In recent years we have observed how electromagnetic (EM) radiation enters our daily life. The strength of man-made EM field is often far above the natural level and this finding has encouraged a large group of researchers to investigate its possible health effect. Non-ionizing radiation and extremely low-frequency electric and magnetic fields have been the subject of intensive theoretical and exp

Development of inhibitory antibodies to infused factor VIII (FVIII) concentrates continues to be the most serious complication of haemophilia A management. Induction of immune tolerance by administering high doses of FVIII concentrate (antigen) and prothrombin complex concentrates to control bleeding was originated in the 1970s in Bonn, Germany, by Dr Hans-Hermann Brackmann, and became known as th

Purpose: To assess the diagnostic test accuracy and sources of heterogeneity for the discriminative potential of diffusion kurtosis imaging (DKI) to differentiate low-grade glioma (LGG) (World Health Organization [WHO] grade II) from high-grade glioma (HGG) (WHO grade III or IV). Materials and Methods: The Cochrane Library, Embase, Medline, and the Web of Science Core Collection were systematicall

Purpose Asthma is frequently reported in endurance athletes. The aim of the present study was to assess the long-term airway inflammatory response to endurance exercise in high-level athletes with and without asthma. Methods In a cross-sectional design, 20 asthmatic athletes (10 swimmers and 10 cross-country skiers), 19 athletes without asthma (10 swimmers and 9 cross-country skiers), and 24 healt

We present some work in progress based on observations of the use of version Control systems in two different software development organizations. We consider the emergent user experience, and analyze the structure of the conceptual model and its presentation to see how this experience is formed. We consider its impact on the adoption of such tools outside software engineering and suggest future li

Background: The developmental study of subtypes of disordered eating (DE) during adolescence may be relevant to understand the development of eating disorders. The purpose of the present study was to identify subgroups with different profiles of DE in a community sample of adolescent girls aged 13-15 years, and to study the stability of these profiles and subgroups over a one-year interval in orde

Static analysis tools help developers find bugs, improve code readability, and ensure consistent style across a project. However, these tools can be difficult to smoothly integrate with each other and into the developer workflow, particularly when scaling to large codebases. We present Tricorder, a program analysis platform aimed at building a data-driven ecosystem around program analysis. We pres

In applications spanning from image analysis and speech recognition to energy dissipation in turbulence and time-to failure of fatigued materials, researchers and engineers want to calculate how often a stochastic observable crosses a specific level, such as zero. At first glance this problem looks simple, but it is in fact theoretically very challenging, and therefore few exact results exist. One

Background: The patient’s view of their mental health is a central aspect in research and practice. Yet, little is known about which psychopathological symptoms are linked with patients’ satisfaction with their mental health. We aimed to identify these symptoms in patients with schizophrenia. Methods: An individual patient data meta-analysis was conducted with data from 2,488 patients from 8 indep

Ozone vapor, O3, is here visualized in a gliding arc discharge using photofragmentation laser-induced fluorescence. Ozone is imaged by first photodissociating the O3 molecule into an O radical and a vibrationally hot O2 fragment by a pump photon. Thereafter, the vibrationally excited O2 molecule absorbs a second (probe) photon that further transits the O2-molecule to an excited electronic state, a

Background: We studied the efficacy and safety of mycophenolate mofetil (MMF) and tacrolimus as second-line therapy in pediatric patients with autoimmune hepatitis (AIH) who were intolerant or non-responders to standard therapy (corticosteroid and azathioprine). Patients and Methods: We performed a retrospective study of data from 13 centers in Europe, USA, and Canada. Thirty-eight patients (< 18

In this contribution we present a constitutive modelling framework for magnetic shape memory alloys (MSMA) that builds on a global variational principle. The approach relies on concepts of energy relaxation and generalised notions of convexity to compute effective energy hulls to the non-convex energy landscape associated with the underlying multi-phase solid, from which the prediction of microstr

Starch nanoparticles (SNPs) are a promising choice for the strategic development of new renewable and biodegradable nanomaterials for novel biomedical and pharmaceutical applications when loaded with antibiotics or with anticancer agents as target drug delivery systems. The final properties of the SNPs are strongly influenced by the synthesis method and conditions being a controlled and monodisper

The Wnt signalling pathway is a central communication cascade between cells to orchestrate polarity and fate during development and adult tissue homeostasis in various organisms. This pathway can be regulated by different signalling molecules in several steps. One of the coordinators in this pathway is Nemo-like kinase (NLK), which is an atypical proline-directed serine/threonine mitogen-activated

A search for Higgs boson decays into a Z boson and a light resonance in two-lepton plus jet events is performed, using a pp collision dataset with an integrated luminosity of 139 fb-1 collected at s=13 TeV by the ATLAS experiment at the CERN LHC. The resonance considered is a light boson with a mass below 4 GeV from a possible extended scalar sector or a charmonium state. Multivariate discriminant

Most stars form in a clustered environment. Both single and binary stars will sometimes encounter planetary systems in such crowded environments. Encounter rates for binaries may be larger than for single stars, even for binary fractions as low as 10-20 per cent. In this work, we investigate scatterings between a Sun-Jupiter pair and both binary and single stars as in young clusters.We first perfo

Enterohemorrhagic and enteropathogenic Escherichia coli are among the most important food-borne pathogens, posing a global health threat. The virulence factor intimin is essential for the attachment of pathogenic E. coli to the intestinal host cell. Intimin consists of four extracellular bacterial immunoglobulin-like (Big) domains, D00–D2, extending into the fifth lectin subdomain (D3) that binds