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Climate-Change-Driven Shifts in Aegilops tauschii Species Distribution : Implications for Food Security and Ecological Conservation
Climate change has diverse effects on the planet’s environment, including changes and shifts in the distribution and abundance of species. In this paper, we present a robust prediction ensemble algorithm for the current and future species distribution of Aegilops tauschii. Four modeling approaches were trained using various environmental variables (bioclimatic and soil variables) to accurately pre
Sweden is a nearly cashless society – here’s how it affects people who are left out
Niklas Antonsson : För samhällets bestånd och Guds rikes förkovran. Prästerskapets undervisning kring hushåll, barn och äktenskap i svenska postillor 1686–1770
‘A woman is not a baby-making machine’ : a brief history of South Korea’s 4B movement – and why it’s making waves in America
Combination and summary of ATLAS dark matter searches interpreted in a 2HDM with a pseudo-scalar mediator using 139 fb−1 of s=13 TeV pp collision data
Results from a wide range of searches targeting different experimental signatures with and without missing transverse momentum (ETmiss) are used to constrain a Two-Higgs-Doublet Model (2HDM) with an additional pseudo-scalar mediating the interaction between ordinary and dark matter (2HDM+a). The analyses use up to 139 fb−1 of proton–proton collision data at a centre-of-mass energy s=13 TeV recorde
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Bridging silos through governance innovations: the role of the EU cities mission
Cities and local governments are increasingly under pressure to accelerate transformative change in energy and climate transitions. To help cities in their climate actions, the European Commission (EC) has established the EU Cities Mission, which aims for climate neutrality by 2030 for participating cities. The literature argues that one of the main obstacles to accelerating decarbonization lies i
HLA investigation in ICI-induced T1D and isolated ACTH deficiency including meta-analysis
OBJECTIVE: Widespread use of immune checkpoint inhibitors (ICIs) in cancer treatment has led to an increase in the number of reported cases of immunotherapy-related endocrinopathies. This study aimed to analyze and compare human leukocyte antigen (HLA) signatures associated with ICI-induced type 1 diabetes (ICI-T1D) and isolated adrenocorticotropic hormone deficiency (ICI-IAD) in patients with bot
Beneficial effect of oral semaglutide for type 2 diabetes mellitus in patients with metabolic dysfunction-associated steatotic liver disease : A prospective, multicentre, observational study
AIMS: To evaluate the efficacy and safety of oral semaglutide for type 2 diabetes mellitus (T2DM) in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).MATERIALS AND METHODS: This was a single-arm, multicentre, prospective study. Among 80 consecutive patients with MASLD and T2DM who newly received oral semaglutide, 70 completed 48-week oral semaglutide treatment as sche
Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis
Type 2 diabetes is associated with cardiovascular disease, possibly due to impaired vascular fibrous repair. Yet, the mechanisms are elusive. Here, we investigate alterations in the fibrous repair processes in type 2 diabetes atherosclerotic plaque extracellular matrix by combining multi-omics from the human Carotid Plaque Imaging Project cohort and functional studies. Plaques from type 2 diabetes
Glucose regulation and association with Vitamin D and parathyroid hormone – differences across Middle Eastern and Caucasian ethnicities
Background: Middle Eastern (ME) immigrants to Europe have a heavy burden of metabolic disorders including a higher prevalence of insulin resistance, T2D and obesity as compared to native-born Europeans. Vitamin D insufficiency and deficiency are prevalent conditions in people originating from the ME. Aims: To study the differences in the levels of 25(OH)D and parathyroid hormone (PTH) across ME an
Engaging with young professionals in transfusion medicine : Insights from a needs assessment survey targeting an international cohort
BACKGROUND AND OBJECTIVES: Professionals who work or study in transfusion medicine under 40 years of age are considered young professionals (YPs) by the International Society of Blood Transfusion (ISBT). While the ISBT provides opportunities for YPs, their needs have to be assessed to customize initiatives in a way that could potentially improve their engagement. This survey aimed to assess the ne
Educational and professional development in Swedish higher education
We invite all interested participants into an exploratory workshop about possible research designs for studying the relationship between educational and professional development in Swedish higher education. The authors’ experience from working in Swedish higher education for a long time is that there are some stories about this relationship that are more frequent than others. The aim of our planne
Definite article use with generic reference in German : an empirical study
This study is concerned with the distribution of the definite article inGerman with plural nominals that have a generic reading. In Standard German,genericity is typically expressed by bare nouns (Tiger sind gefährlich‘Tigers aredangerous’). Many researchers have claimed that there is variation in articleuse in the expression of generic reference in German (e.g., Brugger 1993; Longobardi 1994; Kri
Targeting MarA N-terminal domain dynamics to prevent DNA binding
Efflux is one of the mechanisms employed by Gram-negative bacteria to become resistant to routinely used antibiotics. The inhibition of efflux by targeting their regulators is a promising strategy to re-sensitize bacterial pathogens to antibiotics. AcrAB-TolC is the main resistance-nodulation-division efflux pump in Enterobacteriaceae. MarA is an AraC/XylS family global regulator that regulates mo
Risk of colorectal cancer associated with frequency of colorectal polyp diagnosis in relatives
BACKGROUND & AIMS: We aimed to evaluate the association of frequency of polyp diagnosis in relatives with the risk of overall and early-onset colorectal cancer (CRC).METHODS: We leveraged data from nationwide Swedish family cancer datasets (1964-2018) to calculate standardized incidence ratios (SIRs) for individuals with a family history of polyp by frequency of polyp diagnosis in family membe
Nondeterminacy, two-step models and justified choice
This article analyzes approaches to nondeterminacy (e.g., incommensurability, indeterminacy, parity) that suggest that one can make justified choices when primary criteria fail to fully determine a best alternative by introducing a secondary criterion. It is shown that these approaches (in the article called “two-step models”) risk violating Basic Contraction Consistency. Some ways of adjusting tw
"Samhället accepterar inte våld i nära relation” En kvalitativ studie om implementeringen av projektet Trygg relation – fri från våld i Malmö stad
Intimate partner violence is a widespread problem both globally and in Sweden. A method called Intimate partner violence intervention (IPVI) was developed in the United States and has been introduced in Sweden, where it is currently being implemented in Malmö. Therefore, this study aimed to explore the implementation of the project Trygg relation - fri från våld in Malmö stad. The chosen method fo
From support to obligation: A content analysis of the welfare recipient's role in Swedish activation policy
This research aims to analyze the development of activation policies in Sweden from the 1990s to the present, with a particular focus on how legislative proposals and public inquiries (SOU) have redefined the perception of welfare recipients. The study investigates how recipients have been described in policy documents and how their rights and obligations have evolved. By examining these changes,