mouse model for in vivo screening of Lactobacillus-strai

A Sustainable Crowdsourced Delivery System to Foster Free-Floating Bike-Sharing

Since bicycles and bike-sharing systems are becoming increasingly important in modern transportation contexts, we suggest in this paper an alternative method to incorporate cycling among the freight transport alternatives within urban areas. We propose pursuing a sustainable initiative of crowdsourced delivery where some of the urban good deliveries may be voluntarily undertaken by users of the fr

Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis

Streptococcus pyogenes (Group A streptococcus; GAS) is a human pathogen causing diseases from uncomplicated tonsillitis to life-threatening invasive infections. GAS secretes EndoS, an endoglycosidase that specifically cleaves the conserved N-glycan on IgG antibodies. In vitro, removal of this glycan impairs IgG effector functions, but its relevance to GAS infection in vivo is unclear. Using target

Surrogate safety measures and traffic conflict observations.

The chapter primarily focuses on observing traffic conflicts (also known as near-accidents) as a site-based road safety analysis technique. Traffic conflicts are a type of surrogate safety measure. The term surrogate indicates that non-accident-based indicators are used to assess VRU safety instead ofthe more traditional approach focusing on accidents (see chapter 2). The theory underpinning surro

Mechanistic Toxicology : Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization

Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. Traditionally, such risk assessments have been based on animal tests, but due to sever

Agreement between test procedures for the single-leg hop for distance and the single-leg mini squat as measures of lower extremity function

Background: Different test procedures are often used within performance-based measures, causing uncertainty as to whether results can be compared between studies. Thus, the aim of this study was to assess agreement between different test procedures for the single-leg hop for distance (SLHD) and the single-leg mini squat (SLMS), respectively, two commonly used tasks for assessing deficiency in lowe