Research is needed to understand attitudes toward and adoption of the broad range of technologies available to support active and healthy aging in different generations. The present article gives an overview of the GenerationTech survey and sample, and describes attitudes and acceptance related to technology in general and as a means to support active and healthy aging. A national survey was condu

Genetic variation at the MTIF3 (Mitochondrial Translational Initiation Factor 3) locus has been robustly associated with obesity in humans, but the functional basis behind this association is not known. Here, we applied luciferase reporter assay to map potential functional variants in the haplotype block tagged by rs1885988 and used CRISPR-Cas9 to edit the potential functional variants to confirm

Interpreting the social complexity of the Roman house requires a careful evaluation of existing evidence. With this in mind, recent work in the field has proposed a variety of different approaches, focusing each time on a specific type of source (architecture and décor, ancient texts, material evidence from excavated houses), each in turn recursively deemed more adequate for the purpose or more fr

In this paper, we present an adaptive spectral projection based finite element method to numerically approximate the solution of the wave equation with memory. The adaptivity is not restricted to the mesh (hp-adaptivity), but it is also applied to the size of the computed spectrum (k-adaptivity). The meshes are refined using a residual based error estimator, while the size of the computed spectrum

An improved model for pure rotational coherent anti-Stokes Raman scattering (CARS) has been developed or the dual-broadband approach. This model takes into account the fact that coherent anti-Stokes as well as Stokes radiation are generated simultaneously, and these two branches overlap and interact at high pressures giving rise to an inter-branch interference effect. In combustion studies, the an

Previously unknown aspects in the life cycle of the freshwater flagellate Gonyostomum semen (Ehrenb.) (Raphidophyceae) are described here. This species forms intense blooms in many northern temperate lakes, and has increased in abundance and frequency in northern Europe during the past decades. The proposed life cycle is based on observations of life cycle stages and transitions in cultures. Viabl

The filamentous fungus Penicillium brasilianum IBT 20888 was cultivated on a mixture of 30 g l−1 cellulose and 10 g l−1 xylan for 111 h and the resulting culture filtrate was used for protein purification. From the cultivation broth, five cellulases and one xylanase were purified. Hydrolysis studies revealed that two of the cellulases were acting as cellobiohydrolases by being active on only micro

Trends in energy intensities for 31 countries are evaluated, over the period from 1950 to 1988, using a purchasing power parity-based GDP measure and United Nations energy statistics. With non-commercial energy included, the energy intensities of low income countries are similar to those of high income countries. Energy intensities have decreased for 15 out of the 31 countries studied. The analysi

This article describes a study where laboratory and theoretical work on the fundamental hygro-mechanical behaviour of wood is applied on convective drying of sawn timber. A material model describing the behaviour of wood during drying is used to simulate drying stresses in timber. Cross-sections containing heartwood, sapwood and a combination of both are studied. Simulations are compared with meas

Relapsing polychondritis ( RP) is an autoimmune disease that affects extra-articular cartilage. Matrilin-1-induced relapsing polychondritis (MIRP) is a model for RP and is useful for studies of the pathogenic mechanisms in this disease. There are indications that the major histocompatibility complex (MHC) class II plays a major role in RP, since DR4(+) patients are more commonly affected than cont

A detailed experimental investigation has been made of the pyrolysis-the first step in biomass combustion-of single birchwood particles. In addition to mass spectrometric and gravimetric analysis, the pyrolysis volatiles were characterized by different optical techniques. Absorption measurements showed a nearly featureless absorption in the ultraviolet spectral region with a continuously stronger