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Using three independent archival sources, we previously documented substantial declines in stunting and wasting in Portugal during the mid-twentieth century. This note revisits the original evidence, clarifies the descriptive scope of our analysis, and situates the observed anthropo-metric changes within the broader evolution of public health, nutrition, and social policy in Portugal. We show that
1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030, 1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030,
Aims ECG monitoring is often required during critical phases of illness. To evaluate the role of modern technology and advanced analytical algorithms artificial intelligence compared with standard-of care, we undertook a prospective, head-to-head comparison of a novel, cable-free, patch-based, and AI-enhanced electrocardiography system (CardioSenseSystem) with standard of care (SOC) ECG monitoring
A real-time optical imaging system has been developed and commissioned at the European Spallation Source (ESS) to monitor the high-power proton beam at the tuning beam dump, and provide machine protection. The system employs chromium-doped alumina (Chromox) luminescent screens imaged by radiation-shielded optics and a CMOS camera. Real-time FPGA-based processing extracts beam size and position, de
Background Hypochondriasis, or health anxiety disorder, is associated with increased mortality, mainly from potentially preventable causes. Substance misuse is a well-known contributor to premature death, yet its relationship with hypochondriasis remains unclear. We assessed the risk of broadly defined substance-related problems in individuals diagnosed with hypochondriasis. Methods This Swedish r
This paper examines firefighter exposure to emissions during actual firefighting in building scenarios. The focus is on actual exposure, not small-scale lab tests, to identify research gaps in light of the International Agency for Research on Cancer (IARC) classification of firefighting as an occupation with a heightened risk for certain types of cancer. The work is based on a systematic literatur
Characterizing the effect of pesticides on pollinators is essential in the strive to protect biodiversity while maintaining efficient food production. Metabolomics offers detailed insight into the physiological response to pesticides. The impact of pre-dissection and dissection methodology on the metabolic response remains largely unknown, as does their possible effect on the measured metabolic re
SARS-CoV-2 breakthrough infections (BTIs) are relatively common, but little is known in terms of differentiating responses associated with asymptomatic BTI (ABTI) versus symptomatic BTI (SBTI). Here, we investigated the impact of ABTI and SBTI on antibody and T-cell responses toward Spike. SBTI donors had significantly higher plasma anti-Spike RBD IgG titers compared to both ABTI and SARS-CoV-2 va
Background Parenthood is consistently identified as a protective factor for suicidal behavior. However, it remains unclear whether this relationship varies as a function of sex, age, time since birth, number of children, and other risk/protective factors. Methods We used Cox proportional hazards models to describe the relationship between the birth of up to four children and suicide attempt (SA) r
A major challenge hampering the industrial and biological exploitation of lipases is the self-limiting effect of the lipolytic reaction. Defying sustained attention throughout history, the influence of lipase catalysed lipolysis on the internal structure of thin triglyceride films has proved elusive. An in-depth understanding of the lipolysis process at the triglycerides/aqueous interface will ass
Rhesus macaques (RMs) are a vital model for studying human disease and are invaluable to preclinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust genetic resources for antibody-encoding genes within the immunoglobulin (IG) loci. The complexity of the IG loci has historically made them challenging to characterize accurately. To
Drawing on the theoretical framework of ‘relational work’ in economic sociology, the article examines the phenomenon of ‘precarious commitment’ – when employees’ commitment to their work and colleagues simultaneously exposes them to the risk of self-exploitation. The study analyses semi-structured interviews with game developers in the Swedish digital games industry. The article demonstrates the n
Background: Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) frequently co-occur in youth. Integrated, trauma-focused treatments are recommended, but evidence in youth is limited and the dynamics of symptom change are poorly understood.Objectives: We investigated within-treatment changes in PTSD and substance use, and their temporal sequencing, in a randomised controlled tria
Antibiotic resistance poses a significant threat to human health, and wastewater treatment plants (WWTPs) are important reservoirs of antibiotic resistance genes (ARGs). Here, we analyze the antibiotic resistomes of 226 activated sludge samples from 142 WWTPs across six continents, using a consistent pipeline for sample collection, DNA sequencing and analysis. We find that ARGs are diverse and sim
The first measurement of the polarisation of coherently photoproduced J/ψ mesons in ultra-peripheral Pb–Pb collisions, using data at sNN=5.02 TeV, is presented. The J/ψ meson is measured via its dimuon decay channel in the forward rapidity interval −4.0
Background: Asthma characterization using blood eosinophil count (BEC) (among other biomarkers and clinical indices) is recommended in severe asthma (SA), but the masking effect of oral corticosteroids (OCS), makes this challenging. Aim: Our aim was to explore the effect of OCS use (both intermittent [iOCS] and long-term [LTOCS]) prior to biologic initiation on SA phenotype and biomarker profile i
Six coumarins were isolated from two bioactive fractions of the 70% ethanol extract from the twigs and leaves of Wikstroemia indica (L.) C.A. Mey. (Thymelaeaceae), namely the ethyl acetate fraction (WIE) and the water fraction (WIW). These compounds were identified as umbelliferone (1), daphnoretin (2), daphnorin (3), adicardin (4), wikstronutin (5), and triumbelletin-7-O-β-D-glucoside (6). Compou
Complement factor C3 is one of the most abundant proteins in the bloodstream and a central part of the complement system. Upon activation, C3 facilitates bacterial recognition and clearance in the extracellular environment. Initially regarded as a serum effector component, C3 is also emerging as an intracellular protein regulating basic cellular processes. Previously, we reported that intracellula
